ID   PG54_MYCTU              Reviewed;        1901 AA.
AC   O53553; L0TFV3;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 1.
DT   25-MAY-2022, entry version 97.
DE   RecName: Full=Uncharacterized PE-PGRS family protein PE_PGRS54;
GN   Name=PE_PGRS54; OrderedLocusNames=Rv3508; ORFNames=MTV023.15;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA   Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA   Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA   Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA   Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT   "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT   mass spectrometry.";
RL   Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
CC   -!- SIMILARITY: Belongs to the mycobacterial PE family. PGRS subfamily.
CC       {ECO:0000305}.
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DR   EMBL; AL123456; CCP46330.1; -; Genomic_DNA.
DR   PIR; F70806; F70806.
DR   RefSeq; WP_010886172.1; NC_000962.3.
DR   RefSeq; YP_177979.1; NC_000962.3.
DR   AlphaFoldDB; O53553; -.
DR   STRING; 83332.Rv3508; -.
DR   PaxDb; O53553; -.
DR   GeneID; 888270; -.
DR   KEGG; mtu:Rv3508; -.
DR   PATRIC; fig|83332.12.peg.3915; -.
DR   TubercuList; Rv3508; -.
DR   eggNOG; COG0657; Bacteria.
DR   OMA; NINNICH; -.
DR   Proteomes; UP000001584; Chromosome.
DR   InterPro; IPR000084; PE-PGRS_N.
DR   Pfam; PF00934; PE; 1.
PE   1: Evidence at protein level;
KW   Reference proteome; Repeat.
FT   CHAIN           1..1901
FT                   /note="Uncharacterized PE-PGRS family protein PE_PGRS54"
FT                   /id="PRO_0000023578"
FT   DOMAIN          1..93
FT                   /note="PE"
FT                   /evidence="ECO:0000255"
FT   REGION          146..175
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          249..289
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          577..626
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          915..934
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1116..1135
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1254..1288
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1311..1355
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1415..1440
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1461..1495
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1519..1560
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1620..1645
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1666..1700
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1724..1761
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1809..1901
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1901 AA;  147625 MW;  C7B1923D5D0146CD CRC64;
     MSFVLIAPEF VTAAAGDLTN LGSSISAANA SAASATTQVL AAGADEVSAR IAALFGGFGL
     EYQAISAQVA AYHQRFVQAL STGAGAYASA EAAAAEQIVL GVINAPTQAL LGRPLIGDGA
     NATTPGGAGG AGGLLFGNGG AGAAGAPGQA GGPGGPAGLW GNGGPGGAGG SGGGTGGAGG
     AGGWLFGVGG AGGVGGAGGG TGGAGGPGGL IWGGGGAGGV GGAGGGTGGA GGRAELLFGA
     GGAGGAGTDG GPGATGGTGG HGGVGGDGGW LAPGGAGGAG GQGGAGGAGS DGGALGGTGG
     TGGTGGAGGA GGRGALLLGA GGQGGLGGAG GQGGTGGAGG DGVLGGVGGT GGKGGVGGVA
     GLGGAGGAAG QLFSAGGAAG AVGVGGTGGQ GGAGGAGAAG ADAPASTGLT GGTGFAGGAG
     GVGGQGGNAI AGGINGSGGA GGTGGQGGAG GMGGSGADNA SGIGADGGAG GTGGNAGAGG
     AGGAAGTGGT GGVVGAAGKA GIGGTGGQGG AGGAGSAGTD ATATGATGGT GFSGGAGGAG
     GAGGNTGVGG TNGSGGQGGT GGAGGAGGAG GVGADNPTGI GGTGGTGGKG GAGGAGGQGG
     SSGAGGTNGS GGAGGTGGQG GAGGAGGAGA DNPTGIGGAG GTGGTGGAAG AGGAGGAIGT
     GGTGGAVGSV GNAGIGGTGG TGGVGGAGGA GAAAAAGSSA TGGAGFAGGA GGEGGAGGNS
     GVGGTNGSGG AGGAGGKGGT GGAGGSGADN PTGAGFAGGA GGTGGAAGAG GAGGATGTGG
     TGGVVGATGS AGIGGAGGRG GDGGDGASGL GLGLSGFDGG QGGQGGAGGS AGAGGINGAG
     GAGGNGGDGG DGATGAAGLG DNGGVGGDGG AGGAAGNGGN AGVGLTAKAG DGGAAGNGGN
     GGAGGAGGAG DNNFNGGQGG AGGQGGQGGL GGASTTSINA NGGAGGNGGT GGKGGAGGAG
     TLGVGGSGGT GGDGGDAGSG GGGGFGGAAG KAGGGGNGGR GGDGGDGASG LGLGLSGFDG
     GQGGQGGAGG SAGAGGINGA GGAGGNGGDG GDGATGAAGL GDNGGVGGDG GAGGAAGNGG
     NAGVGLTAKA GDGGAAGNGG NGGAGGAGGA GDNNFNGGQG GAGGQGGQGG LGGASTTSIN
     ANGGAGGNGG TGGKGGAGGA GTLGVGGSGG TGGDGGDAGS GGGGGFGGAA GKAGGGGNGG
     VGGDGGEGAS GLGLGLSGFD GGQGGQGGAG GSAGAGGING AGGAGGTGGA GGDGAPATLI
     GGPDGGDGGQ GGIGGDGGNA GFGAGVPGDG GDGGNAGFGA GVPGDGGIGG TGGAGGAGGA
     GADGDPSIDG GQGGAGGHGG QGGKGGLNST GLASAASGDG GNGGAGGAGG NGGDGDGFIG
     GSGGTGGTGG DAGVGGLANT GGTAGNAGIG GAGGRGGDGG AGDSGALSQD GNGFAGGQGG
     QGGVGGNAGA GGINGAGGTG GTGGAGGDGQ NGTTGVASEG GAGGQGGDGG QGGIGGAGGN
     AGFGAGVPGD GGIGGTGGAG GAGGAGADGD PSIDGGQGGA GGHGGQGGKG GLNSTGLASA
     ASGDGGNGGA GGAGGNGGDG DGFIGGSGGT GGTGGDAGVG GLANTGGTAG NAGIGGAGGR
     GGDGGAGDSG ALSQDGNGFA GGQGGQGGVG GNAGAGGING AGGTGGTGGA GGDGQNGTTG
     VASEGGAGGQ GGDGGQGGIG GAGGNAGFGA GVPGDGGIGG TGGAGGAGGA GADGDPSIDG
     GQGGAGGHGG QGGKGGLNST GLASAASGDG GNGGAGGAGG NGGAGGLGGG GGTGGTNGNG
     GLGGGGGNGG AGGAGGTPTG SGTEGTGGDG GDAGAGGNGG SATGVGNGGN GGDGGNGGDG
     GNGAPGGFGG GAGAGGLGGS GAGGGTDGDD GNGGSPGTDG S