ID   PFM_CHAGB               Reviewed;         222 AA.
AC   P84675; Q2H7A2;
DT   25-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT   20-FEB-2007, sequence version 2.
DT   25-MAY-2022, entry version 43.
DE   RecName: Full=Putative fungistatic metabolite;
GN   ORFNames=CHGG_05463;
OS   Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 /
OS   NRRL 1970) (Soil fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Chaetomiaceae; Chaetomium.
OX   NCBI_TaxID=306901;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970;
RX   PubMed=25720678; DOI=10.1128/genomea.00021-15;
RA   Cuomo C.A., Untereiner W.A., Ma L.-J., Grabherr M., Birren B.W.;
RT   "Draft genome sequence of the cellulolytic fungus Chaetomium globosum.";
RL   Genome Announc. 3:E0002115-E0002115(2015).
RN   [2] {ECO:0000305}
RP   PROTEIN SEQUENCE OF 19-30; 130-140 AND 149-165, AND FUNCTION.
RA   Istifadah N.;
RT   "The endophyte Chaetomium interacts with the pathogen Pyrenophora tritici-
RT   repentis (Dried.) Drechs. in wheat.";
RL   Thesis (2005), University of Sydney, Australia.
CC   -!- FUNCTION: Inhibits the growth of the fungus P.tritici-repentis.
CC       {ECO:0000269|Ref.2}.
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DR   EMBL; CH408031; EAQ88844.1; -; Genomic_DNA.
DR   RefSeq; XP_001221558.1; XM_001221557.1.
DR   AlphaFoldDB; P84675; -.
DR   SMR; P84675; -.
DR   EnsemblFungi; EAQ88844; EAQ88844; CHGG_05463.
DR   GeneID; 4391031; -.
DR   eggNOG; KOG4157; Eukaryota.
DR   HOGENOM; CLU_063916_3_1_1; -.
DR   InParanoid; P84675; -.
DR   OMA; DECHCAT; -.
DR   OrthoDB; 1372432at2759; -.
DR   Proteomes; UP000001056; Unassembled WGS sequence.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
DR   InterPro; IPR002889; WSC_carb-bd.
DR   Pfam; PF01822; WSC; 2.
DR   SMART; SM00321; WSC; 2.
DR   PROSITE; PS51212; WSC; 2.
PE   1: Evidence at protein level;
KW   Antimicrobial; Direct protein sequencing; Fungicide; Reference proteome;
KW   Repeat.
FT   CHAIN           1..222
FT                   /note="Putative fungistatic metabolite"
FT                   /id="PRO_0000058345"
FT   DOMAIN          16..110
FT                   /note="WSC 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00558"
FT   DOMAIN          127..222
FT                   /note="WSC 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00558"
FT   CONFLICT        26
FT                   /note="I -> L (in Ref. 2; AA sequence)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        132
FT                   /note="G -> A (in Ref. 2; AA sequence)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        140
FT                   /note="G -> R (in Ref. 2; AA sequence)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        151
FT                   /note="Missing (in Ref. 2; AA sequence)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   222 AA;  23183 MW;  5BDDCAE27D9186D0 CRC64;
     MQSVLVLAAI VPAALAQTYY GCYTEIPTRA LTGAVPLIDY EAMTLADCEA HCTGFDLWGL
     EYGGECYCGN SLAQGSFPAF STDCTMPCPG DATLTSVCGG PNRLSLYGTS ETAPESLPYP
     HDPPVTTTQY EGCYTEVTEG ARALAGASGF SLTDMTVGGC GGYCRDSGFT WFGLEYSAEC
     YCGSELSVNS TLAAEEDCAM PCSGAAGEVC GGSNRLSVYQ WV