ID   PFDB_THEVO              Reviewed;         124 AA.
AC   Q979C4;
DT   13-AUG-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2001, sequence version 1.
DT   25-MAY-2022, entry version 94.
DE   RecName: Full=Prefoldin subunit beta;
DE   AltName: Full=GimC subunit beta;
GN   Name=pfdB; OrderedLocusNames=TV1237; ORFNames=TVG1278162;
OS   Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC
OS   15438 / GSS1).
OC   Archaea; Candidatus Thermoplasmatota; Thermoplasmata; Thermoplasmatales;
OC   Thermoplasmataceae; Thermoplasma.
OX   NCBI_TaxID=273116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1;
RX   PubMed=11121031; DOI=10.1073/pnas.97.26.14257;
RA   Kawashima T., Amano N., Koike H., Makino S., Higuchi S., Kawashima-Ohya Y.,
RA   Watanabe K., Yamazaki M., Kanehori K., Kawamoto T., Nunoshiba T.,
RA   Yamamoto Y., Aramaki H., Makino K., Suzuki M.;
RT   "Archaeal adaptation to higher temperatures revealed by genomic sequence of
RT   Thermoplasma volcanium.";
RL   Proc. Natl. Acad. Sci. U.S.A. 97:14257-14262(2000).
CC   -!- FUNCTION: Molecular chaperone capable of stabilizing a range of
CC       proteins. Seems to fulfill an ATP-independent, HSP70-like function in
CC       archaeal de novo protein folding (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Heterohexamer of two alpha and four beta subunits.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the prefoldin subunit beta family.
CC       {ECO:0000305}.
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DR   EMBL; BA000011; BAB60379.1; -; Genomic_DNA.
DR   RefSeq; WP_010917471.1; NC_002689.2.
DR   AlphaFoldDB; Q979C4; -.
DR   SMR; Q979C4; -.
DR   STRING; 273116.14325475; -.
DR   EnsemblBacteria; BAB60379; BAB60379; BAB60379.
DR   GeneID; 1441353; -.
DR   KEGG; tvo:TVG1278162; -.
DR   eggNOG; arCOG01342; Archaea.
DR   HOGENOM; CLU_131909_0_0_2; -.
DR   OMA; PPQVQAM; -.
DR   OrthoDB; 120728at2157; -.
DR   PhylomeDB; Q979C4; -.
DR   Proteomes; UP000001017; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016272; C:prefoldin complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006457; P:protein folding; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.287.370; -; 1.
DR   HAMAP; MF_00307; PfdB; 1.
DR   InterPro; IPR002777; PFD_beta-like.
DR   InterPro; IPR012713; PfdB.
DR   InterPro; IPR009053; Prefoldin.
DR   Pfam; PF01920; Prefoldin_2; 1.
DR   TIGRFAMs; TIGR02338; gimC_beta; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm.
FT   CHAIN           1..124
FT                   /note="Prefoldin subunit beta"
FT                   /id="PRO_0000124873"
SQ   SEQUENCE   124 AA;  14642 MW;  82D0E28968A1993B CRC64;
     MVEPNISSYL QNQLKQAQEL EENIEKIATQ RYQLDLSLKE IEKTLQELNK IDDKTPVYRS
     IGSILYKVDD KKKLIDELEE QLELTKIRIN TLDKQQKSLE EKYKELQAAI RERYNQDNKK
     GAVS