PHCA_CYAPA
ID PHCA_CYAPA Reviewed; 162 AA.
AC P05730;
DT 01-NOV-1988, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1996, sequence version 2.
DT 03-AUG-2022, entry version 97.
DE RecName: Full=C-phycocyanin alpha subunit;
GN Name=cpcA; Synonyms=pcyA;
OS Cyanophora paradoxa.
OG Plastid; Cyanelle.
OC Eukaryota; Glaucocystophyceae; Cyanophoraceae; Cyanophora.
OX NCBI_TaxID=2762;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UTEX LB 555 / Pringsheim;
RA Stirewalt V.L., Michalowski C.B., Loeffelhardt W., Bohnert H.J.,
RA Bryant D.A.;
RT "Nucleotide sequence of the cyanelle DNA from Cyanophora paradoxa.";
RL Plant Mol. Biol. Rep. 13:327-332(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UTEX LB 555 / Pringsheim;
RA Loeffelhardt W., Stirewalt V.L., Michalowski C.B., Annarella M.,
RA Farley J.Y., Schluchter W.M., Chung S., Newmann-Spallart C., Steiner J.M.,
RA Jakowitsch J., Bohnert H.J., Bryant D.A.;
RT "The complete sequence of the cyanelle genome of Cyanophora paradoxa: the
RT genetic complexity of a primitive plastid.";
RL (In) Schenk H.E.A., Herrmann R., Jeon K.W., Mueller N.E., Schwemmler W.
RL (eds.);
RL Eukaryotism and symbiosis, pp.40-48, Springer-Verlag, Heidelberg (1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-15.
RX PubMed=2998775; DOI=10.1002/j.1460-2075.1985.tb03870.x;
RA Lemaux P.G., Grossman A.R.;
RT "Major light-harvesting polypeptides encoded in polycistronic transcripts
RT in a eukaryotic alga.";
RL EMBO J. 4:1911-1919(1985).
CC -!- FUNCTION: Light-harvesting photosynthetic bile pigment-protein from the
CC phycobiliprotein complex (phycobilisome, PBS). Phycocyanin is the major
CC phycobiliprotein in the PBS rod.
CC -!- SUBUNIT: Heterodimer of an alpha and a beta subunit, which further
CC assembles into trimers and the trimers into hexamers. The basic
CC functional unit of phycobiliproteins is a ring-shaped hexamer formed
CC from two back-to-back trimers contacting via the alpha chain subunits.
CC The trimers are composed of alpha/beta subunit heterodimers arranged
CC around a three-fold axis of symmetry. The phycoerythrins also contain a
CC gamma subunit which is located in the center of the hexamer.
CC {ECO:0000250|UniProtKB:P00306}.
CC -!- SUBCELLULAR LOCATION: Plastid, cyanelle thylakoid membrane
CC {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Stromal side
CC {ECO:0000250}. Note=Part of the phycobilisome rod. {ECO:0000250}.
CC -!- PTM: Contains one covalently linked phycocyanobilin chromophore.
CC {ECO:0000250|UniProtKB:P00306}.
CC -!- SIMILARITY: Belongs to the phycobiliprotein family. {ECO:0000305}.
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DR EMBL; U30821; AAA81311.1; -; Genomic_DNA.
DR EMBL; X02790; CAA26557.1; -; Genomic_DNA.
DR PIR; T06968; T06968.
DR RefSeq; NP_043280.1; NC_001675.1.
DR AlphaFoldDB; P05730; -.
DR SMR; P05730; -.
DR GeneID; 801580; -.
DR GO; GO:0033115; C:cyanelle thylakoid membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0030089; C:phycobilisome; IEA:UniProtKB-KW.
DR GO; GO:0015979; P:photosynthesis; IEA:UniProtKB-KW.
DR Gene3D; 1.10.490.20; -; 1.
DR InterPro; IPR009050; Globin-like_sf.
DR InterPro; IPR012128; Phycobilisome_asu/bsu.
DR InterPro; IPR038719; Phycobilisome_asu/bsu_sf.
DR InterPro; IPR006246; Phycocyanin_a.
DR Pfam; PF00502; Phycobilisome; 1.
DR PIRSF; PIRSF000081; Phycocyanin; 1.
DR SUPFAM; SSF46458; SSF46458; 1.
DR TIGRFAMs; TIGR01338; phycocy_alpha; 1.
PE 3: Inferred from homology;
KW Antenna complex; Bile pigment; Chromophore; Cyanelle; Electron transport;
KW Membrane; Photosynthesis; Phycobilisome; Plastid; Thylakoid; Transport.
FT CHAIN 1..162
FT /note="C-phycocyanin alpha subunit"
FT /id="PRO_0000199119"
FT BINDING 84
FT /ligand="(2R,3E)-phycocyanobilin"
FT /ligand_id="ChEBI:CHEBI:85275"
FT /note="covalent, via 1 link"
FT /evidence="ECO:0000250|UniProtKB:P00306"
SQ SEQUENCE 162 AA; 17513 MW; 30BA91A389036AF4 CRC64;
MKTPITEAIA TADNQGRFLS NSELHASFGR FQRAASALEA ARSLTSNSQK LIDGAAAAVY
QKFPYTTQTF GPQYASTAEG KAKCTRDIGY YLRIVTYALV AGGTGPLDEY LVAGLEEMNR
AFDLSPSWYV EALKYIKANH GLSGQAATEA NGYFDYVINA LS