ID   PG60_MYCTU              Reviewed;         104 AA.
AC   Q6MWV1; V5QRY0;
DT   02-NOV-2016, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=PE-PGRS family protein PE_PGRS60 {ECO:0000305};
GN   Name=PE_PGRS60 {ECO:0000312|EMBL:CCP46475.1};
GN   OrderedLocusNames=Rv3652 {ECO:0000312|EMBL:CCP46475.1};
GN   ORFNames=LH57_19900 {ECO:0000312|EMBL:AIR16440.1};
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27294 / TMC 102 / H37Rv;
RA   Hazbon M.H., Riojas M.A., Damon A.M., Alalade R.O., Cantwell B.J.,
RA   Monaco A., King S., Sohrabi A.;
RT   "Phylogenetic analysis of Mycobacterial species using whole genome
RT   sequences.";
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   FUNCTION.
RC   STRAIN=H37Rv;
RX   PubMed=26158346; DOI=10.1002/bab.1411;
RA   Meena L.S., Meena J.;
RT   "Cloning and characterization of a novel PE_PGRS60 protein (Rv3652) of
RT   Mycobacterium tuberculosis H37 Rv exhibit fibronectin-binding property.";
RL   Biotechnol. Appl. Biochem. 63:525-531(2016).
CC   -!- FUNCTION: Binds fibronectin. May contribute to pathogenicity.
CC       {ECO:0000269|PubMed:26158346}.
CC   -!- SIMILARITY: Belongs to the mycobacterial PE family. PGRS subfamily.
CC       {ECO:0000305}.
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DR   EMBL; CP009480; AIR16440.1; -; Genomic_DNA.
DR   EMBL; AL123456; CCP46475.1; -; Genomic_DNA.
DR   RefSeq; WP_003901689.1; NC_000962.3.
DR   RefSeq; YP_178001.1; NC_000962.3.
DR   AlphaFoldDB; Q6MWV1; -.
DR   SMR; Q6MWV1; -.
DR   STRING; 83332.Rv3652; -.
DR   PaxDb; Q6MWV1; -.
DR   GeneID; 886260; -.
DR   KEGG; mtu:Rv3652; -.
DR   PATRIC; fig|83332.293.peg.4073; -.
DR   TubercuList; Rv3652; -.
DR   HOGENOM; CLU_000167_16_11_11; -.
DR   Proteomes; UP000001584; Chromosome.
DR   InterPro; IPR000084; PE-PGRS_N.
DR   Pfam; PF00934; PE; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..104
FT                   /note="PE-PGRS family protein PE_PGRS60"
FT                   /id="PRO_0000438130"
FT   DOMAIN          1..60
FT                   /note="PE"
FT                   /evidence="ECO:0000255"
FT   REGION          64..104
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   104 AA;  10636 MW;  54F22A9F7FA30ECA CRC64;
     MSYVIAAPEA LVAAATDLAT LGSTIGAANA AAAGSTTALL TAGADEVSAA IAAYSECTAR
     PIRHSVRGRR RSMSGSCRPW PQVGAPMRPP RPPASRRCRA RSIC