ID   PGTC_SALTI              Reviewed;         397 AA.
AC   P0A234; P37591;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Phosphoglycerate transport regulatory protein PgtC;
DE   Flags: Precursor;
GN   Name=pgtC; OrderedLocusNames=STY2635, t0460;
OS   Salmonella typhi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90370;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CT18;
RX   PubMed=11677608; DOI=10.1038/35101607;
RA   Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA   Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA   Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA   Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA   Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA   Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA   Barrell B.G.;
RT   "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT   serovar Typhi CT18.";
RL   Nature 413:848-852(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700931 / Ty2;
RX   PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA   Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA   Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT   "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT   CT18.";
RL   J. Bacteriol. 185:2330-2337(2003).
CC   -!- FUNCTION: Required for pgtP expression, it may act jointly with the
CC       PgtA/PgtB signaling proteins. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AL513382; CAD07635.1; -; Genomic_DNA.
DR   EMBL; AE014613; AAO68172.1; -; Genomic_DNA.
DR   RefSeq; NP_456940.1; NC_003198.1.
DR   RefSeq; WP_000467983.1; NZ_WSUR01000045.1.
DR   AlphaFoldDB; P0A234; -.
DR   STRING; 220341.16503622; -.
DR   EnsemblBacteria; AAO68172; AAO68172; t0460.
DR   KEGG; stt:t0460; -.
DR   KEGG; sty:STY2635; -.
DR   PATRIC; fig|220341.7.peg.2668; -.
DR   eggNOG; COG1840; Bacteria.
DR   HOGENOM; CLU_040513_1_0_6; -.
DR   OMA; IMWNTRY; -.
DR   Proteomes; UP000000541; Chromosome.
DR   Proteomes; UP000002670; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Signal; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255"
FT   CHAIN           25..397
FT                   /note="Phosphoglycerate transport regulatory protein PgtC"
FT                   /id="PRO_0000022044"
FT   TRANSMEM        102..117
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   397 AA;  44016 MW;  507D1DEC3B1E05C3 CRC64;
     MFGSCQAYSR ELVMATTFSP SATAWIIQRW QTEPGSVMIR TLNRTSGSLE QLLDTANAEN
     VDLILTSSPM LLQHLQEHQK LALLDSAPAA SQKLVPRSIR STSVAVAVSG FGLLINRSAL
     AARHLPPPAD WQDMGLPSYQ GALLMSSPSR SDTNHLMVES LLQQKGWTAG WATLLAISGN
     LVTISSRSFG VADKIKSGLG VAGPVIDNYA NLLLNDPNLA FTYFPYSAVS PTYVAVLKNS
     RHADEARAFI HYLLSPKGQR ILADANTGKY PVAPLSADNP RAAQQQRLMA QPPLNYRLIL
     KRQQLVQRMF DTAISFRLAQ LKDAWRALHS AETRLKRPLP EIRALLTSVP VDAASSEDET
     WLAQFDNKSF AEQKMMEWQI WFLNNQRLAI HKLEELK