ID   PFD6_CAEBR              Reviewed;         128 AA.
AC   A8Y197;
DT   03-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 1.
DT   03-AUG-2022, entry version 66.
DE   RecName: Full=Probable prefoldin subunit 6 {ECO:0000250|UniProtKB:P52554};
GN   Name=pfd-6 {ECO:0000312|EMBL:CAP38658.1}; ORFNames=CBG21902;
OS   Caenorhabditis briggsae.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6238;
RN   [1] {ECO:0000312|EMBL:CAP38658.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF16 {ECO:0000312|EMBL:CAP38658.1};
RX   PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA   Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA   Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA   Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA   Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA   Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA   Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA   Durbin R.M., Waterston R.H.;
RT   "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT   genomics.";
RL   PLoS Biol. 1:166-192(2003).
CC   -!- FUNCTION: Binds specifically to cytosolic chaperonin (c-CPN) and
CC       transfers target proteins to it. Binds to nascent polypeptide chain and
CC       promotes folding in an environment in which there are many competing
CC       pathways for nonnative proteins. Required for positioning of the
CC       mitotic spindle (By similarity). {ECO:0000250|UniProtKB:O15212,
CC       ECO:0000250|UniProtKB:P52554}.
CC   -!- SUBUNIT: Heterohexamer of two PFD-alpha type and four PFD-beta type
CC       subunits. {ECO:0000250|UniProtKB:O15212}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P52554}.
CC   -!- SIMILARITY: Belongs to the prefoldin subunit beta family.
CC       {ECO:0000255}.
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DR   EMBL; HE600952; CAP38658.1; -; Genomic_DNA.
DR   RefSeq; XP_002629867.1; XM_002629821.1.
DR   AlphaFoldDB; A8Y197; -.
DR   SMR; A8Y197; -.
DR   STRING; 6238.CBG21902; -.
DR   EnsemblMetazoa; CBG21902.1; CBG21902.1; WBGene00040573.
DR   GeneID; 8573033; -.
DR   KEGG; cbr:CBG_21902; -.
DR   CTD; 8573033; -.
DR   WormBase; CBG21902; CBP20255; WBGene00040573; Cbr-pfd-6.
DR   eggNOG; KOG3478; Eukaryota.
DR   HOGENOM; CLU_125172_0_1_1; -.
DR   InParanoid; A8Y197; -.
DR   OMA; VQTEFAQ; -.
DR   OrthoDB; 1559044at2759; -.
DR   Proteomes; UP000008549; Chromosome I.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0016272; C:prefoldin complex; IBA:GO_Central.
DR   GO; GO:0051087; F:chaperone binding; IBA:GO_Central.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   GO; GO:0051131; P:chaperone-mediated protein complex assembly; IBA:GO_Central.
DR   GO; GO:0006457; P:protein folding; IBA:GO_Central.
DR   Gene3D; 1.10.287.370; -; 1.
DR   InterPro; IPR002777; PFD_beta-like.
DR   InterPro; IPR009053; Prefoldin.
DR   Pfam; PF01920; Prefoldin_2; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Reference proteome.
FT   CHAIN           1..128
FT                   /note="Probable prefoldin subunit 6"
FT                   /id="PRO_0000365028"
SQ   SEQUENCE   128 AA;  15031 MW;  F6FBF118E83F8524 CRC64;
     MADMAKFEEE ISKLKTLEKD REKYFSSRQE MEMRLTESKN VKAELDLMDS DSKVYKLMGP
     VLVRQDLEEA RSTVEKRLEF IESEIKRVEA SITDVNKKSI EQRDKVMNMQ KAFQMMATQA
     QQQAAQKK