ID   PGKH_TOBAC              Reviewed;         481 AA.
AC   Q42961;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=Phosphoglycerate kinase, chloroplastic;
DE            EC=2.7.2.3;
DE   Flags: Precursor;
OS   Nicotiana tabacum (Common tobacco).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC   Nicotiana.
OX   NCBI_TaxID=4097;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Samsun; TISSUE=Leaf;
RA   Rao S.K., Bringloe D.H., Dyer T.A., Raines C.A., Bradbeer J.W.;
RT   "Nucleotide sequences of cDNAs encoding the chloroplastic and cytosolic
RT   phosphoglycerate kinases from tobacco.";
RL   (er) Plant Gene Register PGR95-090(1995).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl
CC         phosphate + ADP; Xref=Rhea:RHEA:14801, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:57604, ChEBI:CHEBI:58272, ChEBI:CHEBI:456216; EC=2.7.2.3;
CC   -!- PATHWAY: Carbohydrate biosynthesis; Calvin cycle.
CC   -!- SUBUNIT: Monomer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast.
CC   -!- SIMILARITY: Belongs to the phosphoglycerate kinase family.
CC       {ECO:0000305}.
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DR   EMBL; Z48977; CAA88841.1; -; mRNA.
DR   PIR; T03660; T03660.
DR   AlphaFoldDB; Q42961; -.
DR   SMR; Q42961; -.
DR   STRING; 4097.Q42961; -.
DR   PRIDE; Q42961; -.
DR   ProMEX; Q42961; -.
DR   UniPathway; UPA00116; -.
DR   Proteomes; UP000084051; Unplaced.
DR   GO; GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0043531; F:ADP binding; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IBA:GO_Central.
DR   GO; GO:0004618; F:phosphoglycerate kinase activity; IBA:GO_Central.
DR   GO; GO:0006094; P:gluconeogenesis; IBA:GO_Central.
DR   GO; GO:0006096; P:glycolytic process; IBA:GO_Central.
DR   GO; GO:0019253; P:reductive pentose-phosphate cycle; IEA:UniProtKB-UniPathway.
DR   CDD; cd00318; Phosphoglycerate_kinase; 1.
DR   Gene3D; 3.40.50.1260; -; 3.
DR   HAMAP; MF_00145; Phosphoglyc_kinase; 1.
DR   InterPro; IPR001576; Phosphoglycerate_kinase.
DR   InterPro; IPR015911; Phosphoglycerate_kinase_CS.
DR   InterPro; IPR015824; Phosphoglycerate_kinase_N.
DR   InterPro; IPR036043; Phosphoglycerate_kinase_sf.
DR   PANTHER; PTHR11406; PTHR11406; 1.
DR   Pfam; PF00162; PGK; 1.
DR   PIRSF; PIRSF000724; Pgk; 1.
DR   PRINTS; PR00477; PHGLYCKINASE.
DR   SUPFAM; SSF53748; SSF53748; 1.
DR   PROSITE; PS00111; PGLYCERATE_KINASE; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding; Calvin cycle; Chloroplast; Kinase; Nucleotide-binding;
KW   Plastid; Reference proteome; Transferase; Transit peptide.
FT   TRANSIT         1..75
FT                   /note="Chloroplast"
FT                   /evidence="ECO:0000255"
FT   CHAIN           76..481
FT                   /note="Phosphoglycerate kinase, chloroplastic"
FT                   /id="PRO_0000023892"
FT   BINDING         99..101
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
FT   BINDING         115
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
FT   BINDING         138..141
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
FT   BINDING         196
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
FT   BINDING         229
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
FT   BINDING         280
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000250"
FT   BINDING         371
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000250"
FT   BINDING         402
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000250"
FT   BINDING         431..434
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   481 AA;  50177 MW;  7AA497C747D0716D CRC64;
     MASATASHTL CGIPATSSST TNKAIAPSSA RFLAKTPLRR LGFAGAAADS LFTNHVATKL
     RSLKSSSKPI RGVASMAKKS VGDLTAAELK GKKVFVRADL NVPLDDNQNI TDDTRIRAAV
     PTIKHLMANG AKVILSSHLG RPKGVTPKYS LAPLVPRLSE LLGIQVVKVE DCIGPEVEKL
     VASLPEGGVL LLENVRFYKE EEKNEPEFAK KLASLADLYV NDAFGTAHRA HASTEGVTKF
     LKPSVAGFLL QKELDYLVGA VSNPKRPFAA IVGGSKVSSK IGVIESLLEK CDILLLGGGM
     IFTFYKAQGL SVGSSLVEED KLELATSLLE KAKAKGVSLL LPSDVVIADK FAPDANSKIV
     PASAIPDGWM GLDIGPDSVK TFNDALDTTK TVIWNGPMGV FEFDKFAVGT EAIAKKLADL
     SGKGVTTIIG GGDSVAAVEK VGVASVMSHI STGGGASLEL LEGKVLPGVI ALDEADAPVA
     V