ID   PEX6_PENCH              Reviewed;        1459 AA.
AC   Q9HG03;
DT   31-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 67.
DE   RecName: Full=Peroxisomal biogenesis factor 6;
DE   AltName: Full=Peroxin-6;
GN   Name=pex6;
OS   Penicillium chrysogenum (Penicillium notatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium;
OC   Penicillium chrysogenum species complex.
OX   NCBI_TaxID=5076;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=10968639; DOI=10.1007/s002530000378;
RA   Kiel J.A.K.W., Hilbrands R.E., Bovenberg R.A., Veenhuis M.;
RT   "Isolation of Penicillium chrysogenum PEX1 and PEX6 encoding AAA proteins
RT   involved in peroxisome biogenesis.";
RL   Appl. Microbiol. Biotechnol. 54:238-242(2000).
CC   -!- FUNCTION: Involved in peroxisome biosynthesis. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the AAA ATPase family. {ECO:0000305}.
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DR   EMBL; AF233277; AAG09749.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q9HG03; -.
DR   SMR; Q9HG03; -.
DR   PhylomeDB; Q9HG03; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0007031; P:peroxisome organization; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR003960; ATPase_AAA_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00004; AAA; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   PROSITE; PS00674; AAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Nucleotide-binding; Peroxisome biogenesis.
FT   CHAIN           1..1459
FT                   /note="Peroxisomal biogenesis factor 6"
FT                   /id="PRO_0000084616"
FT   REGION          1..28
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          316..410
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1357..1459
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        330..356
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        368..382
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1386..1404
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1422..1439
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1440..1459
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         1070..1077
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   1459 AA;  157054 MW;  C5219F4DBA6E49B9 CRC64;
     MDFEQYGQSS QQPRQRRRRA GKRRLNNKTP IAARLALDPQ LRGKVGILSE DLANDLFQQQ
     ALQDVTTSDD GVLYVAIAPH TPTYTSVEDQ AWTILPVRIQ PTERSPVAMS HSTVLFPESA
     DSLQPFLQAL GKVDSSRNSL QAHRSVEIRI LDVAPIHLDT IFVTVERHLL RNHDDVQTKF
     GGGFTNAQGP NGLWGKTGKS VEAKKYSKRA AADAEQRLTA AVREALGAQR IVHTGDVLPL
     PLPSHPITYA PPPPARISFC EPVSQGLLMS TTKIVLVQAR PQGIRAQQTM PSRSALLKQV
     AEDEADDTSN EQFYSAAEDK PGESGTEMEV TSAAEESETE GSAGSMSDSS DDSLEDMISL
     SAPELPQPPS GVMSSLTSAT PRAGGRRSDG IHTPGSVASN FTSATMRPGR GGGKTFKVEG
     LLQQVPNEVL HPRPRDDEDV DSFVFVDIST LAKIGCFSGD WVRIEAAEEP QLNMFASLKF
     GSFNDSPEDS GDWRPVKIFG LSGLPSSKPR YAINHSGERR PSISQRPPTR LTPSVFVPPL
     LLGNIENPKY LRISPMTFAT PNGSSKPGIL QHMKNTAAKN PPLAKEVTLL KVSTPLSMDR
     VLQPALFAGL KQYFESRRRI LKSGDLVGIS VDEGLGRAVF SGTGSGDSAS QEEDITIRLG
     QGANATNAGT RKIGVAWFRV GQVAPTTVEE LEETGEDQWG GVAVLDPATT RMVQAGSDVS
     RVPGVLGNGW EYWLGVKTIP KTVHDAPTPH GIVADPPQSV IPPLQQRIRD LMSAATSPRA
     IQLGMKPVFI LLRSQQRHIG KATVATRACS DIGIHTFPID AYDILTEGGA NGGDVKTEAY
     LKARAERAFH CGANCTALLI RHIEVLTADR IVTAMSDILN DARVVIATTT DVETIPEGIR
     SLITHEFEMG APEEKEREGI LQNAVTERGI RLSADVDLGS IALKTAALVA GDLVDVVERA
     AGARTARLES LAEASKKISG SEVFVRDVLL AGGDGARGVT KADFDAAVEA ARKNFADSIG
     APKIPNVGWD DVGGLTNVKD ALVETIQLPL ERPELFAKGM KKRSGILFYG PPGTGKTLLA
     KAIATEFSLN FFSVKGPELL NMYIGESEAN VRRVFQRARD ARPCVVFFDE LDSVAPKRGN
     QGDSGGVMDR IVSQLLAELD GMNGGEENSG GVFVIGATNR PDLLDTALLR PGRFDKMLYL
     GVSDTHRKQA TILEALTRKF ALHPDVSLDR VAEQLPLTYT GADLYALCSD AMLKAITRKA
     TAVDEKINAL PNGPVSTAWF FDHLATKEDV NVMVTEEDFL SAQGELVPSV SAKELEHFER
     IRQTFEAVDK SKQDPAAAAP QTIAEAMEAF SLGGSAIPEE APTINGDSLT PGGIHGRIKG
     LNRWPGNPVR STSGQSTTSS KGKGKSVSKK GKSRTGAESD GSVDGDDEDM ADANSKEDED
     EDDYVVRTDH LRNPMEEVE