PHCA_SYNY1
ID PHCA_SYNY1 Reviewed; 163 AA.
AC P20776;
DT 01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 2.
DT 03-AUG-2022, entry version 80.
DE RecName: Full=C-phycocyanin alpha subunit;
GN Name=cpcA;
OS Synechocystis sp. (strain PCC 6701).
OC Bacteria; Cyanobacteria; Oscillatoriophycideae; Chroococcales;
OC Chroococcaceae; Geminocystis; unclassified Geminocystis.
OX NCBI_TaxID=1144;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2106506; DOI=10.1128/jb.172.3.1289-1296.1990;
RA Anderson L.K., Grossman A.R.;
RT "Genes for phycocyanin subunits in Synechocystis sp. strain PCC 6701 and
RT assembly mutant UV16.";
RL J. Bacteriol. 172:1289-1296(1990).
CC -!- FUNCTION: Light-harvesting photosynthetic bile pigment-protein from the
CC phycobiliprotein complex (phycobilisome, PBS). Phycocyanin is the major
CC phycobiliprotein in the PBS rod.
CC -!- SUBUNIT: Heterodimer of an alpha and a beta subunit, which further
CC assembles into trimers and the trimers into hexamers.
CC {ECO:0000250|UniProtKB:P13530}.
CC -!- SUBCELLULAR LOCATION: Cellular thylakoid membrane {ECO:0000250};
CC Peripheral membrane protein {ECO:0000250}; Cytoplasmic side
CC {ECO:0000250}. Note=Part of the phycobilisome rod. {ECO:0000250}.
CC -!- PTM: Contains one covalently linked phycocyanobilin chromophore.
CC {ECO:0000250|UniProtKB:P13530}.
CC -!- SIMILARITY: Belongs to the phycobiliprotein family. {ECO:0000305}.
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DR EMBL; M33820; AAA27282.1; -; Genomic_DNA.
DR PIR; B35126; B35126.
DR AlphaFoldDB; P20776; -.
DR SMR; P20776; -.
DR GO; GO:0030089; C:phycobilisome; IEA:UniProtKB-KW.
DR GO; GO:0031676; C:plasma membrane-derived thylakoid membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015979; P:photosynthesis; IEA:UniProtKB-KW.
DR Gene3D; 1.10.490.20; -; 1.
DR InterPro; IPR009050; Globin-like_sf.
DR InterPro; IPR012128; Phycobilisome_asu/bsu.
DR InterPro; IPR038719; Phycobilisome_asu/bsu_sf.
DR InterPro; IPR006246; Phycocyanin_a.
DR Pfam; PF00502; Phycobilisome; 1.
DR PIRSF; PIRSF000081; Phycocyanin; 1.
DR SUPFAM; SSF46458; SSF46458; 1.
DR TIGRFAMs; TIGR01338; phycocy_alpha; 1.
PE 3: Inferred from homology;
KW Antenna complex; Bile pigment; Chromophore; Electron transport; Membrane;
KW Photosynthesis; Phycobilisome; Thylakoid; Transport.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000250"
FT CHAIN 2..163
FT /note="C-phycocyanin alpha subunit"
FT /id="PRO_0000199138"
FT BINDING 85
FT /ligand="(2R,3E)-phycocyanobilin"
FT /ligand_id="ChEBI:CHEBI:85275"
FT /note="covalent, via 1 link"
FT /evidence="ECO:0000250|UniProtKB:P13530"
SQ SEQUENCE 163 AA; 17452 MW; C06D21BD5AE0A3E9 CRC64;
MSKTPLTEAV SAADSQGRFL SSTELQVAFG RFRQATSGLQ AAKSLTDNAQ RLIDGAANAF
YSKFPYTTTT PGANFASTAQ GKAKCSRDIG YYLRMVTYCL VAGGTGPIDE YLIAGIDEIN
RSFDLSPSWY VEALKYIKAN HGLSGDAASE ANSYIDYAIN ALS