ID   PHK1_RHIME              Reviewed;         789 AA.
AC   Q92T74;
DT   06-JUN-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=Probable phosphoketolase 1;
DE            EC=4.1.2.-;
GN   OrderedLocusNames=R00106; ORFNames=SMc04146;
OS   Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS   meliloti).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=266834;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=11481430; DOI=10.1073/pnas.161294398;
RA   Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J.,
RA   Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S.,
RA   Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D., Pohl T.,
RA   Portetelle D., Puehler A., Purnelle B., Ramsperger U., Renard C.,
RA   Thebault P., Vandenbol M., Weidner S., Galibert F.;
RT   "Analysis of the chromosome sequence of the legume symbiont Sinorhizobium
RT   meliloti strain 1021.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=11474104; DOI=10.1126/science.1060966;
RA   Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA   Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA   Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA   Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA   Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA   Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA   Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA   Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA   Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA   Wong K., Yeh K.-C., Batut J.;
RT   "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL   Science 293:668-672(2001).
CC   -!- COFACTOR:
CC       Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC         Evidence={ECO:0000305};
CC   -!- SIMILARITY: Belongs to the XFP family. {ECO:0000305}.
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DR   EMBL; AL591688; CAC41493.1; -; Genomic_DNA.
DR   RefSeq; NP_384212.2; NC_003047.1.
DR   AlphaFoldDB; Q92T74; -.
DR   SMR; Q92T74; -.
DR   STRING; 266834.SMc04146; -.
DR   PRIDE; Q92T74; -.
DR   EnsemblBacteria; CAC41493; CAC41493; SMc04146.
DR   KEGG; sme:SMc04146; -.
DR   PATRIC; fig|266834.11.peg.1464; -.
DR   eggNOG; COG3957; Bacteria.
DR   Proteomes; UP000001976; Chromosome.
DR   GO; GO:0016832; F:aldehyde-lyase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.920; -; 1.
DR   HAMAP; MF_01403; Phosphoketolase; 1.
DR   InterPro; IPR023962; Phosphoketolase.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   InterPro; IPR005593; Xul5P/Fru6P_PKetolase.
DR   InterPro; IPR018969; Xul5P/Fru6P_PKetolase_C.
DR   InterPro; IPR019790; Xul5P/Fru6P_PKetolase_CS.
DR   InterPro; IPR018970; Xul5P/Fru6P_PKetolase_N.
DR   InterPro; IPR019789; Xul5P/Fru6P_PKetolase_ThDP_BS.
DR   PANTHER; PTHR31273; PTHR31273; 1.
DR   Pfam; PF03894; XFP; 1.
DR   Pfam; PF09363; XFP_C; 1.
DR   Pfam; PF09364; XFP_N; 1.
DR   PIRSF; PIRSF017245; Phosphoketolase; 1.
DR   SUPFAM; SSF52518; SSF52518; 2.
DR   PROSITE; PS60002; PHOSPHOKETOLASE_1; 1.
DR   PROSITE; PS60003; PHOSPHOKETOLASE_2; 1.
PE   3: Inferred from homology;
KW   Lyase; Reference proteome; Thiamine pyrophosphate.
FT   CHAIN           1..789
FT                   /note="Probable phosphoketolase 1"
FT                   /id="PRO_0000193886"
SQ   SEQUENCE   789 AA;  88974 MW;  32739E3A7825750C CRC64;
     MDAYWRASNY LSVGQIYLLD NPLLSEPLKR EHIKPRLLGH WGTSPGLNML YVHLNRVIKR
     DDLEMMYVIG PGHGGPSLVA HAYLEGTYSE VYPDISQDAE GLRKLFKQFS FPGGIPSHVA
     PETPGSIHEG GELGYALSHA YGAAFDNPEL IVACVVGDGE AETGPLATGW HGNKFLNPAR
     DGCVLPILHL NGYKIANPCF LARIPREELQ KFFEGMGYAP LFVEGHDPAD VHQQLAAALD
     TALADIRRIQ TDARVNGNLK RPAWPMIVFR TPKGWTCPAE IDGKKCEDYW RSHQVPMGDM
     DKPEHIRILE GWMKSYRPEE LFDGDGRLTA ELAALAPTGR RRMSDNPHAN GGLLLRDLKM
     PDFRDYAVAV QSPGAATAES ARVMGSYLRD VMKLNLKSGN FRLFSPDENN SNRWQDVLEV
     TDRCFMADIY PEDDHLSPDG RLMEVLSEHQ SQGWLEGYLL TGRHGFFSCY EAFIHIIDSM
     FNQHAKWLKV CNEIPWRRPI ASLNYFLSSH VWRQDHNGFS HQDPGFIDHV VNKKADIIRV
     YLPPDANTLL SVTDHCLRSR NYINVVVAGK QPSPQWLTMD QAVKHCTEGL GIWEWASNDK
     GCEPDVVMAC CGDVPTLETL AAVQLLREHL PELKVRVINV VNLMKLQPSG EHPHGLPDRD
     FDALFTKDKP IIFAFHGYPW LIHRLTYRRT NHANLHVRGY KEEGTTTTPF DMVVLNHLDR
     FHLVEDVIDR LPQLGARAAY FKQAIHERLI DHRHHIEKYG EDMPVISGWK WGAGSAGKAQ
     GTSTKGDNV