PHIPL_DANRE
ID PHIPL_DANRE Reviewed; 377 AA.
AC A4QNW7; Q641M5;
DT 10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT 15-MAY-2007, sequence version 1.
DT 03-AUG-2022, entry version 84.
DE RecName: Full=Phytanoyl-CoA hydroxylase-interacting protein-like;
GN Name=phyhipl; ORFNames=zgc:100983;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC TISSUE=Embryo, and Testis;
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May play a role in the development of the central system.
CC {ECO:0000250}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=A4QNW7-1; Sequence=Displayed;
CC Name=2;
CC IsoId=A4QNW7-2; Sequence=VSP_034073;
CC -!- SIMILARITY: Belongs to the PHYHIP family. {ECO:0000305}.
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DR EMBL; BC082295; AAH82295.1; -; mRNA.
DR EMBL; BC139549; AAI39550.1; -; mRNA.
DR RefSeq; NP_001005602.2; NM_001005602.2. [A4QNW7-1]
DR RefSeq; XP_005158063.1; XM_005158006.3. [A4QNW7-2]
DR RefSeq; XP_017213902.1; XM_017358413.1. [A4QNW7-2]
DR AlphaFoldDB; A4QNW7; -.
DR SMR; A4QNW7; -.
DR STRING; 7955.ENSDARP00000094312; -.
DR PaxDb; A4QNW7; -.
DR Ensembl; ENSDART00000103536; ENSDARP00000094312; ENSDARG00000070498. [A4QNW7-1]
DR Ensembl; ENSDART00000134608; ENSDARP00000114750; ENSDARG00000070498. [A4QNW7-2]
DR GeneID; 100004913; -.
DR KEGG; dre:100004913; -.
DR CTD; 100004913; -.
DR ZFIN; ZDB-GENE-040927-27; phyhiplb.
DR eggNOG; ENOG502QQIT; Eukaryota.
DR GeneTree; ENSGT00390000014563; -.
DR HOGENOM; CLU_054218_1_0_1; -.
DR InParanoid; A4QNW7; -.
DR PhylomeDB; A4QNW7; -.
DR TreeFam; TF314485; -.
DR PRO; PR:A4QNW7; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Chromosome 12.
DR Bgee; ENSDARG00000070498; Expressed in retina and 26 other tissues.
DR ExpressionAtlas; A4QNW7; baseline.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR CDD; cd00063; FN3; 1.
DR Gene3D; 2.60.40.10; -; 1.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR042868; PHYHIP/PHYHIPL.
DR InterPro; IPR045545; PHYIP/PHIPL_C.
DR PANTHER; PTHR15698; PTHR15698; 1.
DR Pfam; PF00041; fn3; 1.
DR Pfam; PF19281; PHYHIP_C; 1.
DR SMART; SM00060; FN3; 1.
DR SUPFAM; SSF49265; SSF49265; 1.
DR PROSITE; PS50853; FN3; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Reference proteome.
FT CHAIN 1..377
FT /note="Phytanoyl-CoA hydroxylase-interacting protein-like"
FT /id="PRO_0000338644"
FT DOMAIN 52..161
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00316"
FT VAR_SEQ 1..46
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|Ref.1"
FT /id="VSP_034073"
FT CONFLICT 192
FT /note="K -> R (in Ref. 1; AAH82295)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 377 AA; 42504 MW; 18721C206366C107 CRC64;
MEVPRVGHSI SSPTSPCEDM MKNLSLDAIQ LCEREGNKSL DSGIAEMEEL PVPQNIKISN
ITCDSFKICW DMDSRSKERI THYFIDLNKK ENKNANKFKH KDVPTKLVAK AVPLPMTVRG
HWFLSPRTEY TVAVQTASKQ GDGDYAVSEW SEINEFCTAD YSTVHLTQLM EKAEVIAGRM
LRFSVFYRNQ HKEYFDHARE AQNNKMLPSV KDNSGSHGSP ISGKLEGIFF SCNTEFNTGK
PPQDSPYGRY RYQLPAEALF SPKTNLYFGD FYCMYTAYHY VILVIAPQGS PGDDFCKQRL
PALDIANNRF MTCSEDEDGQ LVFHHAQDLI LEVIYTDPVD LSLGTVAEIS GHQLMSLSTV
NAKKDPSCKT CNISVGR