ID   PG46_MYCBO              Reviewed;         778 AA.
AC   P0A691; A0A1R3Y3U9; P71933; X2BLW7;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Uncharacterized PE-PGRS family protein PE_PGRS46;
GN   Name=PE_PGRS46; OrderedLocusNames=BQ2027_MB2667C;
OS   Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=233413;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA   Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA   Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA   Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA   Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT   "The complete genome sequence of Mycobacterium bovis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA   Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA   Robbe-Austerman S., Gordon S.V.;
RT   "Updated reference genome sequence and annotation of Mycobacterium bovis
RT   AF2122/97.";
RL   Genome Announc. 5:E00157-E00157(2017).
CC   -!- SIMILARITY: Belongs to the mycobacterial PE family. PGRS subfamily.
CC       {ECO:0000305}.
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DR   EMBL; LT708304; SIU01285.1; -; Genomic_DNA.
DR   RefSeq; NP_856313.1; NC_002945.3.
DR   RefSeq; WP_009938544.1; NC_002945.4.
DR   AlphaFoldDB; P0A691; -.
DR   EnsemblBacteria; SIU01285; SIU01285; BQ2027_MB2667C.
DR   PATRIC; fig|233413.5.peg.2929; -.
DR   OMA; WTSRCSR; -.
DR   Proteomes; UP000001419; Chromosome.
DR   InterPro; IPR000084; PE-PGRS_N.
DR   Pfam; PF00934; PE; 1.
PE   3: Inferred from homology;
FT   CHAIN           1..778
FT                   /note="Uncharacterized PE-PGRS family protein PE_PGRS46"
FT                   /id="PRO_0000216170"
FT   DOMAIN          1..92
FT                   /note="PE"
FT                   /evidence="ECO:0000255"
FT   REGION          125..163
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          372..510
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          718..778
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        374..407
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   778 AA;  63131 MW;  DAB20FE58E4999E7 CRC64;
     MSFVIAVPEA LTMAASDLAN IGSTINAANA AAALPTTGVV AAAADEVSAA VAALFGSYAQ
     SYQAFGAQLS AFHAQFVQSL TNGARSYVVA EATSAAPLQD LLGVVNAPAQ ALLGRPLIGN
     GANGADGTGA PGGPGGLLLG NGGNGGSGAP GQPGGAGGDA GLIGNGGTGG KGGDGLVGSG
     AAGGVGGRGG WLLGNGGTGG AGGAAGATLV GGTGGVGGAT GLIGSGGFGG AGGAAAGVGT
     TGGVGGSGGV GGVFGNGGFG GAGGLGAAGG VGGAASYFGT GGGGGVGGDG APGGDGGAGP
     LLIGNGGVGG LGGAGAAGGN GGAGGMLLGD GGAGGQGGPA VAGVLGGMPG AGGNGGNANW
     FGSGGAGGQG GTGLAGTNGV NPGSIANPNT GANGTDNSGN GNQTGGNGGP GPAGGVGEAG
     GVGGQGGLGE SLDGNDGTGG KGGAGGTAGT DGGAGGAGGA GGIGETDGSA GGVATGGEGG
     DGATGGVDGG VGGAGGKGGQ GHNTGVGDAF GGDGGIGGDG NGALGAAGGN GGTGGAGGNG
     GRGGMLIGNG GAGGAGGTGG TGGGGAAGFA GGVGGAGGEG LTDGAGTAEG GTGGLGGLGG
     VGGTGGMGGS GGVGGNGGAA GSLIGLGGGG GAGGVGGTGG IGGIGGAGGN GGAGGAGTTT
     GGGATIGGGG GTGGVGGAGG TGGTGGAGGT TGGSGGAGGL IGWAGAAGGT GAGGTGGQGG
     LGGQGGNGGN GGTGATGGQG GDFALGGNGG AGGAGGSPGG SSGIQGNMGP PGTQGADG