ID   PGMR_ASPTN              Reviewed;         186 AA.
AC   Q0CJC9;
DT   03-AUG-2022, integrated into UniProtKB/Swiss-Prot.
DT   17-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 68.
DE   RecName: Full=Transcription factor pgmR {ECO:0000303|PubMed:35351612};
DE   AltName: Full=Pigmented naphthoquinones biosynthesis cluster protein R {ECO:0000303|PubMed:35351612};
GN   Name=pgmR {ECO:0000303|PubMed:28471414}; ORFNames=ATEG_06205;
OS   Aspergillus terreus (strain NIH 2624 / FGSC A1156).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=341663;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NIH 2624 / FGSC A1156;
RA   Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Henn M.,
RA   Ma L.-J., Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M.,
RA   Kleber M., Mauceli E.W., Brockman W., Rounsley S., Young S.K., LaButti K.,
RA   Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA   Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA   Alvarado L., Kodira C.D., Zeng Q., Oleary S., Yandava C., Denning D.W.,
RA   Nierman W.C., Milne T., Madden K.;
RT   "Annotation of the Aspergillus terreus NIH2624 genome.";
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   IDENTIFICATION, AND FUNCTION.
RC   STRAIN=MUCL38669;
RX   PubMed=28471414; DOI=10.3390/microorganisms5020022;
RA   Palonen E.K., Raina S., Brandt A., Meriluoto J., Keshavarz T., Soini J.T.;
RT   "Melanisation of Aspergillus terreus-is butyrolactone I involved in the
RT   regulation of both DOPA and DHN types of pigments in submerged culture?";
RL   Microorganisms 5:0-0(2017).
RN   [3]
RP   FUNCTION, AND INDUCTION.
RX   PubMed=35351612; DOI=10.1016/j.fgb.2022.103690;
RA   Tang S., Men P., Zhang W., Li H., Li Z., Huang X., Lu X.;
RT   "Identification of a polyketide biosynthesis gene cluster by
RT   transcriptional regulator activation in Aspergillus terreus.";
RL   Fungal Genet. Biol. 160:103690-103690(2022).
CC   -!- FUNCTION: Transcription factor that specifically regulates the
CC       expression of the pgm gene cluster that mediates the biosynthesis of
CC       cryptic naphthoquinones derived pigments responsible for the coloration
CC       of the fruiting bodies. {ECO:0000269|PubMed:28471414,
CC       ECO:0000269|PubMed:35351612}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00227}.
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DR   EMBL; CH476601; EAU33966.1; -; Genomic_DNA.
DR   RefSeq; XP_001215383.1; XM_001215383.1.
DR   EnsemblFungi; EAU33966; EAU33966; ATEG_06205.
DR   GeneID; 4321474; -.
DR   VEuPathDB; FungiDB:ATEG_06205; -.
DR   HOGENOM; CLU_1454103_0_0_1; -.
DR   OrthoDB; 1396569at2759; -.
DR   Proteomes; UP000007963; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd00067; GAL4; 1.
DR   Gene3D; 4.10.240.10; -; 1.
DR   InterPro; IPR001138; Zn2-C6_fun-type_DNA-bd.
DR   InterPro; IPR036864; Zn2-C6_fun-type_DNA-bd_sf.
DR   Pfam; PF00172; Zn_clus; 1.
DR   SMART; SM00066; GAL4; 1.
DR   SUPFAM; SSF57701; SSF57701; 1.
DR   PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation; Zinc.
FT   CHAIN           1..186
FT                   /note="Transcription factor pgmR"
FT                   /id="PRO_0000456005"
FT   DNA_BIND        19..46
FT                   /note="Zn(2)-C6 fungal-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00227"
SQ   SEQUENCE   186 AA;  19314 MW;  5FBBF3B88649C904 CRC64;
     MADSTPVRMP RAPKLRASCD ECGAAKLKCD RGHPSCGRCI SLGLKCVYGV SRKAGKPRRD
     AQSATRPPPT PGDSGPPLDY NSFGPTSPPS SVGDGATLAS GLLPGAADLS PLDWGPGSSS
     SYRAVVDLCS RYAKEPMRMD DTAMSSVWDG FLEPSLFATY GSPVQVARLA GGSVPFSAAP
     VRDLPI