ID   PFD1_CAEBR              Reviewed;         117 AA.
AC   Q61SU8; A8X131;
DT   18-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Probable prefoldin subunit 1;
GN   Name=pfd-1; ORFNames=CBG06021;
OS   Caenorhabditis briggsae.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6238;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF16;
RX   PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA   Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA   Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA   Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA   Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA   Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA   Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA   Durbin R.M., Waterston R.H.;
RT   "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT   genomics.";
RL   PLoS Biol. 1:166-192(2003).
CC   -!- FUNCTION: Binds specifically to cytosolic chaperonin (c-CPN) and
CC       transfers target proteins to it. Binds to nascent polypeptide chain and
CC       promotes folding in an environment in which there are many competing
CC       pathways for nonnative proteins. Has a role in gonadogenesis (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Heterohexamer of two PFD-alpha type and four PFD-beta type
CC       subunits. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the prefoldin subunit beta family.
CC       {ECO:0000305}.
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DR   EMBL; HE600909; CAP26341.3; -; Genomic_DNA.
DR   RefSeq; XP_002633292.1; XM_002633246.1.
DR   AlphaFoldDB; Q61SU8; -.
DR   SMR; Q61SU8; -.
DR   STRING; 6238.CBG06021; -.
DR   EnsemblMetazoa; CBG06021.1; CBG06021.1; WBGene00028367.
DR   GeneID; 8575289; -.
DR   KEGG; cbr:CBG_06021; -.
DR   CTD; 8575289; -.
DR   WormBase; CBG06021; CBP01634; WBGene00028367; Cbr-pfd-1.
DR   eggNOG; KOG3501; Eukaryota.
DR   HOGENOM; CLU_122140_4_0_1; -.
DR   InParanoid; Q61SU8; -.
DR   OMA; QKMRISE; -.
DR   OrthoDB; 1492856at2759; -.
DR   Proteomes; UP000008549; Chromosome IV.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0016272; C:prefoldin complex; IEA:InterPro.
DR   GO; GO:0044183; F:protein folding chaperone; IBA:GO_Central.
DR   GO; GO:0051082; F:unfolded protein binding; IBA:GO_Central.
DR   GO; GO:0008406; P:gonad development; ISS:UniProtKB.
DR   GO; GO:0006457; P:protein folding; IBA:GO_Central.
DR   Gene3D; 1.10.287.370; -; 1.
DR   InterPro; IPR002777; PFD_beta-like.
DR   InterPro; IPR009053; Prefoldin.
DR   Pfam; PF01920; Prefoldin_2; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Reference proteome.
FT   CHAIN           1..117
FT                   /note="Probable prefoldin subunit 1"
FT                   /id="PRO_0000232449"
SQ   SEQUENCE   117 AA;  13831 MW;  D22B3E78F6902C36 CRC64;
     MADEEISKAF RDLQFKTNET RMRIVQGEQN KKVNHQKMRI SESTKRNLIG LNEDLKYYRS
     VGRMFLLTDK ASEIARHETE AKQSKDKIEA IDKQKEYLEK GLVEAESNLR ELIQSRR