ID   PHAA_SYNP2              Reviewed;         161 AA.
AC   B1XQM2; O68969;
DT   11-JAN-2011, integrated into UniProtKB/Swiss-Prot.
DT   20-MAY-2008, sequence version 1.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=Allophycocyanin alpha subunit;
GN   Name=apcA; OrderedLocusNames=SYNPCC7002_A1930;
OS   Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (Agmenellum
OS   quadruplicatum).
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae; Synechococcus;
OC   unclassified Synechococcus.
OX   NCBI_TaxID=32049;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 27264 / PCC 7002 / PR-6;
RA   Zhou J., Stirewalt V.L., Bryant D.A.;
RT   "Cloning and characterization of the apcABC operon of Synechococcus sp. PCC
RT   7002.";
RL   Submitted (APR-1998) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27264 / PCC 7002 / PR-6;
RA   Li T., Zhao J., Zhao C., Liu Z., Zhao F., Marquardt J., Nomura C.T.,
RA   Persson S., Detter J.C., Richardson P.M., Lanz C., Schuster S.C., Wang J.,
RA   Li S., Huang X., Cai T., Yu Z., Luo J., Zhao J., Bryant D.A.;
RT   "Complete sequence of Synechococcus sp. PCC 7002.";
RL   Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   MASS SPECTROMETRY, AND CHROMOPHORE ATTACHMENT.
RC   STRAIN=ATCC 27264 / PCC 7002 / PR-6;
RX   PubMed=18199754; DOI=10.1074/jbc.m708164200;
RA   Shen G., Schluchter W.M., Bryant D.A.;
RT   "Biogenesis of phycobiliproteins: I. cpcS-I and cpcU mutants of the
RT   cyanobacterium Synechococcus sp. PCC 7002 define a heterodimeric
RT   phyococyanobilin lyase specific for beta-phycocyanin and allophycocyanin
RT   subunits.";
RL   J. Biol. Chem. 283:7503-7512(2008).
CC   -!- FUNCTION: Light-harvesting photosynthetic bile pigment-protein from the
CC       phycobiliprotein complex. Allophycocyanin has a maximum absorption at
CC       approximately 650 nanometers (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Heterodimer of an alpha and a beta chain. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cellular thylakoid membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}; Cytoplasmic side
CC       {ECO:0000250}. Note=Forms the core of the phycobilisome. {ECO:0000250}.
CC   -!- PTM: Contains one covalently linked phycocyanobilin chromophore. The
CC       chromophore on position 81 is added by the phycocyanobilin lyase CpcUS.
CC   -!- MASS SPECTROMETRY: Mass=17741; Method=Electrospray; Note=The measured
CC       mass is that of the protein without the N-terminal Met plus one
CC       covalently linked phycocyanobilin chromophore.;
CC       Evidence={ECO:0000269|PubMed:18199754};
CC   -!- SIMILARITY: Belongs to the phycobiliprotein family. {ECO:0000305}.
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DR   EMBL; AF059339; AAC14719.1; -; Genomic_DNA.
DR   EMBL; CP000951; ACA99917.1; -; Genomic_DNA.
DR   RefSeq; WP_012307540.1; NC_010475.1.
DR   PDB; 7EXT; EM; 3.50 A; A7/C7/E7/G3/H7/I3/J7/K3/L7/N3/O7/P3/Q7/R3/S7/T3/V7/X3/X7/Z3/Z7/b3/d3/f3/i3/k3/o3/q3/s3/u3=1-161.
DR   PDBsum; 7EXT; -.
DR   AlphaFoldDB; B1XQM2; -.
DR   SMR; B1XQM2; -.
DR   STRING; 32049.SYNPCC7002_A1930; -.
DR   EnsemblBacteria; ACA99917; ACA99917; SYNPCC7002_A1930.
DR   KEGG; syp:SYNPCC7002_A1930; -.
DR   eggNOG; ENOG502Z7RG; Bacteria.
DR   HOGENOM; CLU_104219_2_0_3; -.
DR   OMA; GGQLFQK; -.
DR   Proteomes; UP000001688; Chromosome.
DR   GO; GO:0030089; C:phycobilisome; IEA:UniProtKB-KW.
DR   GO; GO:0031676; C:plasma membrane-derived thylakoid membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015979; P:photosynthesis; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.490.20; -; 1.
DR   InterPro; IPR009050; Globin-like_sf.
DR   InterPro; IPR012128; Phycobilisome_asu/bsu.
DR   InterPro; IPR038719; Phycobilisome_asu/bsu_sf.
DR   Pfam; PF00502; Phycobilisome; 1.
DR   PIRSF; PIRSF000081; Phycocyanin; 1.
DR   SUPFAM; SSF46458; SSF46458; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Antenna complex; Bile pigment; Chromophore;
KW   Electron transport; Membrane; Photosynthesis; Phycobilisome;
KW   Reference proteome; Thylakoid; Transport.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000305"
FT   CHAIN           2..161
FT                   /note="Allophycocyanin alpha subunit"
FT                   /id="PRO_0000403175"
FT   BINDING         81
FT                   /ligand="(2R,3E)-phycocyanobilin"
FT                   /ligand_id="ChEBI:CHEBI:85275"
FT                   /note="covalent, via 1 link"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        42
FT                   /note="T -> N (in Ref. 1; AAC14719)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   161 AA;  17286 MW;  BD50562663923FE0 CRC64;
     MSIVTKSIVN ADAEARYLSP GELDRIKAFV TSGESRLRIA ETLTGSRERI IKSAGDALFQ
     KRPDVVSPGG NAYGEEMTAT CLRDMDYYLR LITYGVVAGD VTPIEEIGLV GVREMYKSLG
     TPVDAVAQAV REMKAVATGM MSGDDAAEAG AYFDYVIGAM E