ID   PEX6_KLULA              Reviewed;        1000 AA.
AC   Q6CPV1;
DT   31-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=Peroxisomal biogenesis factor 6;
DE   AltName: Full=Peroxin-6;
GN   Name=PEX6; OrderedLocusNames=KLLA0E02002g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in peroxisome biosynthesis. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the AAA ATPase family. {ECO:0000305}.
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DR   EMBL; CR382125; CAG99125.1; -; Genomic_DNA.
DR   RefSeq; XP_454038.1; XM_454038.1.
DR   AlphaFoldDB; Q6CPV1; -.
DR   SMR; Q6CPV1; -.
DR   STRING; 28985.XP_454038.1; -.
DR   EnsemblFungi; CAG99125; CAG99125; KLLA0_E02003g.
DR   GeneID; 2893978; -.
DR   KEGG; kla:KLLA0_E02003g; -.
DR   eggNOG; KOG0736; Eukaryota.
DR   HOGENOM; CLU_000688_0_4_1; -.
DR   InParanoid; Q6CPV1; -.
DR   OMA; DSMLNAM; -.
DR   Proteomes; UP000000598; Chromosome E.
DR   GO; GO:1904949; C:ATPase complex; IEA:EnsemblFungi.
DR   GO; GO:0005829; C:cytosol; IEA:EnsemblFungi.
DR   GO; GO:0005777; C:peroxisome; IEA:EnsemblFungi.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:EnsemblFungi.
DR   GO; GO:0016562; P:protein import into peroxisome matrix, receptor recycling; IEA:EnsemblFungi.
DR   GO; GO:0043335; P:protein unfolding; IEA:EnsemblFungi.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR003960; ATPase_AAA_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00004; AAA; 2.
DR   SMART; SM00382; AAA; 2.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   PROSITE; PS00674; AAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Nucleotide-binding; Peroxisome biogenesis; Reference proteome.
FT   CHAIN           1..1000
FT                   /note="Peroxisomal biogenesis factor 6"
FT                   /id="PRO_0000084614"
FT   BINDING         742..749
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   1000 AA;  112961 MW;  C35DA6F2B0C448D3 CRC64;
     MVIASLESTH AISTSIVLSS DLWTEFYGTE SVSSASPNYV KLTLPSYNKW HHQALISHCD
     NDDSLPFGSA GLPTNFIKQS QVRPMFSSIE IEPYVQQLPN LDNLVLSLNP DLFNELNQLS
     KEEQRKFLTL RFNLLFGITV LNVNQVVYPA FCKVTSSSND FGILTDQTQI VLVPDSNVVE
     QSRSNDEFTE FDHLFSLHVK IQSLLDPVPV EFLSPPQPDT TDNDLFAFVQ PNILLQLGVP
     SGTFVRVIAE EQEMLVQLFV LFAPNEYECD SLYVSPRVRY VFMNHARVII QRPNLALNRF
     SVSNAVTLSR IGCQINAQRR YQDIISHHLA LYFSEKQRIV KVGDLIPITF DSNYASMFTD
     DIRSGQHDTL VWFKVEEIES DSNEEYHIID SSITRLSTVK ITSRELMPKS ICDYDRFYNL
     SPLFHYDEDA FPFAKRLKDI LNTAIKCSAR NVNVGTSIML HSSSPNVGKT MLTRSVCAEL
     GFHLIHVDCL SLTSNSNTSD ATNKTIGYIR AKIETIISYV EKVVIFLSHL ETILEDEQNQ
     QDNTSSKMAR QMNVEMADLI EEYTTKYKGT VFVGSTNDID NIPAIVRSRI KFEIDVPVPT
     EKQRLQMFRW YFDPYVLNSQ TPKLRSLISH NVPLQTVSVQ SAGLTPMDIR SIVKAVKYKC
     YQRLKQNDLL IDMTDITAVI NIARDRFSDS IGAPKIPNVT WDDIGGMDVV KGEIMDTIDM
     PLKHPELFSS GMKKRSGILF YGPPGTGKTL LAKAIASNFS LNFFSVKGPE LLNMYIGESE
     ANVRRVFQKA RDAKPCVIFF DELDSVAPKR GNQGDSGGVM DRIVSQLLAE LDGMSSGGDG
     VFVIGATNRP DLLDEALLRP GRFDKMLYLG ISDTDKKQAN IIKALTRKFT LESGIDILDI
     AKKCPFNYTG ADFYALCSDA LLNAMTRVAG EVDEKWEKYN MENKKNISLR YWFDNVANEN
     DLKVVVKLQD FELAQQNLIP SVSEDELRHY LRLKSSFESQ