ID   PGA11_CANAL             Reviewed;         124 AA.
AC   Q5ACN3; A0A1D8PU77;
DT   11-DEC-2013, integrated into UniProtKB/Swiss-Prot.
DT   26-APR-2005, sequence version 1.
DT   25-MAY-2022, entry version 62.
DE   RecName: Full=Predicted GPI-anchored protein 11;
DE   Flags: Precursor;
GN   Name=PGA11; OrderedLocusNames=CAALFM_CR10330WA; ORFNames=CaO19.7609;
OS   Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=237561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA   Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA   Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA   Scherer S.;
RT   "The diploid genome sequence of Candida albicans.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA   van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA   Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA   Chibana H., Nantel A., Magee P.T.;
RT   "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT   on the eight chromosomes.";
RL   Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA   Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT   "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT   specific measurements and provides a simple model for repeat and indel
RT   structure.";
RL   Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
RN   [4]
RP   PREDICTION OF GPI-ANCHOR.
RX   PubMed=12845604; DOI=10.1002/yea.1007;
RA   De Groot P.W., Hellingwerf K.J., Klis F.M.;
RT   "Genome-wide identification of fungal GPI proteins.";
RL   Yeast 20:781-796(2003).
RN   [5]
RP   INDUCTION.
RX   PubMed=23208712; DOI=10.1128/aac.02040-12;
RA   Silva L.V., Sanguinetti M., Vandeputte P., Torelli R., Rochat B.,
RA   Sanglard D.;
RT   "Milbemycins: more than efflux inhibitors for fungal pathogens.";
RL   Antimicrob. Agents Chemother. 57:873-886(2013).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor, GPI-
CC       anchor {ECO:0000305}.
CC   -!- INDUCTION: Up-regulated upon milbemycins A3 oxim derivative (A3Ox)
CC       treatment. {ECO:0000269|PubMed:23208712}.
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DR   EMBL; CP017630; AOW31683.1; -; Genomic_DNA.
DR   RefSeq; XP_719370.1; XM_714277.1.
DR   AlphaFoldDB; Q5ACN3; -.
DR   STRING; 237561.Q5ACN3; -.
DR   GeneID; 3638939; -.
DR   KEGG; cal:CAALFM_CR10330WA; -.
DR   CGD; CAL0000189289; PGA11.
DR   VEuPathDB; FungiDB:CR_10330W_A; -.
DR   HOGENOM; CLU_2145546_0_0_1; -.
DR   OrthoDB; 1810630at2759; -.
DR   Proteomes; UP000000559; Chromosome R.
DR   GO; GO:0031225; C:anchored component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
PE   1: Evidence at protein level;
KW   Cell membrane; Glycoprotein; GPI-anchor; Lipoprotein; Membrane;
KW   Reference proteome; Signal.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000255"
FT   CHAIN           19..107
FT                   /note="Predicted GPI-anchored protein 11"
FT                   /id="PRO_0000424652"
FT   PROPEP          108..124
FT                   /note="Removed in mature form"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000424653"
FT   REGION          38..59
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        41..59
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   LIPID           107
FT                   /note="GPI-anchor amidated serine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   124 AA;  11796 MW;  027F99F6EFC87206 CRC64;
     MKFQFVTALA LASTMAVAAP INDQQEVLGA VAATRSKREG GSTGAELQDN NQPTAGLFGD
     GNSFGNQGLG GFLAATVDSL TKTIASPIKG ILAPGGGSGG NGGSGGSGAA GGVGNLFSGI
     LGGL