ID   PEX3_DEBHA              Reviewed;         420 AA.
AC   Q6BK00;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=Peroxisomal biogenesis factor 3;
DE   AltName: Full=Peroxin-3;
GN   Name=PEX3; OrderedLocusNames=DEHA2F26026g;
OS   Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990
OS   / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Debaryomyces.
OX   NCBI_TaxID=284592;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in peroxisome biosynthesis. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Peroxisome membrane {ECO:0000250}; Single-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the peroxin-3 family. {ECO:0000305}.
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DR   EMBL; CR382138; CAG89890.1; -; Genomic_DNA.
DR   RefSeq; XP_461471.1; XM_461471.1.
DR   AlphaFoldDB; Q6BK00; -.
DR   SMR; Q6BK00; -.
DR   STRING; 4959.XP_461471.1; -.
DR   PRIDE; Q6BK00; -.
DR   EnsemblFungi; CAG89890; CAG89890; DEHA2F26026g.
DR   GeneID; 2903482; -.
DR   KEGG; dha:DEHA2F26026g; -.
DR   VEuPathDB; FungiDB:DEHA2F26026g; -.
DR   eggNOG; KOG4444; Eukaryota.
DR   HOGENOM; CLU_017002_0_0_1; -.
DR   InParanoid; Q6BK00; -.
DR   OMA; KQRFIQT; -.
DR   OrthoDB; 891261at2759; -.
DR   Proteomes; UP000000599; Chromosome F.
DR   GO; GO:0005779; C:integral component of peroxisomal membrane; IEA:InterPro.
DR   GO; GO:0007031; P:peroxisome organization; IEA:UniProtKB-KW.
DR   InterPro; IPR006966; Peroxin-3.
DR   PANTHER; PTHR28080; PTHR28080; 1.
DR   Pfam; PF04882; Peroxin-3; 2.
PE   3: Inferred from homology;
KW   Membrane; Peroxisome; Peroxisome biogenesis; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..420
FT                   /note="Peroxisomal biogenesis factor 3"
FT                   /id="PRO_0000208742"
FT   TOPO_DOM        1..16
FT                   /note="Peroxisomal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        17..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        38..420
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   420 AA;  48150 MW;  D140DB9E967FE17D CRC64;
     MPIFSSLNSF LRRHKKKLIV TATLTFSAYF LVNQFIIKKL KNFQNSLRQE LFVKEQIKRR
     FVQTQNDCYL TILALLPVLT QPIINHLPIE LITQALKLKK TNSNPTPQEI SDSLLTTDNL
     TMHQNTNDSS DLSHYMSLSK TELWKLLKIK TLTRTLTLMY SISGLLLLTR LQLNILARRS
     YLESAIILAG GKVNDTETSQ DYFIEQSYLS LSWWLLNKGW LKISDLVEKV VTEKFNTINA
     RTELSINKFD DLLCEMVNEL STNHNQEILN AVFPISYDNL IESLLNTNPE LIKELDIEDS
     IMLKLINETT YLVSNEAFGD ILINMVDSCK STLIENLLLS LDPENAYTNQ EKVIDISNIK
     QFKLANLLAQ LSIQCGVLCD NNNLMNDTFS NELSGNIYMN NLNEIESLDE FSASIYSNFE