PHIPL_BOVIN
ID PHIPL_BOVIN Reviewed; 376 AA.
AC Q32L96;
DT 10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT 10-JUN-2008, sequence version 2.
DT 03-AUG-2022, entry version 95.
DE RecName: Full=Phytanoyl-CoA hydroxylase interacting protein-like;
GN Name=PHYHIPL;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford;
RX PubMed=19390049; DOI=10.1126/science.1169588;
RG The bovine genome sequencing and analysis consortium;
RT "The genome sequence of taurine cattle: a window to ruminant biology and
RT evolution.";
RL Science 324:522-528(2009).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=Crossbred X Angus; TISSUE=Liver;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May play a role in the development of the central system.
CC {ECO:0000250}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q32L96-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q32L96-2; Sequence=VSP_034071, VSP_034072;
CC -!- SIMILARITY: Belongs to the PHYHIP family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AAFC03071975; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC109692; AAI09693.1; -; mRNA.
DR RefSeq; NP_001073266.1; NM_001079798.1. [Q32L96-2]
DR RefSeq; XP_010818797.1; XM_010820495.1. [Q32L96-1]
DR AlphaFoldDB; Q32L96; -.
DR SMR; Q32L96; -.
DR STRING; 9913.ENSBTAP00000031317; -.
DR PaxDb; Q32L96; -.
DR PRIDE; Q32L96; -.
DR Ensembl; ENSBTAT00000031362; ENSBTAP00000031317; ENSBTAG00000010947. [Q32L96-2]
DR GeneID; 780878; -.
DR KEGG; bta:780878; -.
DR CTD; 84457; -.
DR VEuPathDB; HostDB:ENSBTAG00000010947; -.
DR eggNOG; ENOG502QQIT; Eukaryota.
DR GeneTree; ENSGT00390000014563; -.
DR HOGENOM; CLU_054218_2_1_1; -.
DR InParanoid; Q32L96; -.
DR OMA; EHHGNVM; -.
DR OrthoDB; 659430at2759; -.
DR TreeFam; TF314485; -.
DR Proteomes; UP000009136; Chromosome 28.
DR Bgee; ENSBTAG00000010947; Expressed in spermatid and 67 other tissues.
DR ExpressionAtlas; Q32L96; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR CDD; cd00063; FN3; 1.
DR Gene3D; 2.60.40.10; -; 1.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR042868; PHYHIP/PHYHIPL.
DR InterPro; IPR045545; PHYIP/PHIPL_C.
DR PANTHER; PTHR15698; PTHR15698; 1.
DR Pfam; PF00041; fn3; 1.
DR Pfam; PF19281; PHYHIP_C; 1.
DR SMART; SM00060; FN3; 1.
DR SUPFAM; SSF49265; SSF49265; 1.
DR PROSITE; PS50853; FN3; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Glycoprotein; Phosphoprotein; Reference proteome.
FT CHAIN 1..376
FT /note="Phytanoyl-CoA hydroxylase interacting protein-like"
FT /id="PRO_0000338643"
FT DOMAIN 52..161
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00316"
FT MOD_RES 12
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q8BGT8"
FT MOD_RES 15
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q8BGT8"
FT MOD_RES 25
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q8BGT8"
FT CARBOHYD 23
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 37
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT VAR_SEQ 252..288
FT /note="FEIAAEKLFNPNTNLYFGDFYCMYTAYHYVILVIAPV -> SPDPLLSIFVT
FT QMFSTEACTCHCHQERATTSQISELL (in isoform 2)"
FT /evidence="ECO:0000303|Ref.2"
FT /id="VSP_034071"
FT VAR_SEQ 289..376
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|Ref.2"
FT /id="VSP_034072"
SQ SEQUENCE 376 AA; 42562 MW; 5DC97CB772D672B0 CRC64;
MEVPRLDHAL NSPTSPCEEV IKNLSLEAIQ LCDRDGNKSQ DSGIAEMEEL PVPRNIKISN
ITCDSFKISW EMDSKSKDRI THYFIDLNKK ENKNSNKFKH KDVPTKLVAK AVPLPMTVRG
HWFLSPRTEY TVAVQTASKQ VDGDYVVSEW SEIIEFCTAD YSKVHLTQLL EKAEVIAGRM
LKFSVFYRNQ HKEYFDYIRE HHGNAMQPSV KDNSGSHGSP ISGKLEGIFF SCSTEFNTGK
PPQDSPYGRY RFEIAAEKLF NPNTNLYFGD FYCMYTAYHY VILVIAPVGS PGDEFCKQRL
PQLNSQDNKF LTCREEDGML VYHHAQDVIL EVIYTDPVGL SLGTVAEITG HQLMSLSTAN
AKKDPSCKTC NISVGR