PGFRL_BOVIN
ID PGFRL_BOVIN Reviewed; 375 AA.
AC Q5BIP2;
DT 02-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT 12-APR-2005, sequence version 1.
DT 25-MAY-2022, entry version 79.
DE RecName: Full=Platelet-derived growth factor receptor-like protein;
DE Short=PDGFR-like protein;
DE Flags: Precursor;
GN Name=PDGFRL;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=16305752; DOI=10.1186/1471-2164-6-166;
RA Harhay G.P., Sonstegard T.S., Keele J.W., Heaton M.P., Clawson M.L.,
RA Snelling W.M., Wiedmann R.T., Van Tassell C.P., Smith T.P.L.;
RT "Characterization of 954 bovine full-CDS cDNA sequences.";
RL BMC Genomics 6:166-166(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Uterus;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Forms a complex composed of PDGFRL, TNK2 and GRB2.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
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DR EMBL; BT021182; AAX31364.1; -; mRNA.
DR EMBL; BC113220; AAI13221.1; -; mRNA.
DR RefSeq; NP_001030378.1; NM_001035301.1.
DR AlphaFoldDB; Q5BIP2; -.
DR SMR; Q5BIP2; -.
DR STRING; 9913.ENSBTAP00000002553; -.
DR PaxDb; Q5BIP2; -.
DR PRIDE; Q5BIP2; -.
DR GeneID; 515017; -.
DR KEGG; bta:515017; -.
DR CTD; 5157; -.
DR eggNOG; KOG0200; Eukaryota.
DR InParanoid; Q5BIP2; -.
DR OrthoDB; 825016at2759; -.
DR Proteomes; UP000009136; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR Gene3D; 2.60.40.10; -; 3.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR042495; PDGFRL.
DR PANTHER; PTHR15360:SF1; PTHR15360:SF1; 1.
DR SMART; SM00409; IG; 2.
DR SMART; SM00408; IGc2; 1.
DR SUPFAM; SSF48726; SSF48726; 3.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 2: Evidence at transcript level;
KW Disulfide bond; Glycoprotein; Immunoglobulin domain; Reference proteome;
KW Repeat; Secreted; Signal.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT CHAIN 22..375
FT /note="Platelet-derived growth factor receptor-like
FT protein"
FT /id="PRO_0000233089"
FT DOMAIN 62..159
FT /note="Ig-like C2-type 1"
FT DOMAIN 272..373
FT /note="Ig-like C2-type 2"
FT REGION 20..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 20..60
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 132
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 219
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT DISULFID 96..143
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00114"
FT DISULFID 293..357
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00114"
SQ SEQUENCE 375 AA; 41820 MW; DFAED45215899820 CRC64;
MKIWLLLGLL LMHEALEDVT GQHPPKNKRP KEPGENRIKP TNKKVKPKIP KIKDRDSADP
TPKTQSIMTQ MMDKGRFQKP AATLSLVAGQ TLELRCKGNK IGWSYPAYLD TFKDTRLSVK
QHERYGQLTL VNSTAADTGE FSCWGQLCTG YVCRRDEAKT GSTYIFFTEK GELFVPSPSH
FDVVYLNPDR QAVVPCRVTV LSAKVTLHRE FPAKEIPANG TDIVYDLKRG FVYLQPHVGH
QGVVYCKAEA GGKSQISVKY QLLYAEVPRG PPSTTILASS NKVKGGDDVS VLCTVLGEPD
VEVEFRWTYP GQKDERPVTI QDSWRLIHRG LGHTTRISQS VLSIEDFETI DAGYYICTAQ
NLQGQTTVAT TVESS
