PHAX_CHICK
ID PHAX_CHICK Reviewed; 399 AA.
AC Q5ZLY0;
DT 13-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 23-NOV-2004, sequence version 1.
DT 03-AUG-2022, entry version 68.
DE RecName: Full=Phosphorylated adapter RNA export protein;
DE AltName: Full=RNA U small nuclear RNA export adapter protein;
GN Name=PHAX; Synonyms=RNUXA; ORFNames=RCJMB04_4h18;
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=CB; TISSUE=Bursa of Fabricius;
RX PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA Hayashizaki Y., Buerstedde J.-M.;
RT "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT function analysis.";
RL Genome Biol. 6:R6.1-R6.9(2005).
CC -!- FUNCTION: Probably involved in protein and RNA export from the nucleus.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the PHAX family. {ECO:0000305}.
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DR EMBL; AJ719604; CAG31263.1; -; mRNA.
DR RefSeq; NP_001006575.1; NM_001006575.2.
DR AlphaFoldDB; Q5ZLY0; -.
DR SMR; Q5ZLY0; -.
DR STRING; 9031.ENSGALP00000023634; -.
DR PaxDb; Q5ZLY0; -.
DR GeneID; 427124; -.
DR KEGG; gga:427124; -.
DR CTD; 51808; -.
DR VEuPathDB; HostDB:geneid_427124; -.
DR eggNOG; KOG3948; Eukaryota.
DR InParanoid; Q5ZLY0; -.
DR OrthoDB; 1223195at2759; -.
DR PhylomeDB; Q5ZLY0; -.
DR PRO; PR:Q5ZLY0; -.
DR Proteomes; UP000000539; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0006408; P:snRNA export from nucleus; IBA:GO_Central.
DR Gene3D; 1.10.10.1440; -; 1.
DR InterPro; IPR039047; PHAX.
DR InterPro; IPR019385; PHAX_RNA-binding_domain.
DR InterPro; IPR038092; PHAX_RNA-binding_sf.
DR PANTHER; PTHR13135; PTHR13135; 1.
DR Pfam; PF10258; RNA_GG_bind; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Nucleus; Protein transport; Reference proteome; RNA-binding;
KW Transport.
FT CHAIN 1..399
FT /note="Phosphorylated adapter RNA export protein"
FT /id="PRO_0000239778"
FT REGION 1..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 31..69
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 399 AA; 45393 MW; 9549E6FF8D466FE6 CRC64;
MALEVRRMEG DVEDGELSDS DSDMPGAGSP RERQQKSNDG SNAGRPFQSS ISSGVPDVPY
RTTKSVDSSD ESFSESDDDS SLWKRKRQKC FNFPPAKCEP FPLNQSHAKQ TALGGKKVNN
IWGMVLQEQN QDAVATELGI LGMDGSIDRS RQSETYNYLL AKKLMKEAQQ KEAETLDKEL
DEYMHDDKKT LPAEEENGQG FLKRKRSVKD RLGERQEMKY KGRYEITEED SEEKVADEIA
YRLCEPKKDL IARVVKIIGK RKAIELLMET AEVEQNGGLF IVNGTRRRTP GGVYLNLLKN
TPSIKEEQIK EIFYLENQKE YENKKAAKKR RIQVLGKKMK KAIKGLNLQE YDDASRETFA
SDTNEALASL DDLQDGHHEA KMEHEDIIEI DNAHDLEIF