PEX32_SCHPO
ID PEX32_SCHPO Reviewed; 535 AA.
AC O59807;
DT 16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1998, sequence version 1.
DT 03-AUG-2022, entry version 97.
DE RecName: Full=Peroxisomal membrane protein pex32;
DE AltName: Full=Peroxin-32;
GN Name=pex32; ORFNames=SPCC550.09;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
CC -!- SUBCELLULAR LOCATION: Peroxisome membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the PEX28-32 family. PEX32 subfamily.
CC {ECO:0000305}.
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DR EMBL; CU329672; CAA19113.1; -; Genomic_DNA.
DR PIR; T41384; T41384.
DR RefSeq; NP_588101.1; NM_001023092.2.
DR AlphaFoldDB; O59807; -.
DR SMR; O59807; -.
DR BioGRID; 276020; 3.
DR STRING; 4896.SPCC550.09.1; -.
DR iPTMnet; O59807; -.
DR MaxQB; O59807; -.
DR PaxDb; O59807; -.
DR PRIDE; O59807; -.
DR EnsemblFungi; SPCC550.09.1; SPCC550.09.1:pep; SPCC550.09.
DR GeneID; 2539457; -.
DR KEGG; spo:SPCC550.09; -.
DR PomBase; SPCC550.09; pex32.
DR VEuPathDB; FungiDB:SPCC550.09; -.
DR HOGENOM; CLU_499821_0_0_1; -.
DR InParanoid; O59807; -.
DR OMA; WIDDKWS; -.
DR PRO; PR:O59807; -.
DR Proteomes; UP000002485; Chromosome III.
DR GO; GO:0005737; C:cytoplasm; HDA:PomBase.
DR GO; GO:0005779; C:integral component of peroxisomal membrane; IBA:GO_Central.
DR GO; GO:0007031; P:peroxisome organization; ISO:PomBase.
DR InterPro; IPR010482; Peroxin.
DR InterPro; IPR006614; Peroxin/Ferlin.
DR Pfam; PF06398; Pex24p; 1.
DR SMART; SM00694; DysFC; 1.
DR SMART; SM00693; DysFN; 1.
PE 3: Inferred from homology;
KW Glycoprotein; Membrane; Peroxisome; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..535
FT /note="Peroxisomal membrane protein pex32"
FT /id="PRO_0000356187"
FT TOPO_DOM 1..31
FT /note="Peroxisomal"
FT /evidence="ECO:0000250"
FT TRANSMEM 32..52
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 53..262
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
FT TRANSMEM 263..283
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 284..535
FT /note="Peroxisomal"
FT /evidence="ECO:0000250"
FT REGION 87..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 142..194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 323..353
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 482..535
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 101..115
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 142..163
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 177..194
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 336..353
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 492..526
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 374
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 377
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 409
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 418
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 535 AA; 60202 MW; D12AA66C7FD0A0DB CRC64;
MIRAHLFSEP DNSKLWAKST GSDAFDLILK VLLWTAPWYY CLTTLFFTWL IILYPRPTLA
CSVAAWLFWF TSLDTLEPDD RKNTLKASEA VSTSAKTSEE TAKPSETRED GEWNTLKNTL
EADAQNLMSG FQMLQRRWSQ PKTTTLKTEV KEQQASQSPS VEGENEPAGV KSNEATKPSV
TEEKEKNAEQ NKRRERLSIS HIVTELAKKD EVSSESGSNE IVNAKLKNEQ LDSNFTLLDA
YLEPLVHLHE YSRRSNTLFF FYLPIVMSIL IFCLPTQALF IVLSSVFLAW HSPPLQAVLF
CIRRISFFNL LYEKFVIGKT KEPAKPVPQP SSNEPPAPSA ENKQPSVSSP EKKESPATHL
LKVIGSSPYV VHSNHTNNTL TDKESSDPTE KCLYLIEHQR YWVGVGWLNR TLPTDPPNFT
NAGSTDPVAE PTAQLLPPDG LAWIDDKWSI SPWTFTDTFW AQPAKTQFRT AFTRSREWRR
RYRVAPPAEN EKPHTSRTNT ASSLSSTSED QVSTHGSISS AKVTAIPDSN GAEAL
