PGA43_CANAL
ID PGA43_CANAL Reviewed; 236 AA.
AC Q5A1A9; A0A1D8PMI7;
DT 22-JAN-2014, integrated into UniProtKB/Swiss-Prot.
DT 26-APR-2005, sequence version 1.
DT 25-MAY-2022, entry version 56.
DE RecName: Full=Predicted GPI-anchored protein 43;
DE Flags: Precursor;
GN Name=PGA43; OrderedLocusNames=CAALFM_C406260WA;
GN ORFNames=CaO19.10428, CaO19.2910;
OS Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=237561;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA Scherer S.;
RT "The diploid genome sequence of Candida albicans.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA Chibana H., Nantel A., Magee P.T.;
RT "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT on the eight chromosomes.";
RL Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT specific measurements and provides a simple model for repeat and indel
RT structure.";
RL Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
RN [4]
RP PREDICTION OF GPI-ANCHOR.
RX PubMed=12845604; DOI=10.1002/yea.1007;
RA De Groot P.W., Hellingwerf K.J., Klis F.M.;
RT "Genome-wide identification of fungal GPI proteins.";
RL Yeast 20:781-796(2003).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor, GPI-
CC anchor {ECO:0000305}.
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DR EMBL; CP017626; AOW29352.1; -; Genomic_DNA.
DR RefSeq; XP_715565.1; XM_710472.1.
DR AlphaFoldDB; Q5A1A9; -.
DR GeneID; 3642804; -.
DR KEGG; cal:CAALFM_C406260WA; -.
DR CGD; CAL0000197415; PGA43.
DR VEuPathDB; FungiDB:C4_06260W_A; -.
DR HOGENOM; CLU_101463_0_0_1; -.
DR InParanoid; Q5A1A9; -.
DR OMA; CALQSID; -.
DR OrthoDB; 1496012at2759; -.
DR PRO; PR:Q5A1A9; -.
DR Proteomes; UP000000559; Chromosome 4.
DR GO; GO:0031225; C:anchored component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
PE 1: Evidence at protein level;
KW Cell membrane; Glycoprotein; GPI-anchor; Lipoprotein; Membrane;
KW Reference proteome; Signal.
FT SIGNAL 1..24
FT /evidence="ECO:0000255"
FT CHAIN 25..208
FT /note="Predicted GPI-anchored protein 43"
FT /id="PRO_0000424945"
FT PROPEP 209..236
FT /note="Removed in mature form"
FT /evidence="ECO:0000255"
FT /id="PRO_0000424946"
FT LIPID 208
FT /note="GPI-anchor amidated glycine"
FT /evidence="ECO:0000255"
FT CARBOHYD 192
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 195
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 198
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 236 AA; 26292 MW; 523D609E5F143354 CRC64;
MHQRNHHSIL LTLLLYLQSI VALARIIDPE FGTYSNPNPR KYPQCQANDL VKLSSCCNEL
LHKLDQCKSD DLACECCALQ SIDRDCYHLC PGNPSTNFLT VLLQDCAQLS EINACALPFK
KTDDLLVDKK KGTPNSKSAV QALEADEKYD ASLKSKVHNK VDEIKSHVKQ DQFLKKKIKL
LIDKDETFAI QNHSNNSNNT ISAKSESGSV CLTSSYLNSP IIILCAILTG TLFAMY