ID   PHF11_RAT               Reviewed;         336 AA.
AC   Q5I0E2;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 1.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=PHD finger protein 11;
GN   Name=Phf11;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Lung;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: Positive regulator of Th1-type cytokine gene expression.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with BRCA1 and RELA. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC088433; AAH88433.1; -; mRNA.
DR   RefSeq; NP_001019443.1; NM_001024272.1.
DR   AlphaFoldDB; Q5I0E2; -.
DR   SMR; Q5I0E2; -.
DR   iPTMnet; Q5I0E2; -.
DR   PhosphoSitePlus; Q5I0E2; -.
DR   PRIDE; Q5I0E2; -.
DR   Ensembl; ENSRNOT00000114019; ENSRNOP00000086591; ENSRNOG00000053891.
DR   GeneID; 361051; -.
DR   KEGG; rno:361051; -.
DR   UCSC; RGD:1310853; rat.
DR   CTD; 51131; -.
DR   RGD; 1310853; Phf11.
DR   eggNOG; KOG1084; Eukaryota.
DR   GeneTree; ENSGT00950000182865; -.
DR   InParanoid; Q5I0E2; -.
DR   OrthoDB; 783078at2759; -.
DR   PhylomeDB; Q5I0E2; -.
DR   PRO; PR:Q5I0E2; -.
DR   Proteomes; UP000002494; Chromosome 15.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.40.10; -; 1.
DR   InterPro; IPR034732; EPHD.
DR   InterPro; IPR011011; Znf_FYVE_PHD.
DR   InterPro; IPR001965; Znf_PHD.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   SMART; SM00249; PHD; 1.
DR   SUPFAM; SSF57903; SSF57903; 1.
DR   PROSITE; PS51805; EPHD; 1.
PE   2: Evidence at transcript level;
KW   Activator; Metal-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..336
FT                   /note="PHD finger protein 11"
FT                   /id="PRO_0000385016"
FT   ZN_FING         25..61
FT                   /note="C2HC pre-PHD-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01146"
FT   ZN_FING         91..143
FT                   /note="PHD-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01146"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          139..179
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          303..336
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        145..161
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   336 AA;  37214 MW;  208485B5FB1FA0D9 CRC64;
     MAEETAPPCG PVSTGGSLSP EKMEKRTCAL CPDGHEWSVI YFAPSANIAA HENCLLYSSG
     LVECGPHDPR NPARSFAVKS VKKEIWRGRR LKCSLCNKGG ATVGCDLSSC RKSYHYVCAK
     KDHAIPQVDE DLGTYKIFCP EHPPQQEETT ERADSPSVKK TGKKKSLSSG PPTEPKKMKF
     SRFKRLMKEE PHGHKDAAVK APFLKKCLEA GLLTELFEQI LEKMDSIHGR FMDETASESD
     YEGIKTLLFD CGLFGDILRK FQEVIKSKTC EYEERLNQMK QKLEALADLQ ENLCSFQECG
     DLDPSGSTSG SLLPPEDHQC RCQESPEVQA GSGDSL