ID   PGTC_SALTY              Reviewed;         397 AA.
AC   P0A233; P37591;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 83.
DE   RecName: Full=Phosphoglycerate transport regulatory protein PgtC;
DE   Flags: Precursor;
GN   Name=pgtC; OrderedLocusNames=STM2398;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=LT2;
RX   PubMed=2842311; DOI=10.1128/jb.170.9.4299-4303.1988;
RA   Yang Y.L., Goldrick D., Hong J.-S.;
RT   "Identification of the products and nucleotide sequences of two regulatory
RT   genes involved in the exogenous induction of phosphoglycerate transport in
RT   Salmonella typhimurium.";
RL   J. Bacteriol. 170:4299-4303(1988).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
RN   [3]
RP   CHARACTERIZATION.
RC   STRAIN=LT2;
RX   PubMed=2842312; DOI=10.1128/jb.170.9.4304-4308.1988;
RA   Jiang S.Q., Yu G.Q., Li Z.G., Hong J.-S.;
RT   "Genetic evidence for modulation of the activator by two regulatory
RT   proteins involved in the exogenous induction of phosphoglycerate transport
RT   in Salmonella typhimurium.";
RL   J. Bacteriol. 170:4304-4308(1988).
CC   -!- FUNCTION: Required for PgtP expression, it may act jointly with the
CC       PgtA/PgtB signaling proteins.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA68214.1; Type=Frameshift; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; M21279; AAA68214.1; ALT_FRAME; Genomic_DNA.
DR   EMBL; AE006468; AAL21298.1; -; Genomic_DNA.
DR   RefSeq; NP_461339.1; NC_003197.2.
DR   RefSeq; WP_000467983.1; NC_003197.2.
DR   AlphaFoldDB; P0A233; -.
DR   STRING; 99287.STM2398; -.
DR   PaxDb; P0A233; -.
DR   EnsemblBacteria; AAL21298; AAL21298; STM2398.
DR   GeneID; 1253920; -.
DR   KEGG; stm:STM2398; -.
DR   PATRIC; fig|99287.12.peg.2536; -.
DR   HOGENOM; CLU_040513_1_0_6; -.
DR   OMA; IMWNTRY; -.
DR   PhylomeDB; P0A233; -.
DR   BioCyc; SENT99287:STM2398-MON; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
PE   1: Evidence at protein level;
KW   Cell membrane; Membrane; Reference proteome; Signal; Transmembrane;
KW   Transmembrane helix.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255"
FT   CHAIN           25..397
FT                   /note="Phosphoglycerate transport regulatory protein PgtC"
FT                   /id="PRO_0000022045"
FT   TRANSMEM        102..117
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        45
FT                   /note="T -> S (in Ref. 1; AAA68214)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   397 AA;  44016 MW;  507D1DEC3B1E05C3 CRC64;
     MFGSCQAYSR ELVMATTFSP SATAWIIQRW QTEPGSVMIR TLNRTSGSLE QLLDTANAEN
     VDLILTSSPM LLQHLQEHQK LALLDSAPAA SQKLVPRSIR STSVAVAVSG FGLLINRSAL
     AARHLPPPAD WQDMGLPSYQ GALLMSSPSR SDTNHLMVES LLQQKGWTAG WATLLAISGN
     LVTISSRSFG VADKIKSGLG VAGPVIDNYA NLLLNDPNLA FTYFPYSAVS PTYVAVLKNS
     RHADEARAFI HYLLSPKGQR ILADANTGKY PVAPLSADNP RAAQQQRLMA QPPLNYRLIL
     KRQQLVQRMF DTAISFRLAQ LKDAWRALHS AETRLKRPLP EIRALLTSVP VDAASSEDET
     WLAQFDNKSF AEQKMMEWQI WFLNNQRLAI HKLEELK