PF08_PLAF7
ID PF08_PLAF7 Reviewed; 262 AA.
AC C0H4K2;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 29-SEP-2021, sequence version 2.
DT 25-MAY-2022, entry version 50.
DE RecName: Full=Uncharacterized protein;
GN ORFNames=MAL7P1.13, PF3D7_0703600;
OS Plasmodium falciparum (isolate 3D7).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=36329;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3D7;
RX PubMed=12368864; DOI=10.1038/nature01097;
RA Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.D.,
RA Eisen J.A., Rutherford K.M., Salzberg S.L., Craig A., Kyes S., Chan M.-S.,
RA Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M.,
RA Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.A.,
RA Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I.,
RA Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J.,
RA Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.G.;
RT "Genome sequence of the human malaria parasite Plasmodium falciparum.";
RL Nature 419:498-511(2002).
RN [2] {ECO:0000312|EMBL:CAX64022.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3D7;
RX PubMed=12368867; DOI=10.1038/nature01095;
RA Hall N., Pain A., Berriman M., Churcher C.M., Harris B., Harris D.,
RA Mungall K.L., Bowman S., Atkin R., Baker S., Barron A., Brooks K.,
RA Buckee C.O., Burrows C., Cherevach I., Chillingworth C., Chillingworth T.,
RA Christodoulou Z., Clark L., Clark R., Corton C., Cronin A., Davies R.M.,
RA Davis P., Dear P., Dearden F., Doggett J., Feltwell T., Goble A.,
RA Goodhead I., Gwilliam R., Hamlin N., Hance Z., Harper D., Hauser H.,
RA Hornsby T., Holroyd S., Horrocks P., Humphray S., Jagels K., James K.D.,
RA Johnson D., Kerhornou A., Knights A., Konfortov B., Kyes S., Larke N.,
RA Lawson D., Lennard N., Line A., Maddison M., Mclean J., Mooney P.,
RA Moule S., Murphy L., Oliver K., Ormond D., Price C., Quail M.A.,
RA Rabbinowitsch E., Rajandream M.A., Rutter S., Rutherford K.M., Sanders M.,
RA Simmonds M., Seeger K., Sharp S., Smith R., Squares R., Squares S.,
RA Stevens K., Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.R.,
RA Sulston J.E., Craig A., Newbold C., Barrell B.G.;
RT "Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.";
RL Nature 419:527-531(2002).
RN [3] {ECO:0000305}
RP SYNTHESIS OF 69-99, AND POSSIBLE CANDIDATE MALARIA EPITOPE.
RX PubMed=17653272; DOI=10.1371/journal.pone.0000645;
RA Villard V., Agak G.W., Frank G., Jafarshad A., Servis C., Nebie I.,
RA Sirima S.B., Felger I., Arevalo-Herrera M., Herrera S., Heitz F.,
RA Baecker V., Druilhe P., Kajava A.V., Corradin G.;
RT "Rapid identification of malaria vaccine candidates based on alpha-helical
RT coiled coil protein motif.";
RL PLoS ONE 2:E645-E645(2007).
CC -!- BIOTECHNOLOGY: Possible candidate for an effective malaria vaccine as
CC determined by epitope response in sera. {ECO:0000269|PubMed:17653272}.
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DR EMBL; AL844506; CAX64022.1; -; Genomic_DNA.
DR RefSeq; XP_002808749.1; XM_002808703.1.
DR AlphaFoldDB; C0H4K2; -.
DR SMR; C0H4K2; -.
DR BioGRID; 1210009; 4.
DR STRING; 5833.MAL7P1.13; -.
DR PRIDE; C0H4K2; -.
DR EnsemblProtists; CAX64022; CAX64022; PF3D7_0703600.
DR GeneID; 2655153; -.
DR KEGG; pfa:PF3D7_0703600; -.
DR InParanoid; C0H4K2; -.
DR PhylomeDB; C0H4K2; -.
DR Proteomes; UP000001450; Chromosome 7.
DR InterPro; IPR038835; Giardin_beta-like.
DR PANTHER; PTHR37027; PTHR37027; 1.
PE 1: Evidence at protein level;
KW Coiled coil; Merozoite; Reference proteome.
FT CHAIN 1..262
FT /note="Uncharacterized protein"
FT /id="PRO_0000374062"
FT COILED 41..118
FT /evidence="ECO:0000255"
SQ SEQUENCE 262 AA; 31438 MW; 8486C1BB2ABF7766 CRC64;
MEELNKSGIY SKQFSLSQNK HNSERLQRLE KRLSGLHFSI ELQKNEKIDK LNEKINSLEE
KLIEMHENSN KTFEKLNEKL NDIRNDVTNY KNELEEFKND HKKKLQLLEE KAEDFINKEK
EDWSRLKIKL VKDFQHKAAL LKEEMVEEYG LIEEKEDSLR KYYDCEINNI KSIIQNEISE
RIKTEKIILS DVDDKINEIM KIIRNEKTTR ETYSENLVSL IEQYFSRIKK EIDMERLERE
DTEETLVHLM EEALDKIGIP LA