ID   PGA53_CANAL             Reviewed;         139 AA.
AC   Q5AMJ5; A0A1D8PLE1; Q5AN01;
DT   09-JUL-2014, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2017, sequence version 2.
DT   25-MAY-2022, entry version 59.
DE   RecName: Full=GPI-anchored protein 53;
DE   Flags: Precursor;
GN   Name=PGA53; OrderedLocusNames=CAALFM_C401360WA;
GN   ORFNames=CaO19.12120, CaO19.4651;
OS   Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=237561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA   Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA   Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA   Scherer S.;
RT   "The diploid genome sequence of Candida albicans.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA   van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA   Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA   Chibana H., Nantel A., Magee P.T.;
RT   "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT   on the eight chromosomes.";
RL   Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA   Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT   "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT   specific measurements and provides a simple model for repeat and indel
RT   structure.";
RL   Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
RN   [4]
RP   PREDICTION OF GPI-ANCHOR.
RX   PubMed=12845604; DOI=10.1002/yea.1007;
RA   De Groot P.W., Hellingwerf K.J., Klis F.M.;
RT   "Genome-wide identification of fungal GPI proteins.";
RL   Yeast 20:781-796(2003).
RN   [5]
RP   IDENTIFICATION BY MASS SPECTROMETRY, AND SUBCELLULAR LOCATION.
RX   PubMed=19824013; DOI=10.1002/pmic.200800988;
RA   Cabezon V., Llama-Palacios A., Nombela C., Monteoliva L., Gil C.;
RT   "Analysis of Candida albicans plasma membrane proteome.";
RL   Proteomics 9:4770-4786(2009).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:19824013};
CC       Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:19824013}.
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DR   EMBL; CP017626; AOW28918.1; -; Genomic_DNA.
DR   RefSeq; XP_722722.2; XM_717629.2.
DR   AlphaFoldDB; Q5AMJ5; -.
DR   GeneID; 3635599; -.
DR   KEGG; cal:CAALFM_C401360WA; -.
DR   CGD; CAL0000200268; PGA53.
DR   VEuPathDB; FungiDB:C4_01360W_A; -.
DR   eggNOG; ENOG502RQFB; Eukaryota.
DR   HOGENOM; CLU_1844796_0_0_1; -.
DR   InParanoid; Q5AMJ5; -.
DR   OrthoDB; 1647738at2759; -.
DR   PRO; PR:Q5AMJ5; -.
DR   Proteomes; UP000000559; Chromosome 4.
DR   GO; GO:0046658; C:anchored component of plasma membrane; IDA:CGD.
PE   1: Evidence at protein level;
KW   Cell membrane; Glycoprotein; GPI-anchor; Lipoprotein; Membrane;
KW   Reference proteome; Signal.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000255"
FT   CHAIN           18..116
FT                   /note="GPI-anchored protein 53"
FT                   /id="PRO_0000429954"
FT   PROPEP          117..139
FT                   /note="Removed in mature form"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000429955"
FT   REGION          57..115
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   LIPID           116
FT                   /note="GPI-anchor amidated glycine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        93
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   139 AA;  14358 MW;  9E3424C53ED8F3F5 CRC64;
     MKFQLLTLVS IATTTLAINL EQVRLINDDE LMVQDAQFDY PAIVNLKDQD AEIAKKTITS
     SSSTTTTTTA KKDKKTTSTT SASSTTTTST KSNSTSPSSS SSKKHKSETA SITKTGGADS
     VAAAAAVGGP ILAALALLL