ID   PEX6_ASHGO              Reviewed;        1021 AA.
AC   Q74Z13;
DT   31-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=Peroxisomal biogenesis factor 6;
DE   AltName: Full=Peroxin-6;
GN   Name=PEX6; OrderedLocusNames=AGR394W;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: Involved in peroxisome biosynthesis. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the AAA ATPase family. {ECO:0000305}.
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DR   EMBL; AE016820; AAS54884.1; -; Genomic_DNA.
DR   RefSeq; NP_987060.1; NM_212122.1.
DR   AlphaFoldDB; Q74Z13; -.
DR   SMR; Q74Z13; -.
DR   STRING; 33169.AAS54884; -.
DR   EnsemblFungi; AAS54884; AAS54884; AGOS_AGR394W.
DR   GeneID; 4623364; -.
DR   KEGG; ago:AGOS_AGR394W; -.
DR   eggNOG; KOG0736; Eukaryota.
DR   HOGENOM; CLU_000688_0_4_1; -.
DR   InParanoid; Q74Z13; -.
DR   OMA; DSMLNAM; -.
DR   Proteomes; UP000000591; Chromosome VII.
DR   GO; GO:1904949; C:ATPase complex; IEA:EnsemblFungi.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0005778; C:peroxisomal membrane; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IBA:GO_Central.
DR   GO; GO:0016558; P:protein import into peroxisome matrix; IBA:GO_Central.
DR   GO; GO:0016562; P:protein import into peroxisome matrix, receptor recycling; IEA:EnsemblFungi.
DR   GO; GO:0043335; P:protein unfolding; IEA:EnsemblFungi.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR003960; ATPase_AAA_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00004; AAA; 2.
DR   SMART; SM00382; AAA; 2.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   PROSITE; PS00674; AAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Nucleotide-binding; Peroxisome biogenesis; Reference proteome.
FT   CHAIN           1..1021
FT                   /note="Peroxisomal biogenesis factor 6"
FT                   /id="PRO_0000084610"
FT   BINDING         763..770
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   1021 AA;  113501 MW;  71E3FBB4F5CAD1FB CRC64;
     MVIANLVFSA SGTSLASVSR ELYCTLFGPA PDELKHEFYV SVQLPSYSRH AKTYVVQSTL
     NETLEGQVVQ LPSKIEDVPL DTPLIDLCKV EAVRERPPVL ESVTIEVHGS LYEELTKLSE
     EDQLRFLQIR GDLRDCGTVV RAGQKLFVPW CQILDCVPYY QGLIDLQRTR ILLLKGTDAM
     ESCHLRKGLE DLKLRPNEGP TKELRIMLRC LEQPIERALL VPAADTDDDD SLFVFASAAV
     LLRLGVTSGA RVTLSDGATS RIAKVFVLLS PNHFDSDAIY ATPRLVVNFA EADKVVVSKY
     EGEMAELPVA SSVSISRVGS WENSQMVYQK IILNNLTNFI TAKQRIFYKD DLVPVTFDSD
     FSAMFSDQLN EFSVDYHDDS LVWFKIDTVK LNDDIPCEGA FRIDSKVTKL VTCNVSSSPP
     PPLSKCDYVS YYGLEPCFGY DRRVFDYAKR FHDIITTSRK CFQHGMNVGT TVMLHSSSVS
     VGKTTLVRST CRELGIHLIE IDLLQLDPHM NSSNSTVNIV ALIRAKIENV LPHTAPSVVY
     LAHLEGVLEK EDQISDPASL KAAKSMGIEL AKLFTDYTEL YPGTVFVCST DALDVVPEAI
     RSKTKFEIEV PVPTETQRVE IFSWYLSPDV LNFNASQQFA MDHDVTISRL ALQSAGLTPI
     DIRSIVESAK VCCYQRSKEK QHMLWQGGYR YINSADLSAA INKARDEFSD SIGAPKIPNV
     FWEDIGGLEM VKGEILDTID MPLKFPELFA SGMKKRSGIL FYGPPGTGKT LLAKAVATNF
     SLNFFSVKGP ELLNMYIGES EANVRRVFQR ARDAKPCVIF FDELDSVAPK RGNQGDSGGV
     MDRIVSQLLA ELDGLSTGGD GLFVIGATNR PDLLDEALLR PGRFDKLLYL GISDTNEKQA
     NILRALTRKF TLDPDVSLDD LAASCPFTYT GADFYALCSD AMLNAMTRIA GNVDEKVASY
     NRAHNKNYSV RQWFDVIATA EDTSITVCMQ DFVKAQRELV PSVSEGELNH YLAIRDNFES
     S