ID   PHAA1_NOSS1             Reviewed;         161 AA.
AC   P80555;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   03-AUG-2022, entry version 117.
DE   RecName: Full=Allophycocyanin subunit alpha 1;
GN   Name=apcA1; OrderedLocusNames=alr0021;
OS   Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576).
OC   Bacteria; Cyanobacteria; Nostocales; Nostocaceae; Nostoc.
OX   NCBI_TaxID=103690;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Cai Y.A., Schwarts S.H., Glazer A.N.;
RT   "Transposon insertion in genes coding for the biosynthesis of structural
RT   components of the Anabaena sp. phycobilisome.";
RL   Photosyn. Res. 53:109-120(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 7120 / SAG 25.82 / UTEX 2576;
RX   PubMed=11759840; DOI=10.1093/dnares/8.5.205;
RA   Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A.,
RA   Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M.,
RA   Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M.,
RA   Takazawa M., Yamada M., Yasuda M., Tabata S.;
RT   "Complete genomic sequence of the filamentous nitrogen-fixing
RT   cyanobacterium Anabaena sp. strain PCC 7120.";
RL   DNA Res. 8:205-213(2001).
RN   [3]
RP   PROTEIN SEQUENCE OF 2-60.
RX   PubMed=8665889; DOI=10.1111/j.1432-1033.1996.01010.x;
RA   Ducret A., Sidler W., Wehrli E., Frank G., Zuber H.;
RT   "Isolation, characterization and electron microscopy analysis of a
RT   hemidiscoidal phycobilisome type from the cyanobacterium Anabaena sp. PCC
RT   7120.";
RL   Eur. J. Biochem. 236:1010-1024(1996).
RN   [4]
RP   CHROMOPHORE ATTACHMENT AT CYS-81.
RC   STRAIN=PCC 7120 / SAG 25.82 / UTEX 2576;
RX   PubMed=17726096; DOI=10.1073/pnas.0706209104;
RA   Zhao K.H., Su P., Tu J.M., Wang X., Liu H., Ploscher M., Eichacker L.,
RA   Yang B., Zhou M., Scheer H.;
RT   "Phycobilin:cystein-84 biliprotein lyase, a near-universal lyase for
RT   cysteine-84-binding sites in cyanobacterial phycobiliproteins.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:14300-14305(2007).
CC   -!- FUNCTION: Light-harvesting photosynthetic bile pigment-protein from the
CC       phycobiliprotein complex. Allophycocyanin has a maximum absorption at
CC       approximately 650 to 653 nanometers.
CC   -!- SUBUNIT: Heterohexamer of two alpha chains, one alpha-B chain and three
CC       beta chains.
CC   -!- SUBCELLULAR LOCATION: Cellular thylakoid membrane; Peripheral membrane
CC       protein; Cytoplasmic side. Note=Forms the core of the phycobilisome.
CC   -!- PTM: Contains one covalently linked phycocyanobilin chromophore
CC       (Probable). The chromophore is added by phycocyanobilin lyase CpcS 1.
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the phycobiliprotein family. {ECO:0000305}.
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DR   EMBL; U96137; AAC97590.1; -; Genomic_DNA.
DR   EMBL; BA000019; BAB77545.1; -; Genomic_DNA.
DR   PIR; AE1809; AE1809.
DR   RefSeq; WP_010994198.1; NZ_RSCN01000016.1.
DR   PDB; 7EYD; EM; 3.90 A; A8/A9/C8/C9/E8/E9/G9/H8/I9/J8/K9/L8/N9/O8/P9/Q8/R9/S8/T9/V8/X8/X9/Z8/Z9/b9/c8/d9/e8/f9/g8=1-161.
DR   PDBsum; 7EYD; -.
DR   AlphaFoldDB; P80555; -.
DR   SMR; P80555; -.
DR   STRING; 103690.17134999; -.
DR   EnsemblBacteria; BAB77545; BAB77545; BAB77545.
DR   GeneID; 58725378; -.
DR   KEGG; ana:alr0021; -.
DR   eggNOG; ENOG502Z7RG; Bacteria.
DR   OMA; GGQLFQK; -.
DR   OrthoDB; 1461468at2; -.
DR   Proteomes; UP000002483; Chromosome.
DR   GO; GO:0030089; C:phycobilisome; IEA:UniProtKB-KW.
DR   GO; GO:0031676; C:plasma membrane-derived thylakoid membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015979; P:photosynthesis; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.490.20; -; 1.
DR   InterPro; IPR009050; Globin-like_sf.
DR   InterPro; IPR012128; Phycobilisome_asu/bsu.
DR   InterPro; IPR038719; Phycobilisome_asu/bsu_sf.
DR   Pfam; PF00502; Phycobilisome; 1.
DR   PIRSF; PIRSF000081; Phycocyanin; 1.
DR   SUPFAM; SSF46458; SSF46458; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Antenna complex; Bile pigment; Chromophore;
KW   Direct protein sequencing; Electron transport; Membrane; Methylation;
KW   Photosynthesis; Phycobilisome; Reference proteome; Thylakoid; Transport.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000269|PubMed:8665889"
FT   CHAIN           2..161
FT                   /note="Allophycocyanin subunit alpha 1"
FT                   /id="PRO_0000199070"
FT   BINDING         81
FT                   /ligand="(2R,3E)-phycocyanobilin"
FT                   /ligand_id="ChEBI:CHEBI:85275"
FT                   /note="covalent, via 1 link"
FT                   /evidence="ECO:0000305"
FT   MOD_RES         71
FT                   /note="N4-methylasparagine"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   161 AA;  17346 MW;  221567965EFF2740 CRC64;
     MSIVTKSIVN ADAEARYLSP GELDRIKSFV AGGQQRLRIA QALTDNRERL VKQAGDQLFQ
     KRPDVVSPGG NAYGQEMTAT CLRDLDYYLR LVTYGIVAGD VTPIEEIGVI GVREMYKSLG
     TPIEAVGEGV RALKNAASTL LSAEDAAEAG SYFDYVVGAL Q