ID   PF12P_PLABA             Reviewed;         295 AA.
AC   Q4Z5T0;
DT   18-SEP-2013, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2005, sequence version 1.
DT   25-MAY-2022, entry version 49.
DE   RecName: Full=Surface protein P12p;
DE   Flags: Precursor;
GN   ORFNames=PB000527.00.0;
OS   Plasmodium berghei (strain Anka).
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Vinckeia).
OX   NCBI_TaxID=5823;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ANKA;
RX   PubMed=15637271; DOI=10.1126/science.1103717;
RA   Hall N., Karras M., Raine J.D., Carlton J.M., Kooij T.W.A., Berriman M.,
RA   Florens L., Janssen C.S., Pain A., Christophides G.K., James K.,
RA   Rutherford K., Harris B., Harris D., Churcher C.M., Quail M.A., Ormond D.,
RA   Doggett J., Trueman H.E., Mendoza J., Bidwell S.L., Rajandream M.A.,
RA   Carucci D.J., Yates J.R. III, Kafatos F.C., Janse C.J., Barrell B.G.,
RA   Turner C.M.R., Waters A.P., Sinden R.S.;
RT   "A comprehensive survey of the Plasmodium life cycle by genomic,
RT   transcriptomic, and proteomic analyses.";
RL   Science 307:82-86(2005).
CC   -!- SUBCELLULAR LOCATION: Cell surface {ECO:0000250}. Cell membrane
CC       {ECO:0000250}.
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DR   EMBL; CAAI01000395; CAH94268.1; -; Genomic_DNA.
DR   RefSeq; XP_678959.1; XM_673867.1.
DR   AlphaFoldDB; Q4Z5T0; -.
DR   SMR; Q4Z5T0; -.
DR   eggNOG; ENOG502TMXB; Eukaryota.
DR   InParanoid; Q4Z5T0; -.
DR   GO; GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.60.40.2860; -; 2.
DR   InterPro; IPR010884; 6_CYS_dom.
DR   InterPro; IPR038160; 6_CYS_dom_sf.
DR   Pfam; PF07422; s48_45; 2.
DR   SMART; SM00970; s48_45; 2.
DR   PROSITE; PS51701; 6_CYS; 2.
PE   3: Inferred from homology;
KW   Cell membrane; Disulfide bond; Glycoprotein; Malaria; Membrane; Repeat;
KW   Signal.
FT   SIGNAL          1..?
FT                   /evidence="ECO:0000255"
FT   CHAIN           ?..295
FT                   /note="Surface protein P12p"
FT                   /id="PRO_0000423569"
FT   DOMAIN          4..151
FT                   /note="6-Cys 1"
FT   DOMAIN          152..294
FT                   /note="6-Cys 2"
FT   CARBOHYD        229
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        247
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        281
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        8..43
FT                   /evidence="ECO:0000250"
FT   DISULFID        57..127
FT                   /evidence="ECO:0000250"
FT   DISULFID        76..125
FT                   /evidence="ECO:0000250"
FT   DISULFID        156..191
FT                   /evidence="ECO:0000250"
FT   DISULFID        206..268
FT                   /evidence="ECO:0000250"
FT   DISULFID        217..266
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   295 AA;  33818 MW;  88CF5066DFCC1749 CRC64;
     MIQNIEICDF SRGSLDVALM NNKILIDNNL KEENYNDNNI KHCVIFTKGL EIFTFICPKG
     NNNDNYKGVE IRPEQCFEKV RINGKEENLK DILKGVVIEK KETDTEIIRK ALIPPTIYQD
     MSFECSCDNS LTIKDNYIGA RGIMKVHLKK NIIFGCDFNY DSNEPKLSNG KSAFAQFYDK
     QVVDSNKNII CNTQVNNKEV YLGLVCPEGY GMYPENCFEN VLFEKKVINI TELIKHDVKL
     HIEKNKNISF ASFILNPNEN PKSFSCHCIK NNDNSFPLIA NITFPIMNLI LLISM