ID   PHK1_LACPL              Reviewed;         788 AA.
AC   Q88U67; F9URE9;
DT   31-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=Probable phosphoketolase 1 {ECO:0000255|HAMAP-Rule:MF_01403};
DE            EC=4.1.2.- {ECO:0000255|HAMAP-Rule:MF_01403};
GN   OrderedLocusNames=lp_2659;
OS   Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)
OS   (Lactobacillus plantarum).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Lactiplantibacillus.
OX   NCBI_TaxID=220668;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-793 / NCIMB 8826 / WCFS1;
RX   PubMed=12566566; DOI=10.1073/pnas.0337704100;
RA   Kleerebezem M., Boekhorst J., van Kranenburg R., Molenaar D., Kuipers O.P.,
RA   Leer R., Tarchini R., Peters S.A., Sandbrink H.M., Fiers M.W.E.J.,
RA   Stiekema W., Klein Lankhorst R.M., Bron P.A., Hoffer S.M.,
RA   Nierop Groot M.N., Kerkhoven R., De Vries M., Ursing B., De Vos W.M.,
RA   Siezen R.J.;
RT   "Complete genome sequence of Lactobacillus plantarum WCFS1.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:1990-1995(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-793 / NCIMB 8826 / WCFS1;
RX   PubMed=22156394; DOI=10.1128/jb.06275-11;
RA   Siezen R.J., Francke C., Renckens B., Boekhorst J., Wels M.,
RA   Kleerebezem M., van Hijum S.A.;
RT   "Complete resequencing and reannotation of the Lactobacillus plantarum
RT   WCFS1 genome.";
RL   J. Bacteriol. 194:195-196(2012).
CC   -!- COFACTOR:
CC       Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01403};
CC   -!- SIMILARITY: Belongs to the XFP family. {ECO:0000255|HAMAP-
CC       Rule:MF_01403}.
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DR   EMBL; AL935263; CCC79788.1; -; Genomic_DNA.
DR   RefSeq; WP_011101870.1; NC_004567.2.
DR   RefSeq; YP_004890302.1; NC_004567.2.
DR   AlphaFoldDB; Q88U67; -.
DR   SMR; Q88U67; -.
DR   STRING; 220668.lp_2659; -.
DR   PRIDE; Q88U67; -.
DR   EnsemblBacteria; CCC79788; CCC79788; lp_2659.
DR   GeneID; 57026049; -.
DR   KEGG; lpl:lp_2659; -.
DR   PATRIC; fig|220668.9.peg.2227; -.
DR   eggNOG; COG3957; Bacteria.
DR   HOGENOM; CLU_013954_2_0_9; -.
DR   OMA; LSTMDHC; -.
DR   PhylomeDB; Q88U67; -.
DR   BioCyc; LPLA220668:G1GW0-2279-MON; -.
DR   BRENDA; 4.1.2.9; 2849.
DR   Proteomes; UP000000432; Chromosome.
DR   GO; GO:0016832; F:aldehyde-lyase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.920; -; 1.
DR   HAMAP; MF_01403; Phosphoketolase; 1.
DR   InterPro; IPR023962; Phosphoketolase.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   InterPro; IPR005593; Xul5P/Fru6P_PKetolase.
DR   InterPro; IPR018969; Xul5P/Fru6P_PKetolase_C.
DR   InterPro; IPR019790; Xul5P/Fru6P_PKetolase_CS.
DR   InterPro; IPR018970; Xul5P/Fru6P_PKetolase_N.
DR   InterPro; IPR019789; Xul5P/Fru6P_PKetolase_ThDP_BS.
DR   PANTHER; PTHR31273; PTHR31273; 1.
DR   Pfam; PF03894; XFP; 1.
DR   Pfam; PF09363; XFP_C; 1.
DR   Pfam; PF09364; XFP_N; 1.
DR   PIRSF; PIRSF017245; Phosphoketolase; 1.
DR   SUPFAM; SSF52518; SSF52518; 2.
DR   PROSITE; PS60002; PHOSPHOKETOLASE_1; 1.
DR   PROSITE; PS60003; PHOSPHOKETOLASE_2; 1.
PE   3: Inferred from homology;
KW   Lyase; Reference proteome; Thiamine pyrophosphate.
FT   CHAIN           1..788
FT                   /note="Probable phosphoketolase 1"
FT                   /id="PRO_0000193878"
SQ   SEQUENCE   788 AA;  88731 MW;  215485F754AA48E9 CRC64;
     MTTDYSSPAY LQKVDKYWRA ANYLSVGQLY LKDNPLLQRP LKASDVKVHP IGHWGTIAGQ
     NFIYAHLNRV INKYGLKMFY VEGPGHGGQV MVSNSYLDGT YTDIYPEITQ DVEGMQKLFK
     QFSFPGGVAS HAAPETPGSI HEGGELGYSI SHGVGAILDN PDEIAAVVVG DGESETGPLA
     TSWQSTKFIN PINDGAVLPI LNLNGFKISN PTIFGRTSDA KIKEYFESMN WEPIFVEGDD
     PEKVHPALAK AMDEAVEKIK AIQKHARENN DATLPVWPMI VFRAPKGWTG PKSWDGDKIE
     GSFRAHQIPI PVDQNDMEHA DALVDWLESY QPKELFNEDG SLKDDIKEII PTGDSRMAAN
     PITNGGVDPK ALNLPNFRDY AVDTSKEGAN VKQDMIVWSD YLRDVIKKNP DNFRLFGPDE
     TMSNRLYGVF ETTNRQWMED IHPDSDQYEA PAGRVLDAQL SEHQAEGWLE GYVLTGRHGL
     FASYEAFLRV VDSMLTQHFK WLRKANELDW RKKYPSLNII AASTVFQQDH NGYTHQDPGA
     LTHLAEKKPE YIREYLPADA NTLLAVGDVI FRSQEKINYV VTSKHPRQQW FSIEEAKQLV
     DNGLGIIDWA STDQGSEPDI VFAAAGTEPT LETLAAIQLL HDSFPEMKIR FVNVVDILKL
     RSPEKDPRGL SDAEFDHYFT KDKPVVFAFH GYEDLVRDIF FDRHNHNLYV HGYRENGDIT
     TPFDVRVMNQ MDRFDLAKSA IAAQPAMENT GAAFVQSMDN MLAKHNAYIR DAGTDLPEVN
     DWQWKGLK