ID   PG46_MYCTO              Reviewed;         778 AA.
AC   P9WIE6; L0TD44; P0A690; P71933;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 22.
DE   RecName: Full=Uncharacterized PE-PGRS family protein PE_PGRS46;
GN   Name=PE_PGRS46; OrderedLocusNames=MT2712;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- SIMILARITY: Belongs to the mycobacterial PE family. PGRS subfamily.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAK47026.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE000516; AAK47026.1; ALT_INIT; Genomic_DNA.
DR   PIR; F70963; F70963.
DR   RefSeq; WP_042507591.1; NC_002755.2.
DR   AlphaFoldDB; P9WIE6; -.
DR   EnsemblBacteria; AAK47026; AAK47026; MT2712.
DR   KEGG; mtc:MT2712; -.
DR   HOGENOM; CLU_000167_16_10_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   InterPro; IPR000084; PE-PGRS_N.
DR   Pfam; PF00934; PE; 1.
PE   3: Inferred from homology;
FT   CHAIN           1..778
FT                   /note="Uncharacterized PE-PGRS family protein PE_PGRS46"
FT                   /id="PRO_0000428020"
FT   DOMAIN          1..92
FT                   /note="PE"
FT                   /evidence="ECO:0000255"
FT   REGION          125..163
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          372..510
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          718..778
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        374..407
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   778 AA;  63184 MW;  08C9E540383AD7C5 CRC64;
     MSFVIAVPEA LTMAASDLAN IGSTINAANA AAALPTTGVV AAAADEVSAA LAALFGSYAQ
     SYHAFGAQLS AFHAQFVQSL TNGARSYVVA EATSAAPLQD LLGVVNAPAQ ALLGRPLIGN
     GANGADGTGA PGGPGGLLLG NGGNGGSGAP GQPGGAGGDA GLIGNGGTGG KGGDGLVGSG
     AAGGVGGRGG WLLGNGGTGG AGGAAGATLV GGTGGVGGAT GLIGSGGFGG AGGAAAGVGT
     TGGVGGSGGV GGVFGNGGFG GAGGLGAAGG VGGTASYFGT GGGGGVGGDG APGGDGGAGP
     LLIGNGGVGG LGGAGAAGGN GGAGGMLLGD GGAGGQGGPA VAGVLGGMPG AGGNGGNANW
     FGSGGAGGQG GTGLAGTNGV NPGSIANPNT GANGTDNSGN GNQTGGNGGP GPAGGVGEAG
     GVGGQGGLGE SLDGNDGTGG KGGAGGTAGT DGGAGGAGGA GGIGETDGSA GGVATGGEGG
     DGATGGVDGG VGGAGGKGGQ GHNTGVGDAF GGDGGIGGDG NGALGAAGGN GGTGGAGGNG
     GRGGMLIGNG GAGGAGGTGG TGGGGAAGFA GGVGGAGGEG LTDGAGTAEG GTGGLGGLGG
     VGGTGGMGGS GGVGGNGGAA GSLIGLGGGG GAGGVGGTGG IGGIGGAGGN GGAGGAGTTT
     GGGATIGGGG GTGGVGGAGG TGGTGGAGGT TGGSGGAGGL IGWAGAAGGT GAGGTGGQGG
     LGGQGGNGGN GGTGATGGQG GDFALGGNGG AGGAGGSPGG SSGIQGNMGP PGTQGADG