ID   PEX22_KLULA             Reviewed;         156 AA.
AC   Q6CLU6;
DT   25-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=Peroxisome assembly protein 22;
DE   AltName: Full=Peroxin-22;
GN   Name=PEX22; OrderedLocusNames=KLLA0F00308g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in peroxisome biogenesis. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Peroxisome membrane {ECO:0000250}; Single-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the peroxin-22 family. {ECO:0000305}.
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DR   EMBL; CR382126; CAG97800.1; -; Genomic_DNA.
DR   RefSeq; XP_455093.1; XM_455093.1.
DR   AlphaFoldDB; Q6CLU6; -.
DR   SMR; Q6CLU6; -.
DR   STRING; 28985.XP_455093.1; -.
DR   EnsemblFungi; CAG97800; CAG97800; KLLA0_F00308g.
DR   GeneID; 2895132; -.
DR   KEGG; kla:KLLA0_F00308g; -.
DR   eggNOG; ENOG502SFA5; Eukaryota.
DR   HOGENOM; CLU_1686888_0_0_1; -.
DR   InParanoid; Q6CLU6; -.
DR   OMA; LEDSIWP; -.
DR   Proteomes; UP000000598; Chromosome F.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0007031; P:peroxisome organization; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.11730; -; 1.
DR   InterPro; IPR024359; Peroxin-22.
DR   InterPro; IPR038613; Peroxin-22_C_sf.
DR   Pfam; PF12827; Peroxin-22; 1.
PE   3: Inferred from homology;
KW   Membrane; Peroxisome; Peroxisome biogenesis; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..156
FT                   /note="Peroxisome assembly protein 22"
FT                   /id="PRO_0000058337"
FT   TRANSMEM        24..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   156 AA;  17977 MW;  C667761972A8F30D CRC64;
     MRGDKETTNW LNKSLMKQAR QKKLSIIAVG VLSTVAVTVG YLLYLYRGQR NPNIRDVKPK
     SKCYVLTQDL FDKIENWQEE LSKDSVMLVL PEVAHLGNHL KLQLSSIEHK IVIFNNSSAV
     WSAVRHLKKY ELVISRDKTS DMPVDLRRYV GQISHI