ID   PFD4_CAEEL              Reviewed;         126 AA.
AC   Q17435;
DT   11-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 118.
DE   RecName: Full=Probable prefoldin subunit 4;
GN   Name=pfd-4; Synonyms=tag-317; ORFNames=B0035.4;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Bristol N2;
RA   Kohara Y., Shin-i T., Suzuki Y., Sugano S., Potdevin M., Thierry-Mieg Y.,
RA   Thierry-Mieg D., Thierry-Mieg J.;
RT   "The Caenorhabditis elegans transcriptome project, a complementary view of
RT   the genome.";
RL   Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Binds specifically to cytosolic chaperonin (c-CPN) and
CC       transfers target proteins to it. Binds to nascent polypeptide chain and
CC       promotes folding in an environment in which there are many competing
CC       pathways for nonnative proteins (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Heterohexamer of two PFD-alpha type and four PFD-beta type
CC       subunits. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the prefoldin subunit beta family.
CC       {ECO:0000305}.
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DR   EMBL; Z73102; CAA97410.1; -; Genomic_DNA.
DR   EMBL; AF292051; AAG41147.1; -; mRNA.
DR   PIR; T18655; T18655.
DR   RefSeq; NP_502128.1; NM_069727.6.
DR   AlphaFoldDB; Q17435; -.
DR   SMR; Q17435; -.
DR   BioGRID; 43144; 6.
DR   STRING; 6239.B0035.4; -.
DR   EPD; Q17435; -.
DR   PaxDb; Q17435; -.
DR   PeptideAtlas; Q17435; -.
DR   EnsemblMetazoa; B0035.4.1; B0035.4.1; WBGene00007107.
DR   GeneID; 178045; -.
DR   KEGG; cel:CELE_B0035.4; -.
DR   CTD; 178045; -.
DR   WormBase; B0035.4; CE05162; WBGene00007107; pfd-4.
DR   eggNOG; KOG1760; Eukaryota.
DR   GeneTree; ENSGT00390000006696; -.
DR   HOGENOM; CLU_130032_0_0_1; -.
DR   InParanoid; Q17435; -.
DR   OMA; KFGRAIN; -.
DR   OrthoDB; 1459797at2759; -.
DR   PhylomeDB; Q17435; -.
DR   PRO; PR:Q17435; -.
DR   Proteomes; UP000001940; Chromosome IV.
DR   Bgee; WBGene00007107; Expressed in embryo and 3 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0016272; C:prefoldin complex; IBA:GO_Central.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   InterPro; IPR002777; PFD_beta-like.
DR   InterPro; IPR016661; PFDN4.
DR   PANTHER; PTHR21100; PTHR21100; 1.
DR   Pfam; PF01920; Prefoldin_2; 1.
DR   PIRSF; PIRSF016477; Prefoldin_subunit_4; 1.
PE   2: Evidence at transcript level;
KW   Chaperone; Reference proteome.
FT   CHAIN           1..126
FT                   /note="Probable prefoldin subunit 4"
FT                   /id="PRO_0000124843"
SQ   SEQUENCE   126 AA;  14032 MW;  22D8B5B370AB4DE8 CRC64;
     MPEHTKVSAE DQALLNKFAR SYQTQTQLKA DVKEAKTLID NINEASDEIL LLDDEDSASI
     PCRIGSCFVH FNGDSLNEHL EGKKTTAEKV LSEKTSELDA ISADMEQIKK VLYAKFGDQI
     NLDAEE