PGML4_ARATH
ID PGML4_ARATH Reviewed; 230 AA.
AC Q9SCS3;
DT 29-OCT-2014, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 118.
DE RecName: Full=Phosphoglycerate mutase-like protein 4 {ECO:0000305};
GN OrderedLocusNames=At3g50520 {ECO:0000312|Araport:AT3G50520};
GN ORFNames=T20E23.120 {ECO:0000312|EMBL:CAB62481.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
CC -!- FUNCTION: May play a role in carbohydrates metabolism.
CC {ECO:0000250|UniProtKB:Q9MAA2}.
CC -!- SIMILARITY: Belongs to the phosphoglycerate mutase family.
CC {ECO:0000305}.
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DR EMBL; AL133363; CAB62481.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE78675.1; -; Genomic_DNA.
DR EMBL; AY035101; AAK59606.1; -; mRNA.
DR EMBL; AY063062; AAL34236.1; -; mRNA.
DR PIR; T46083; T46083.
DR RefSeq; NP_190621.1; NM_114912.5.
DR AlphaFoldDB; Q9SCS3; -.
DR SMR; Q9SCS3; -.
DR BioGRID; 9534; 1.
DR STRING; 3702.AT3G50520.1; -.
DR PaxDb; Q9SCS3; -.
DR PRIDE; Q9SCS3; -.
DR ProteomicsDB; 236141; -.
DR EnsemblPlants; AT3G50520.1; AT3G50520.1; AT3G50520.
DR GeneID; 824216; -.
DR Gramene; AT3G50520.1; AT3G50520.1; AT3G50520.
DR KEGG; ath:AT3G50520; -.
DR Araport; AT3G50520; -.
DR TAIR; locus:2098690; AT3G50520.
DR eggNOG; KOG0235; Eukaryota.
DR HOGENOM; CLU_033323_14_0_1; -.
DR InParanoid; Q9SCS3; -.
DR OMA; TEWNVAR; -.
DR OrthoDB; 1112626at2759; -.
DR PhylomeDB; Q9SCS3; -.
DR BioCyc; ARA:AT3G50520-MON; -.
DR PRO; PR:Q9SCS3; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9SCS3; baseline and differential.
DR Genevisible; Q9SCS3; AT.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0016791; F:phosphatase activity; IBA:GO_Central.
DR CDD; cd07067; HP_PGM_like; 1.
DR Gene3D; 3.40.50.1240; -; 1.
DR InterPro; IPR013078; His_Pase_superF_clade-1.
DR InterPro; IPR029033; His_PPase_superfam.
DR InterPro; IPR001345; PG/BPGM_mutase_AS.
DR Pfam; PF00300; His_Phos_1; 1.
DR SMART; SM00855; PGAM; 1.
DR SUPFAM; SSF53254; SSF53254; 1.
DR PROSITE; PS00175; PG_MUTASE; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..230
FT /note="Phosphoglycerate mutase-like protein 4"
FT /id="PRO_0000430634"
FT ACT_SITE 21
FT /note="Tele-phosphohistidine intermediate"
FT /evidence="ECO:0000250|UniProtKB:P62707"
FT ACT_SITE 96
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000250|UniProtKB:P62707"
FT SITE 165
FT /note="Transition state stabilizer"
FT /evidence="ECO:0000250|UniProtKB:P62707"
SQ SEQUENCE 230 AA; 25979 MW; ACBFDE7EECA55DB0 CRC64;
MEESRFDSED VDYAEIVVVR HGETSWNAER KIQGHLDVEL NDAGRQQAQR VAERLSKEQK
ISHVYSSDLK RAFETAQIIA AKCGKLEVLT DRDLRERHLG DMQGLVYQEA SKIRPEAYKA
FSSNRTDVDI PGGGESLDKL YDRCTTALQR IGDKHKGERI VVVTHGGVIR SLYERARPSA
RKVEKILNTS VNVFRLFDGD KWTIQVWGDV SHLEETGFLQ SGFGGDRTSG
