ID   PEX6_PICAN              Reviewed;        1135 AA.
AC   Q9UVU5;
DT   31-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   03-AUG-2022, entry version 64.
DE   RecName: Full=Peroxisomal biogenesis factor 6;
DE   AltName: Full=Peroxin-6;
GN   Name=PEX6;
OS   Pichia angusta (Yeast) (Hansenula polymorpha).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Pichiaceae; Ogataea.
OX   NCBI_TaxID=870730;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND INTERACTION WITH PEX1.
RC   STRAIN=ATCC 34438 / CBS 4732 / DSM 70277 / JCM 3621 / NBRC 1476 / NRRL
RC   Y-5445;
RX   PubMed=10455230;
RX   DOI=10.1002/(sici)1097-0061(199908)15:11<1059::aid-yea434>3.0.co;2-i;
RA   Kiel J.A.K.W., Hilbrands R.E., van der Klei I.J., Rasmussen S.W.,
RA   Salomons F.A., van der Heide M., Faber K.N., Cregg J.M., Veenhuis M.;
RT   "Hansenula polymorpha Pex1p and Pex6p are peroxisome-associated AAA
RT   proteins that functionally and physically interact.";
RL   Yeast 15:1059-1078(1999).
CC   -!- FUNCTION: Involved in peroxisome biosynthesis. {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with PEX1. {ECO:0000269|PubMed:10455230}.
CC   -!- SIMILARITY: Belongs to the AAA ATPase family. {ECO:0000305}.
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DR   EMBL; AF129874; AAD52812.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q9UVU5; -.
DR   SMR; Q9UVU5; -.
DR   PRIDE; Q9UVU5; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0007031; P:peroxisome organization; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR003960; ATPase_AAA_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00004; AAA; 2.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   PROSITE; PS00674; AAA; 1.
PE   1: Evidence at protein level;
KW   ATP-binding; Nucleotide-binding; Peroxisome biogenesis.
FT   CHAIN           1..1135
FT                   /note="Peroxisomal biogenesis factor 6"
FT                   /id="PRO_0000084617"
FT   BINDING         853..860
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   1135 AA;  126063 MW;  D478268E959780F6 CRC64;
     MPGLVEAPVE PYARPVRTLV QLALDPDDGL EYVSLNSQVY ELIYGDLSDN KTRFVSLQLL
     GSPLFVEYQL FRAELDSELP QDSIELHSPR LSSKYGSDFT LEKCIVVPVT KVLSLTSVIM
     SFPHDVYRLI EGISKERLLE IVASERGSDA GHILIRKTDF LKTLHGEVIH CEPVDQGFLS
     SDTNLVIVKQ EGLKRGVNGN VNGSHPDPSE IPVSTPVDFS VSHLGLGDLT FDDTSIFSNL
     TLQPLELQIG FLKYSMLMDC THILESSHEF DHEDDQLFAC VCSSVLQKLG CFSGDLVQIQ
     TCDCGAGIVC ACDKSARRKI TIRVFSLADP NDFDPEKLYL SPIFLNSIGN PRIVFVKRLA
     SQRPNGDFVC EKLENHVPVA KEVVIARVAS PITLDRTMQH LFLSNLKTYF ESKHRVIVKD
     QYIPVPIDTV LAKSLFSTYN ASGDETQPEI IPQGIPNELA WFKITDGTTE TDDGKSLVAG
     KQYIIDPAKT RMIQSGVCSD KVPLSDGISY SQLRDYFELP RQFAYPCLRI SNVLTFPYAN
     QLRKIVSVAF RIRDNSYSRS RVQTTILLSS MARCVGKATL VRRIATEFGA NLLELDAYDL
     LNQASVSKTI GTIRGKSDRV VDSCCSVILY IRHIEALAKK PDPNQQQKDS MSLRLAELID
     EYTSKGAIFI GSTNDADAIS ELIRSKFKFD ISINVPTEPE RKLILTDLLD DMKTKDKTPV
     VLRPDVSLDT LALQSAGLTA NDLVSIVDNT ITIAIERLER LSEEQKVNWD QLLSFNGGRI
     KLTPEDFETS INDARNKFSD MIGAPRIPDV KWEDVGGLDV VKDEILDTIE MPLKHPELFS
     KGMKKRSGIL FYGPPGTGKT LLAKAIATNF ALNFFSVKGP ELLNMYIGES EANVRRVFQK
     ARDAKPCVIF FDELDSVAPK RGNQGDSGGV MDRIVSQLLA ELDGMSGAEG GDGVFVVGAT
     NRPDLLDEAL LRPGRFDKML YLGIADTHEK QAKIIQALTR KFQLDPSVDL GRIAETCPFT
     YTGADFYALC SDAMLNAMTR TAGAVEKKIN EYNCNREEGD KISTRFWFDN IAKPEDTQVL
     VKSEDFAKAR DELVPSVSAE ELQHYLSVRE NFEGGKTQDV MHTVPDGADI IISHD