ID   PHCA2_MICDP             Reviewed;         162 AA.
AC   P08040;
DT   01-AUG-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1988, sequence version 1.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=C-phycocyanin-2 alpha subunit;
GN   Name=cpcA2;
OS   Microchaete diplosiphon (Fremyella diplosiphon).
OC   Bacteria; Cyanobacteria; Nostocales; Rivulariaceae; Microchaete.
OX   NCBI_TaxID=1197;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3126486; DOI=10.1093/nar/16.4.1626;
RA   Capuano V., Mazel D., Tandeau de Marsac N., Houmard J.;
RT   "Complete nucleotide sequence of the red-light specific set of phycocyanin
RT   genes from the cyanobacterium Calothrix PCC 7601.";
RL   Nucleic Acids Res. 16:1626-1626(1988).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3127591; DOI=10.1016/0022-2836(88)90617-1;
RA   Conley P.B., Lemaux P.G., Grossman A.;
RT   "Molecular characterization and evolution of sequences encoding light-
RT   harvesting components in the chromatically adapting cyanobacterium
RT   Fremyella diplosiphon.";
RL   J. Mol. Biol. 199:447-465(1988).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-19.
RX   PubMed=3931221; DOI=10.1126/science.3931221;
RA   Conley P.B., Lemaux P.G., Grossman A.R.;
RT   "Cyanobacterial light-harvesting complex subunits encoded in two red light-
RT   induced transcripts.";
RL   Science 230:550-553(1985).
CC   -!- FUNCTION: Light-harvesting photosynthetic bile pigment-protein from the
CC       phycobiliprotein complex (phycobilisome, PBS). Phycocyanin is the major
CC       phycobiliprotein in the PBS rod.
CC   -!- SUBUNIT: Heterodimer of an alpha and a beta subunit, which further
CC       assembles into trimers and the trimers into hexamers.
CC       {ECO:0000250|UniProtKB:P13530}.
CC   -!- SUBCELLULAR LOCATION: Cellular thylakoid membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}; Cytoplasmic side
CC       {ECO:0000250}. Note=Part of the phycobilisome rod. {ECO:0000250}.
CC   -!- INDUCTION: Phycocyanin-2 is expressed in red but not in green light
CC       (inducible phycocyanin).
CC   -!- PTM: Contains one covalently linked bilin chromophore.
CC       {ECO:0000250|UniProtKB:P13530}.
CC   -!- SIMILARITY: Belongs to the phycobiliprotein family. {ECO:0000305}.
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DR   EMBL; X06451; CAA29751.1; -; Genomic_DNA.
DR   EMBL; X07012; CAA30062.1; -; Genomic_DNA.
DR   EMBL; M36276; AAA23290.1; -; Genomic_DNA.
DR   EMBL; M11929; AAA24889.1; -; Genomic_DNA.
DR   AlphaFoldDB; P08040; -.
DR   SMR; P08040; -.
DR   GO; GO:0030089; C:phycobilisome; IEA:UniProtKB-KW.
DR   GO; GO:0031676; C:plasma membrane-derived thylakoid membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015979; P:photosynthesis; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.490.20; -; 1.
DR   InterPro; IPR009050; Globin-like_sf.
DR   InterPro; IPR012128; Phycobilisome_asu/bsu.
DR   InterPro; IPR038719; Phycobilisome_asu/bsu_sf.
DR   InterPro; IPR006246; Phycocyanin_a.
DR   Pfam; PF00502; Phycobilisome; 1.
DR   PIRSF; PIRSF000081; Phycocyanin; 1.
DR   SUPFAM; SSF46458; SSF46458; 1.
DR   TIGRFAMs; TIGR01338; phycocy_alpha; 1.
PE   2: Evidence at transcript level;
KW   Antenna complex; Bile pigment; Chromophore; Electron transport; Membrane;
KW   Photosynthesis; Phycobilisome; Thylakoid; Transport.
FT   CHAIN           1..162
FT                   /note="C-phycocyanin-2 alpha subunit"
FT                   /id="PRO_0000199114"
FT   BINDING         84
FT                   /ligand="(2R,3E)-phycocyanobilin"
FT                   /ligand_id="ChEBI:CHEBI:85275"
FT                   /note="covalent, via 1 link"
FT                   /evidence="ECO:0000250|UniProtKB:P13530"
FT   CONFLICT        8
FT                   /note="A -> G (in Ref. 2; CAA30062)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        55..56
FT                   /note="AV -> TA (in Ref. 2; CAA30062)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        150
FT                   /note="A -> V (in Ref. 2; CAA30062)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   162 AA;  17466 MW;  AF93FAFC5DB46135 CRC64;
     MKTPLTEAVA TADSQGRFLS STELQVAFGR FRQASASLDA AKALSSKANS LAQGAVNAVY
     QKFPYTTQMQ GKNFASDQRG KDKCARDIGY YIRIVTYCLV AGGTGPLDDY LIGGLAEINR
     TFDLSPSWYV EALKYIKANH GLSGDPAVEA NSYIDYAINA LS