ID   PHF7_RAT                Reviewed;         380 AA.
AC   Q6AXW4;
DT   26-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2004, sequence version 1.
DT   03-AUG-2022, entry version 115.
DE   RecName: Full=PHD finger protein 7;
GN   Name=Phf7;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: May play a role in spermatogenesis. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
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DR   EMBL; BC079288; AAH79288.1; -; mRNA.
DR   RefSeq; NP_001012211.1; NM_001012211.1.
DR   AlphaFoldDB; Q6AXW4; -.
DR   SMR; Q6AXW4; -.
DR   STRING; 10116.ENSRNOP00000040832; -.
DR   PaxDb; Q6AXW4; -.
DR   GeneID; 364510; -.
DR   KEGG; rno:364510; -.
DR   UCSC; RGD:1308638; rat.
DR   CTD; 51533; -.
DR   RGD; 1308638; Phf7.
DR   VEuPathDB; HostDB:ENSRNOG00000018996; -.
DR   eggNOG; KOG1084; Eukaryota.
DR   HOGENOM; CLU_055746_0_1_1; -.
DR   InParanoid; Q6AXW4; -.
DR   OMA; CSQTVYH; -.
DR   OrthoDB; 199998at2759; -.
DR   PhylomeDB; Q6AXW4; -.
DR   TreeFam; TF325426; -.
DR   PRO; PR:Q6AXW4; -.
DR   Proteomes; UP000002494; Chromosome 16.
DR   Bgee; ENSRNOG00000018996; Expressed in testis and 19 other tissues.
DR   Genevisible; Q6AXW4; RN.
DR   GO; GO:0070013; C:intracellular organelle lumen; IEA:UniProt.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd15669; ePHD_PHF7_G2E3_like; 1.
DR   CDD; cd15496; PHD_PHF7_G2E3_like; 1.
DR   Gene3D; 3.30.40.10; -; 2.
DR   InterPro; IPR034732; EPHD.
DR   InterPro; IPR042013; PHF7/G2E3_ePHD.
DR   InterPro; IPR042012; PHF7/G2E3_PHD.
DR   InterPro; IPR011011; Znf_FYVE_PHD.
DR   InterPro; IPR001965; Znf_PHD.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   SMART; SM00249; PHD; 2.
DR   SUPFAM; SSF57903; SSF57903; 1.
DR   PROSITE; PS51805; EPHD; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   2: Evidence at transcript level;
KW   Metal-binding; Nucleus; Reference proteome; Zinc; Zinc-finger.
FT   CHAIN           1..380
FT                   /note="PHD finger protein 7"
FT                   /id="PRO_0000055998"
FT   ZN_FING         30..68
FT                   /note="C2HC pre-PHD-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01146"
FT   ZN_FING         96..145
FT                   /note="PHD-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01146"
FT   ZN_FING         159..207
FT                   /note="RING-type; degenerate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00175"
FT   REGION          1..23
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          352..380
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        7..23
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        352..368
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   380 AA;  43388 MW;  89A41C01AD5742F6 CRC64;
     MRTIKEKKEH PRLRKTARTK KVTHRKLSSG PVCLLCFQEP GDPEKLGEFL QKDNLCVHYF
     CLILSSKLPQ KGQPNRGLHG FMPEDIKKEA ARASRKVCFV CKRKGAAIRC QKDQCVQNFH
     LPCGQERGCL SQFFGEYKSY CGKHRPTQNI HQRSFGESCV LCCEDLSRAS VENIRSPCCS
     QAIYHRKCIQ KYAHTSAKHF FKCPQCNNRE EFPQEMLRMG IHIPDRDAAW ELEPGAFSEL
     YQRYQHCDAP ICLYEQGRDS FEDEGRWRLI LCATCGSHGT HRDCSSLRPN SKKWECNECL
     PASTEDSVSE NLGDTPCCSS TFCPHEPFLR ATSLEENPGS SWTNWLQPSL LEKPESSSGS
     SCQSWRSKGI KVTKDCKKSK