ID   PFD5_CAEBR              Reviewed;         154 AA.
AC   A8XPL7;
DT   13-JUL-2010, integrated into UniProtKB/Swiss-Prot.
DT   16-DEC-2008, sequence version 2.
DT   25-MAY-2022, entry version 62.
DE   RecName: Full=Probable prefoldin subunit 5 {ECO:0000250|UniProtKB:Q21993};
GN   Name=pfd-5 {ECO:0000312|EMBL:CAP34538.2}; ORFNames=CBG16620;
OS   Caenorhabditis briggsae.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6238;
RN   [1] {ECO:0000312|EMBL:CAP34538.2}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF16;
RX   PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA   Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA   Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA   Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA   Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA   Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA   Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA   Durbin R.M., Waterston R.H.;
RT   "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT   genomics.";
RL   PLoS Biol. 1:166-192(2003).
CC   -!- FUNCTION: Binds specifically to cytosolic chaperonin (c-CPN) and
CC       transfers target proteins to it. Binds to nascent polypeptide chain and
CC       promotes folding in an environment in which there are many competing
CC       pathways for nonnative proteins (By similarity).
CC       {ECO:0000250|UniProtKB:Q99471}.
CC   -!- SUBUNIT: Heterohexamer of two PFD-alpha type and four PFD-beta type
CC       subunits. {ECO:0000250|UniProtKB:Q99471}.
CC   -!- SIMILARITY: Belongs to the prefoldin subunit alpha family.
CC       {ECO:0000255}.
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DR   EMBL; HE600949; CAP34538.2; -; Genomic_DNA.
DR   AlphaFoldDB; A8XPL7; -.
DR   SMR; A8XPL7; -.
DR   STRING; 6238.CBG16620; -.
DR   EnsemblMetazoa; CBG16620.1; CBG16620.1; WBGene00036507.
DR   WormBase; CBG16620; CBP25483; WBGene00036507; Cbr-pfd-5.
DR   eggNOG; KOG3048; Eukaryota.
DR   HOGENOM; CLU_091867_0_1_1; -.
DR   InParanoid; A8XPL7; -.
DR   OMA; QAKFKAC; -.
DR   OrthoDB; 1449403at2759; -.
DR   Proteomes; UP000008549; Chromosome III.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0016272; C:prefoldin complex; IBA:GO_Central.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR   Gene3D; 1.10.287.370; -; 1.
DR   InterPro; IPR011599; PFD_alpha_archaea.
DR   InterPro; IPR009053; Prefoldin.
DR   InterPro; IPR004127; Prefoldin_subunit_alpha.
DR   PANTHER; PTHR12674; PTHR12674; 1.
DR   Pfam; PF02996; Prefoldin; 1.
DR   TIGRFAMs; TIGR00293; TIGR00293; 1.
PE   3: Inferred from homology;
KW   Chaperone; Reference proteome.
FT   CHAIN           1..154
FT                   /note="Probable prefoldin subunit 5"
FT                   /id="PRO_0000395430"
SQ   SEQUENCE   154 AA;  17413 MW;  BF7978AD9D3A68F4 CRC64;
     MTEEQRGVPL SELSLQQLGE LQKNCEQELT FFQDSFNALK ALLSRNEKSI SALEDVKVGT
     AGHTALIPLS ESLYIRAELS DPNKHMVEIG TGYFVELDRE KAKGIFDRKK EHIAKQVETV
     EGILKEKRRT RAYISDAFQT KVQAQLANMN TQQS