ID   PHCA3_MICDP             Reviewed;         162 AA.
AC   P14876;
DT   01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1990, sequence version 1.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=C-phycocyanin-3 alpha subunit;
GN   Name=cpcA3;
OS   Microchaete diplosiphon (Fremyella diplosiphon).
OC   Bacteria; Cyanobacteria; Nostocales; Rivulariaceae; Microchaete.
OX   NCBI_TaxID=1197;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Mazel D., Houmard J., Tandeau de Marsac N.;
RT   "A multigene family in Calothrix sp. PCC 7601 encodes phycocyanin, the
RT   major component of the cyanobacterial light harvesting antenna.";
RL   Mol. Gen. Genet. 211:296-304(1988).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2506452; DOI=10.1038/341245a0;
RA   Mazel D., Marliere P.;
RT   "Adaptive eradication of methionine and cysteine from cyanobacterial light-
RT   harvesting proteins.";
RL   Nature 341:245-248(1989).
CC   -!- FUNCTION: Light-harvesting photosynthetic bile pigment-protein from the
CC       phycobiliprotein complex (phycobilisome, PBS). Phycocyanin is the major
CC       phycobiliprotein in the PBS rod.
CC   -!- SUBUNIT: Heterodimer of an alpha and a beta subunit, which further
CC       assembles into trimers and the trimers into hexamers.
CC       {ECO:0000250|UniProtKB:P13530}.
CC   -!- SUBCELLULAR LOCATION: Cellular thylakoid membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}; Cytoplasmic side
CC       {ECO:0000250}. Note=Part of the phycobilisome rod. {ECO:0000250}.
CC   -!- INDUCTION: Phycocyanin-3 is expressed in red light under conditions of
CC       sulfur deprivation.
CC   -!- PTM: Contains one covalently linked bilin chromophore. {ECO:0000250,
CC       ECO:0000250|UniProtKB:P13530}.
CC   -!- SIMILARITY: Belongs to the phycobiliprotein family. {ECO:0000305}.
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DR   EMBL; X06083; CAA29460.1; -; Genomic_DNA.
DR   AlphaFoldDB; P14876; -.
DR   SMR; P14876; -.
DR   GO; GO:0030089; C:phycobilisome; IEA:UniProtKB-KW.
DR   GO; GO:0031676; C:plasma membrane-derived thylakoid membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015979; P:photosynthesis; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.490.20; -; 1.
DR   InterPro; IPR009050; Globin-like_sf.
DR   InterPro; IPR012128; Phycobilisome_asu/bsu.
DR   InterPro; IPR038719; Phycobilisome_asu/bsu_sf.
DR   InterPro; IPR006246; Phycocyanin_a.
DR   Pfam; PF00502; Phycobilisome; 1.
DR   PIRSF; PIRSF000081; Phycocyanin; 1.
DR   SUPFAM; SSF46458; SSF46458; 1.
DR   TIGRFAMs; TIGR01338; phycocy_alpha; 1.
PE   2: Evidence at transcript level;
KW   Antenna complex; Bile pigment; Chromophore; Electron transport; Membrane;
KW   Photosynthesis; Phycobilisome; Thylakoid; Transport.
FT   CHAIN           1..162
FT                   /note="C-phycocyanin-3 alpha subunit"
FT                   /id="PRO_0000199115"
FT   BINDING         84
FT                   /ligand="(2R,3E)-phycocyanobilin"
FT                   /ligand_id="ChEBI:CHEBI:85275"
FT                   /note="covalent, via 1 link"
FT                   /evidence="ECO:0000250|UniProtKB:P13530"
SQ   SEQUENCE   162 AA;  17393 MW;  0679FC970554EDD6 CRC64;
     MTKTPLTEAV VSADSQGRFL STELQVAFGR FRQAGSSLEA AKALSKKASS LAEAAANAVY
     QKFPYTTTTS GPNYASTQTG KDKCVRDIGY YLRIVTYGLV VGGTGPIDDY LIGGLAEINR
     TFELSPSWYI EALKYIKANH GLSGDPAVEA NSYIDYIINA LS