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PGFRL_MACFA
ID   PGFRL_MACFA             Reviewed;         375 AA.
AC   Q2PFX1;
DT   02-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   07-FEB-2006, sequence version 1.
DT   03-AUG-2022, entry version 54.
DE   RecName: Full=Platelet-derived growth factor receptor-like protein;
DE            Short=PDGFR-like protein;
DE   Flags: Precursor;
GN   Name=PDGFRL; ORFNames=QflA-15761;
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Frontal cortex;
RA   Kobayashi M., Tanuma R., Hirata M., Osada N., Kusuda J., Sugano S.,
RA   Hashimoto K.;
RT   "Analysis of gene expression in cynomolgus monkey tissues by macaque cDNA
RT   oligo-chips.";
RL   Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Forms a complex composed of PDGFRL, TNK2 and GRB2.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
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DR   EMBL; AB220466; BAE72999.1; -; mRNA.
DR   RefSeq; NP_001271862.1; NM_001284933.1.
DR   AlphaFoldDB; Q2PFX1; -.
DR   STRING; 9541.XP_005562731.1; -.
DR   GeneID; 102145218; -.
DR   CTD; 5157; -.
DR   eggNOG; KOG0200; Eukaryota.
DR   OrthoDB; 825016at2759; -.
DR   Proteomes; UP000233100; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.60.40.10; -; 3.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR003598; Ig_sub2.
DR   InterPro; IPR042495; PDGFRL.
DR   PANTHER; PTHR15360:SF1; PTHR15360:SF1; 1.
DR   SMART; SM00409; IG; 2.
DR   SMART; SM00408; IGc2; 2.
DR   SUPFAM; SSF48726; SSF48726; 3.
DR   PROSITE; PS50835; IG_LIKE; 2.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Glycoprotein; Immunoglobulin domain; Reference proteome;
KW   Repeat; Secreted; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..375
FT                   /note="Platelet-derived growth factor receptor-like
FT                   protein"
FT                   /id="PRO_0000233091"
FT   DOMAIN          62..159
FT                   /note="Ig-like C2-type 1"
FT   DOMAIN          272..375
FT                   /note="Ig-like C2-type 2"
FT   REGION          22..64
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        22..60
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        132
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        219
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        96..143
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00114"
FT   DISULFID        293..357
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00114"
SQ   SEQUENCE   375 AA;  41834 MW;  99C6C88E1B815F0F CRC64;
     MKVWLLLGLL LVHEALEDVT GQHLPKNKRP KEPGENRIKP TNKKVKPKIP KIKDRDSADS
     TPKTQSIMMQ VLDKGRFQKP AATLSLLAGQ SVELRCKGSR IGWSYPAYLD TFKDSRISVK
     QNERYGQLTL VNSTSADTGE FSCWGQLCSG YICRKDETKT GSTYIFFTEK GELFVPSPSY
     FDVVYLNPDR QAVVPCRVTV LSAKVTLHRE FPAKEIPANG TDIVYDMKRG FVYLQPHSEH
     QGVVYCRAEA GGRSQISVKY QLLYVAVPSG PPSTTILASS NKVKSGDDVS VLCTVLGEPD
     VEVEFTWIFP GQKDERPVTI QDTWRLIHRG LGHTTRLSQS VITVEDFETI DAGYYICTAQ
     NLQGQTTVAT TVEFS
 
 
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