ID   PFD4_CAEBR              Reviewed;         126 AA.
AC   A8X0Z1;
DT   23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 1.
DT   03-AUG-2022, entry version 63.
DE   RecName: Full=Probable prefoldin subunit 4 {ECO:0000250|UniProtKB:Q17435};
GN   Name=pfd-4 {ECO:0000312|EMBL:CAP26301.1}; Synonyms=tag-317;
GN   ORFNames=CBG06071;
OS   Caenorhabditis briggsae.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6238;
RN   [1] {ECO:0000312|EMBL:CAP26301.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF16 {ECO:0000312|EMBL:CAP26301.1};
RX   PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA   Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA   Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA   Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA   Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA   Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA   Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA   Durbin R.M., Waterston R.H.;
RT   "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT   genomics.";
RL   PLoS Biol. 1:166-192(2003).
CC   -!- FUNCTION: Binds specifically to cytosolic chaperonin (c-CPN) and
CC       transfers target proteins to it. Binds to nascent polypeptide chain and
CC       promotes folding in an environment in which there are many competing
CC       pathways for nonnative proteins. Appears to play a non-essential role
CC       (By similarity). {ECO:0000250|UniProtKB:Q17435,
CC       ECO:0000250|UniProtKB:Q9NQP4}.
CC   -!- SUBUNIT: Heterohexamer of two PFD-alpha type and four PFD-beta type
CC       subunits. {ECO:0000250|UniProtKB:Q9NQP4}.
CC   -!- SIMILARITY: Belongs to the prefoldin subunit beta family.
CC       {ECO:0000255}.
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DR   EMBL; HE600986; CAP26301.1; -; Genomic_DNA.
DR   RefSeq; XP_002633332.1; XM_002633286.1.
DR   AlphaFoldDB; A8X0Z1; -.
DR   SMR; A8X0Z1; -.
DR   STRING; 6238.CBG06071; -.
DR   EnsemblMetazoa; CBG06071.1; CBG06071.1; WBGene00028407.
DR   GeneID; 8575329; -.
DR   KEGG; cbr:CBG_06071; -.
DR   CTD; 8575329; -.
DR   WormBase; CBG06071; CBP07222; WBGene00028407; Cbr-pfd-4.
DR   eggNOG; KOG1760; Eukaryota.
DR   HOGENOM; CLU_130032_0_0_1; -.
DR   InParanoid; A8X0Z1; -.
DR   OMA; KFGRAIN; -.
DR   OrthoDB; 1459797at2759; -.
DR   Proteomes; UP000008549; Chromosome IV.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0016272; C:prefoldin complex; IBA:GO_Central.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   InterPro; IPR002777; PFD_beta-like.
DR   InterPro; IPR016661; PFDN4.
DR   PANTHER; PTHR21100; PTHR21100; 1.
DR   Pfam; PF01920; Prefoldin_2; 1.
DR   PIRSF; PIRSF016477; Prefoldin_subunit_4; 1.
PE   3: Inferred from homology;
KW   Chaperone; Reference proteome.
FT   CHAIN           1..126
FT                   /note="Probable prefoldin subunit 4"
FT                   /id="PRO_0000351208"
SQ   SEQUENCE   126 AA;  14129 MW;  CADF94043813886D CRC64;
     MATQAKVSAE DQALLNKFAR SYQLQTQLKA ECKEMKTLVE NINEATDEVL LLDDEDSASI
     PCRIGSCFVH FNSDSLNEHL EAKKASTETV LAEKTNELET ITAEMERIKK VLYGKFGDQI
     NLDAEE