ID   PG46_MYCTU              Reviewed;         778 AA.
AC   P9WIE7; L0TD44; P0A690; P71933;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 30.
DE   RecName: Full=Uncharacterized PE-PGRS family protein PE_PGRS46;
GN   Name=PE_PGRS46; OrderedLocusNames=Rv2634c; ORFNames=MTCY441.04c;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
CC   -!- SIMILARITY: Belongs to the mycobacterial PE family. PGRS subfamily.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AL123456; CCP45432.1; -; Genomic_DNA.
DR   PIR; F70963; F70963.
DR   RefSeq; WP_009938544.1; NZ_KK339370.1.
DR   RefSeq; YP_177896.1; NC_000962.3.
DR   AlphaFoldDB; P9WIE7; -.
DR   STRING; 83332.Rv2634c; -.
DR   PaxDb; P9WIE7; -.
DR   GeneID; 888573; -.
DR   KEGG; mtu:Rv2634c; -.
DR   PATRIC; fig|83332.111.peg.2939; -.
DR   TubercuList; Rv2634c; -.
DR   eggNOG; COG3391; Bacteria.
DR   OMA; WTSRCSR; -.
DR   Proteomes; UP000001584; Chromosome.
DR   InterPro; IPR000084; PE-PGRS_N.
DR   Pfam; PF00934; PE; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..778
FT                   /note="Uncharacterized PE-PGRS family protein PE_PGRS46"
FT                   /id="PRO_0000216171"
FT   DOMAIN          1..92
FT                   /note="PE"
FT                   /evidence="ECO:0000255"
FT   REGION          125..163
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          372..510
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          718..778
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        374..407
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   778 AA;  63131 MW;  DAB20FE58E4999E7 CRC64;
     MSFVIAVPEA LTMAASDLAN IGSTINAANA AAALPTTGVV AAAADEVSAA VAALFGSYAQ
     SYQAFGAQLS AFHAQFVQSL TNGARSYVVA EATSAAPLQD LLGVVNAPAQ ALLGRPLIGN
     GANGADGTGA PGGPGGLLLG NGGNGGSGAP GQPGGAGGDA GLIGNGGTGG KGGDGLVGSG
     AAGGVGGRGG WLLGNGGTGG AGGAAGATLV GGTGGVGGAT GLIGSGGFGG AGGAAAGVGT
     TGGVGGSGGV GGVFGNGGFG GAGGLGAAGG VGGAASYFGT GGGGGVGGDG APGGDGGAGP
     LLIGNGGVGG LGGAGAAGGN GGAGGMLLGD GGAGGQGGPA VAGVLGGMPG AGGNGGNANW
     FGSGGAGGQG GTGLAGTNGV NPGSIANPNT GANGTDNSGN GNQTGGNGGP GPAGGVGEAG
     GVGGQGGLGE SLDGNDGTGG KGGAGGTAGT DGGAGGAGGA GGIGETDGSA GGVATGGEGG
     DGATGGVDGG VGGAGGKGGQ GHNTGVGDAF GGDGGIGGDG NGALGAAGGN GGTGGAGGNG
     GRGGMLIGNG GAGGAGGTGG TGGGGAAGFA GGVGGAGGEG LTDGAGTAEG GTGGLGGLGG
     VGGTGGMGGS GGVGGNGGAA GSLIGLGGGG GAGGVGGTGG IGGIGGAGGN GGAGGAGTTT
     GGGATIGGGG GTGGVGGAGG TGGTGGAGGT TGGSGGAGGL IGWAGAAGGT GAGGTGGQGG
     LGGQGGNGGN GGTGATGGQG GDFALGGNGG AGGAGGSPGG SSGIQGNMGP PGTQGADG