PGM_ARATH
ID PGM_ARATH Reviewed; 271 AA.
AC Q8GY96;
DT 29-OCT-2014, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 113.
DE RecName: Full=Phosphoglycerate mutase-like protein {ECO:0000303|PubMed:15010616};
DE Short=AtPGM {ECO:0000303|PubMed:15010616};
GN Name=PGM {ECO:0000303|PubMed:15010616};
GN OrderedLocusNames=At2g17280 {ECO:0000312|Araport:AT2G17280}; ORFNames=F5J6;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000312|EMBL:BAC42426.1};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP TISSUE SPECIFICITY, AND INDUCTION.
RX PubMed=15010616; DOI=10.1023/b:plan.0000019062.80459.80;
RA Mazarei M., Lennon K.A., Puthoff D.P., Rodermel S.R., Baum T.J.;
RT "Expression of an Arabidopsis phosphoglycerate mutase homologue is
RT localized to apical meristems, regulated by hormones, and induced by
RT sedentary plant-parasitic nematodes.";
RL Plant Mol. Biol. 53:513-530(2003).
CC -!- FUNCTION: May play a role in carbohydrates metabolism.
CC {ECO:0000250|UniProtKB:Q9MAA2}.
CC -!- TISSUE SPECIFICITY: Expressed in the shoot apical meristem and
CC meristematic zone of the root tips. {ECO:0000269|PubMed:15010616}.
CC -!- INDUCTION: By auxin, sucrose, oryzalin and the nematodes Heterodera
CC schachtii and Meloidogyne incognita in roots. Down-regulated by
CC abscisic acid (ABA) and hydroxyurea. {ECO:0000269|PubMed:15010616}.
CC -!- SIMILARITY: Belongs to the phosphoglycerate mutase family.
CC {ECO:0000305}.
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DR EMBL; CP002685; AEC06607.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC06608.1; -; Genomic_DNA.
DR EMBL; AK117779; BAC42426.1; -; mRNA.
DR EMBL; BT006234; AAP12883.1; -; mRNA.
DR PIR; C84550; C84550.
DR RefSeq; NP_001077906.1; NM_001084437.2.
DR RefSeq; NP_179320.1; NM_127283.6.
DR AlphaFoldDB; Q8GY96; -.
DR SMR; Q8GY96; -.
DR STRING; 3702.AT2G17280.2; -.
DR iPTMnet; Q8GY96; -.
DR PaxDb; Q8GY96; -.
DR PRIDE; Q8GY96; -.
DR ProteomicsDB; 234902; -.
DR EnsemblPlants; AT2G17280.1; AT2G17280.1; AT2G17280.
DR EnsemblPlants; AT2G17280.2; AT2G17280.2; AT2G17280.
DR GeneID; 816234; -.
DR Gramene; AT2G17280.1; AT2G17280.1; AT2G17280.
DR Gramene; AT2G17280.2; AT2G17280.2; AT2G17280.
DR KEGG; ath:AT2G17280; -.
DR Araport; AT2G17280; -.
DR TAIR; locus:2827577; AT2G17280.
DR eggNOG; KOG4754; Eukaryota.
DR HOGENOM; CLU_039184_4_0_1; -.
DR InParanoid; Q8GY96; -.
DR OMA; GRWEDEF; -.
DR OrthoDB; 1063916at2759; -.
DR PhylomeDB; Q8GY96; -.
DR PRO; PR:Q8GY96; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q8GY96; baseline and differential.
DR Genevisible; Q8GY96; AT.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0016791; F:phosphatase activity; IBA:GO_Central.
DR CDD; cd07067; HP_PGM_like; 1.
DR Gene3D; 3.40.50.1240; -; 1.
DR InterPro; IPR013078; His_Pase_superF_clade-1.
DR InterPro; IPR029033; His_PPase_superfam.
DR Pfam; PF00300; His_Phos_1; 2.
DR SMART; SM00855; PGAM; 1.
DR SUPFAM; SSF53254; SSF53254; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..271
FT /note="Phosphoglycerate mutase-like protein"
FT /id="PRO_0000430631"
FT REGION 252..271
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 22
FT /note="Tele-phosphohistidine intermediate"
FT /evidence="ECO:0000250|UniProtKB:P62707"
FT ACT_SITE 134
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000250|UniProtKB:P62707"
FT SITE 205
FT /note="Transition state stabilizer"
FT /evidence="ECO:0000250|UniProtKB:P62707"
SQ SEQUENCE 271 AA; 29890 MW; 588088C486752F23 CRC64;
MDNEGIGLYP LHRCKTIHLV RHAQGIHNVA GEKDHSAYSS EDYFDAHLTP LGWQQVDNLR
NHVRAAQLLN KVELVIVSPM LRTIQTAVGA FGGEEDTNGA DATPLMVANA GSSDRPAISS
LNSPPFLAVE LCRETMGDHP CDRRRSVTEY KALFPAIDFS IIETDNDVLW KPSPRESLEE
VAARGVEFIK WIWTRKEKEI AIVSHSGFLH GLLSSFGKDC CDDLKKELSI HLSNCELRSM
VIVDRGNLGT DSAETTNYPG KVPEGLDNPS G
