ID   PHAA_SYNY3              Reviewed;         161 AA.
AC   Q01951;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   03-AUG-2022, entry version 134.
DE   RecName: Full=Allophycocyanin alpha chain;
GN   Name=apcA; OrderedLocusNames=slr2067;
OS   Synechocystis sp. (strain PCC 6803 / Kazusa).
OC   Bacteria; Cyanobacteria; Synechococcales; Merismopediaceae; Synechocystis;
OC   unclassified Synechocystis.
OX   NCBI_TaxID=1111708;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1429645; DOI=10.1016/s0021-9258(18)50038-7;
RA   Su X., Goodman P., Bogorad L.;
RT   "Excitation energy transfer from phycocyanin to chlorophyll in an apcA-
RT   defective mutant of Synechocystis sp. PCC 6803.";
RL   J. Biol. Chem. 267:22944-22950(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 6803 / Kazusa;
RX   PubMed=8905231; DOI=10.1093/dnares/3.3.109;
RA   Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y.,
RA   Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T.,
RA   Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.,
RA   Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence analysis of the genome of the unicellular cyanobacterium
RT   Synechocystis sp. strain PCC6803. II. Sequence determination of the entire
RT   genome and assignment of potential protein-coding regions.";
RL   DNA Res. 3:109-136(1996).
RN   [3]
RP   PROTEIN SEQUENCE OF 2-21.
RX   PubMed=9298645; DOI=10.1002/elps.1150180806;
RA   Sazuka T., Ohara O.;
RT   "Towards a proteome project of cyanobacterium Synechocystis sp. strain
RT   PCC6803: linking 130 protein spots with their respective genes.";
RL   Electrophoresis 18:1252-1258(1997).
CC   -!- FUNCTION: Light-harvesting photosynthetic bile pigment-protein from the
CC       phycobiliprotein complex. Allophycocyanin has a maximum absorption at
CC       approximately 650 nanometers.
CC   -!- SUBUNIT: Heterodimer of an alpha and a beta chain. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cellular thylakoid membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}; Cytoplasmic side
CC       {ECO:0000250}. Note=Forms the core of the phycobilisome. {ECO:0000250}.
CC   -!- PTM: Contains one covalently linked phycocyanobilin chromophore.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the phycobiliprotein family. {ECO:0000305}.
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DR   EMBL; M77135; AAA27276.1; -; Genomic_DNA.
DR   EMBL; BA000022; BAA17874.1; -; Genomic_DNA.
DR   PIR; A44462; A44462.
DR   AlphaFoldDB; Q01951; -.
DR   SMR; Q01951; -.
DR   IntAct; Q01951; 3.
DR   STRING; 1148.1652957; -.
DR   PaxDb; Q01951; -.
DR   PRIDE; Q01951; -.
DR   EnsemblBacteria; BAA17874; BAA17874; BAA17874.
DR   KEGG; syn:slr2067; -.
DR   eggNOG; ENOG502Z7RG; Bacteria.
DR   InParanoid; Q01951; -.
DR   OMA; GGQLFQK; -.
DR   PhylomeDB; Q01951; -.
DR   Proteomes; UP000001425; Chromosome.
DR   GO; GO:0030089; C:phycobilisome; IDA:UniProtKB.
DR   GO; GO:0031676; C:plasma membrane-derived thylakoid membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015979; P:photosynthesis; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.490.20; -; 1.
DR   InterPro; IPR009050; Globin-like_sf.
DR   InterPro; IPR012128; Phycobilisome_asu/bsu.
DR   InterPro; IPR038719; Phycobilisome_asu/bsu_sf.
DR   Pfam; PF00502; Phycobilisome; 1.
DR   PIRSF; PIRSF000081; Phycocyanin; 1.
DR   SUPFAM; SSF46458; SSF46458; 1.
PE   1: Evidence at protein level;
KW   Antenna complex; Bile pigment; Chromophore; Direct protein sequencing;
KW   Electron transport; Membrane; Methylation; Photosynthesis; Phycobilisome;
KW   Reference proteome; Thylakoid; Transport.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..161
FT                   /note="Allophycocyanin alpha chain"
FT                   /id="PRO_0000199078"
FT   BINDING         81
FT                   /ligand="(2R,3E)-phycocyanobilin"
FT                   /ligand_id="ChEBI:CHEBI:85275"
FT                   /note="covalent, via 1 link"
FT                   /evidence="ECO:0000250"
FT   MOD_RES         71
FT                   /note="N4-methylasparagine"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   161 AA;  17412 MW;  428A932F556F3392 CRC64;
     MSIVTKSIVN ADAEARYLSP GELDRIKAFV TGGAARLRIA ETLTGSRETI VKQAGDRLFQ
     KRPDIVSPGG NAYGEEMTAT CLRDMDYYLR LVTYGVVSGD VTPIEEIGLV GVREMYRSLG
     TPIEAVAQSV REMKEVASGL MSSDDAAEAS AYFDFVIGKM S