PH11A_MOUSE
ID PH11A_MOUSE Reviewed; 293 AA.
AC Q8BVM9;
DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=PHD finger protein 11A;
DE AltName: Full=PHD finger protein 11;
DE AltName: Full=PHD finger protein 11-like;
GN Name=Phf11a; Synonyms=Phf11, Phf11-4, Phf11l;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Thymus;
RA Flynn E.K., Symer D.E.;
RT "Conserved transcription-mediated gene fusion at the Setdb2-Phf11 locus.";
RL Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.;
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Thymus;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
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DR EMBL; EU155109; ABY55495.1; -; mRNA.
DR EMBL; AK077176; BAC36663.1; -; mRNA.
DR EMBL; CH466535; EDL36141.1; -; Genomic_DNA.
DR EMBL; BC116758; AAI16759.1; -; mRNA.
DR EMBL; BC116760; AAI16761.1; -; mRNA.
DR CCDS; CCDS27169.1; -.
DR RefSeq; NP_766191.1; NM_172603.3.
DR AlphaFoldDB; Q8BVM9; -.
DR SMR; Q8BVM9; -.
DR IntAct; Q8BVM9; 1.
DR STRING; 10090.ENSMUSP00000053146; -.
DR iPTMnet; Q8BVM9; -.
DR PhosphoSitePlus; Q8BVM9; -.
DR MaxQB; Q8BVM9; -.
DR PaxDb; Q8BVM9; -.
DR PRIDE; Q8BVM9; -.
DR ProteomicsDB; 289483; -.
DR DNASU; 219131; -.
DR Ensembl; ENSMUST00000062307; ENSMUSP00000053146; ENSMUSG00000044703.
DR GeneID; 219131; -.
DR KEGG; mmu:219131; -.
DR UCSC; uc007uee.2; mouse.
DR CTD; 219131; -.
DR MGI; MGI:1918441; Phf11a.
DR VEuPathDB; HostDB:ENSMUSG00000044703; -.
DR eggNOG; KOG1084; Eukaryota.
DR GeneTree; ENSGT00950000182865; -.
DR HOGENOM; CLU_076108_0_0_1; -.
DR InParanoid; Q8BVM9; -.
DR OMA; AHENCLX; -.
DR OrthoDB; 783078at2759; -.
DR PhylomeDB; Q8BVM9; -.
DR TreeFam; TF325426; -.
DR BioGRID-ORCS; 219131; 3 hits in 51 CRISPR screens.
DR ChiTaRS; Phf11a; mouse.
DR PRO; PR:Q8BVM9; -.
DR Proteomes; UP000000589; Chromosome 14.
DR RNAct; Q8BVM9; protein.
DR Bgee; ENSMUSG00000044703; Expressed in morula and 34 other tissues.
DR Genevisible; Q8BVM9; MM.
DR GO; GO:0031965; C:nuclear membrane; ISO:MGI.
DR GO; GO:0005654; C:nucleoplasm; ISO:MGI.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0050776; P:regulation of immune response; IMP:MGI.
DR Gene3D; 3.30.40.10; -; 1.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PROSITE; PS51805; EPHD; 1.
PE 2: Evidence at transcript level;
KW Metal-binding; Nucleus; Reference proteome; Zinc; Zinc-finger.
FT CHAIN 1..293
FT /note="PHD finger protein 11A"
FT /id="PRO_0000385017"
FT ZN_FING 25..61
FT /note="C2HC pre-PHD-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01146"
FT ZN_FING 91..143
FT /note="PHD-type; degenerate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01146"
FT REGION 262..293
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 293 AA; 32673 MW; 29648C96340DCFD1 CRC64;
MAQEKPGCSN PVPNGDCPII EKMEKRTCAL CPEGHEWSQI YFSPSANIVA HENCLLYSSG
LVECEAPDLP NTVRNFDVKS VKKEIGRGRR LKCSFCKNKG ATMGYDLQSC TKNYHLSCAM
EDHAILQVDE DHGTYKLFCQ KHAPEGQEPT QRDAAVKAPF LKKCQEAGLL NVLLEYILEK
MDLIHGRLLN ETASESDYEG IETLLFGCGL FGDTLRKFQE VINSKACEWE ERQRLMKQQL
EALADLQQNL CSFQENGDLD CSSSTSGSLL PPEDHQVRCQ ESPEVQAGSG DSL
