ID   PHF11_BOVIN             Reviewed;         337 AA.
AC   Q2HJ93;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=PHD finger protein 11;
GN   Name=PHF11;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Uterus;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Positive regulator of Th1-type cytokine gene expression.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with BRCA1 and RELA. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
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DR   EMBL; BC113245; AAI13246.1; -; mRNA.
DR   RefSeq; NP_001039609.1; NM_001046144.1.
DR   AlphaFoldDB; Q2HJ93; -.
DR   SMR; Q2HJ93; -.
DR   STRING; 9913.ENSBTAP00000017493; -.
DR   PaxDb; Q2HJ93; -.
DR   Ensembl; ENSBTAT00000017493; ENSBTAP00000017493; ENSBTAG00000013159.
DR   GeneID; 513331; -.
DR   KEGG; bta:513331; -.
DR   CTD; 51131; -.
DR   VEuPathDB; HostDB:ENSBTAG00000013159; -.
DR   VGNC; VGNC:106864; PHF11.
DR   eggNOG; KOG1084; Eukaryota.
DR   GeneTree; ENSGT00950000182865; -.
DR   HOGENOM; CLU_076108_0_0_1; -.
DR   InParanoid; Q2HJ93; -.
DR   OMA; IYKLFCQ; -.
DR   OrthoDB; 783078at2759; -.
DR   TreeFam; TF325426; -.
DR   Proteomes; UP000009136; Chromosome 12.
DR   Bgee; ENSBTAG00000013159; Expressed in mesenteric lymph node and 107 other tissues.
DR   ExpressionAtlas; Q2HJ93; baseline and differential.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.40.10; -; 1.
DR   InterPro; IPR034732; EPHD.
DR   InterPro; IPR001965; Znf_PHD.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   SMART; SM00249; PHD; 1.
DR   PROSITE; PS51805; EPHD; 1.
PE   2: Evidence at transcript level;
KW   Activator; Metal-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..337
FT                   /note="PHD finger protein 11"
FT                   /id="PRO_0000385014"
FT   ZN_FING         42..78
FT                   /note="C2HC pre-PHD-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01146"
FT   ZN_FING         108..160
FT                   /note="PHD-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01146"
SQ   SEQUENCE   337 AA;  37951 MW;  54B9B4CED498F68D CRC64;
     MDTAGPSAPE STRGASWSEA QAARDIVPLP TGVFQVAERL QKRICALCPK DLECSVLYFA
     QSENIAAHEN CLLYSSALVE CEDYDPSNND RNFDVESVKK EIKRGRKLKC TFCGKKGATV
     GCDLKSCFKN YHFFCAKNDH AVLQADGRTG IYKVFCQQHA DPQNDLPSVK PLSGVFHSHY
     SEQTKPRHAC FSGVKRKRGR SKRHHVQPPE RMALKKEKDG RHTDAIVKAA FLKKCKEAGL
     LDALFEEILD KLHLIQERLM DETTAESDYE EIGTSLFDCR LFEDTLVNFQ AAIENQIHQS
     EERRRQLKEE IELLQDLKQT LCSGLQSSST SDSSLSS