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PHIPL_BOVIN
ID   PHIPL_BOVIN             Reviewed;         376 AA.
AC   Q32L96;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   10-JUN-2008, sequence version 2.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Phytanoyl-CoA hydroxylase interacting protein-like;
GN   Name=PHYHIPL;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hereford;
RX   PubMed=19390049; DOI=10.1126/science.1169588;
RG   The bovine genome sequencing and analysis consortium;
RT   "The genome sequence of taurine cattle: a window to ruminant biology and
RT   evolution.";
RL   Science 324:522-528(2009).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play a role in the development of the central system.
CC       {ECO:0000250}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=1;
CC         IsoId=Q32L96-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q32L96-2; Sequence=VSP_034071, VSP_034072;
CC   -!- SIMILARITY: Belongs to the PHYHIP family. {ECO:0000305}.
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DR   EMBL; AAFC03071975; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC109692; AAI09693.1; -; mRNA.
DR   RefSeq; NP_001073266.1; NM_001079798.1. [Q32L96-2]
DR   RefSeq; XP_010818797.1; XM_010820495.1. [Q32L96-1]
DR   AlphaFoldDB; Q32L96; -.
DR   SMR; Q32L96; -.
DR   STRING; 9913.ENSBTAP00000031317; -.
DR   PaxDb; Q32L96; -.
DR   PRIDE; Q32L96; -.
DR   Ensembl; ENSBTAT00000031362; ENSBTAP00000031317; ENSBTAG00000010947. [Q32L96-2]
DR   GeneID; 780878; -.
DR   KEGG; bta:780878; -.
DR   CTD; 84457; -.
DR   VEuPathDB; HostDB:ENSBTAG00000010947; -.
DR   eggNOG; ENOG502QQIT; Eukaryota.
DR   GeneTree; ENSGT00390000014563; -.
DR   HOGENOM; CLU_054218_2_1_1; -.
DR   InParanoid; Q32L96; -.
DR   OMA; EHHGNVM; -.
DR   OrthoDB; 659430at2759; -.
DR   TreeFam; TF314485; -.
DR   Proteomes; UP000009136; Chromosome 28.
DR   Bgee; ENSBTAG00000010947; Expressed in spermatid and 67 other tissues.
DR   ExpressionAtlas; Q32L96; baseline and differential.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   CDD; cd00063; FN3; 1.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR003961; FN3_dom.
DR   InterPro; IPR036116; FN3_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR042868; PHYHIP/PHYHIPL.
DR   InterPro; IPR045545; PHYIP/PHIPL_C.
DR   PANTHER; PTHR15698; PTHR15698; 1.
DR   Pfam; PF00041; fn3; 1.
DR   Pfam; PF19281; PHYHIP_C; 1.
DR   SMART; SM00060; FN3; 1.
DR   SUPFAM; SSF49265; SSF49265; 1.
DR   PROSITE; PS50853; FN3; 1.
PE   2: Evidence at transcript level;
KW   Alternative splicing; Glycoprotein; Phosphoprotein; Reference proteome.
FT   CHAIN           1..376
FT                   /note="Phytanoyl-CoA hydroxylase interacting protein-like"
FT                   /id="PRO_0000338643"
FT   DOMAIN          52..161
FT                   /note="Fibronectin type-III"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00316"
FT   MOD_RES         12
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q8BGT8"
FT   MOD_RES         15
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q8BGT8"
FT   MOD_RES         25
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q8BGT8"
FT   CARBOHYD        23
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        37
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   VAR_SEQ         252..288
FT                   /note="FEIAAEKLFNPNTNLYFGDFYCMYTAYHYVILVIAPV -> SPDPLLSIFVT
FT                   QMFSTEACTCHCHQERATTSQISELL (in isoform 2)"
FT                   /evidence="ECO:0000303|Ref.2"
FT                   /id="VSP_034071"
FT   VAR_SEQ         289..376
FT                   /note="Missing (in isoform 2)"
FT                   /evidence="ECO:0000303|Ref.2"
FT                   /id="VSP_034072"
SQ   SEQUENCE   376 AA;  42562 MW;  5DC97CB772D672B0 CRC64;
     MEVPRLDHAL NSPTSPCEEV IKNLSLEAIQ LCDRDGNKSQ DSGIAEMEEL PVPRNIKISN
     ITCDSFKISW EMDSKSKDRI THYFIDLNKK ENKNSNKFKH KDVPTKLVAK AVPLPMTVRG
     HWFLSPRTEY TVAVQTASKQ VDGDYVVSEW SEIIEFCTAD YSKVHLTQLL EKAEVIAGRM
     LKFSVFYRNQ HKEYFDYIRE HHGNAMQPSV KDNSGSHGSP ISGKLEGIFF SCSTEFNTGK
     PPQDSPYGRY RFEIAAEKLF NPNTNLYFGD FYCMYTAYHY VILVIAPVGS PGDEFCKQRL
     PQLNSQDNKF LTCREEDGML VYHHAQDVIL EVIYTDPVGL SLGTVAEITG HQLMSLSTAN
     AKKDPSCKTC NISVGR
 
 
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