ID   PHK2_RHIME              Reviewed;         779 AA.
AC   Q92ZA4;
DT   06-JUN-2002, integrated into UniProtKB/Swiss-Prot.
DT   06-JUN-2002, sequence version 2.
DT   25-MAY-2022, entry version 92.
DE   RecName: Full=Probable phosphoketolase 2;
DE            EC=4.1.2.-;
GN   OrderedLocusNames=RA0587; ORFNames=SMa1084;
OS   Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS   meliloti).
OG   Plasmid pSymA (megaplasmid 1).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=266834;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=11481432; DOI=10.1073/pnas.161294798;
RA   Barnett M.J., Fisher R.F., Jones T., Komp C., Abola A.P., Barloy-Hubler F.,
RA   Bowser L., Capela D., Galibert F., Gouzy J., Gurjal M., Hong A., Huizar L.,
RA   Hyman R.W., Kahn D., Kahn M.L., Kalman S., Keating D.H., Palm C.,
RA   Peck M.C., Surzycki R., Wells D.H., Yeh K.-C., Davis R.W., Federspiel N.A.,
RA   Long S.R.;
RT   "Nucleotide sequence and predicted functions of the entire Sinorhizobium
RT   meliloti pSymA megaplasmid.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:9883-9888(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=11474104; DOI=10.1126/science.1060966;
RA   Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA   Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA   Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA   Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA   Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA   Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA   Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA   Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA   Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA   Wong K., Yeh K.-C., Batut J.;
RT   "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL   Science 293:668-672(2001).
CC   -!- COFACTOR:
CC       Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC         Evidence={ECO:0000305};
CC   -!- SIMILARITY: Belongs to the XFP family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAK65245.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE006469; AAK65245.1; ALT_INIT; Genomic_DNA.
DR   PIR; C95335; C95335.
DR   RefSeq; NP_435833.1; NC_003037.1.
DR   AlphaFoldDB; Q92ZA4; -.
DR   SMR; Q92ZA4; -.
DR   PRIDE; Q92ZA4; -.
DR   EnsemblBacteria; AAK65245; AAK65245; SMa1084.
DR   KEGG; sme:SMa1084; -.
DR   PATRIC; fig|266834.11.peg.602; -.
DR   HOGENOM; CLU_013954_2_0_5; -.
DR   Proteomes; UP000001976; Plasmid pSymA.
DR   GO; GO:0016832; F:aldehyde-lyase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.920; -; 1.
DR   HAMAP; MF_01403; Phosphoketolase; 1.
DR   InterPro; IPR023962; Phosphoketolase.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   InterPro; IPR005593; Xul5P/Fru6P_PKetolase.
DR   InterPro; IPR018969; Xul5P/Fru6P_PKetolase_C.
DR   InterPro; IPR019790; Xul5P/Fru6P_PKetolase_CS.
DR   InterPro; IPR018970; Xul5P/Fru6P_PKetolase_N.
DR   InterPro; IPR019789; Xul5P/Fru6P_PKetolase_ThDP_BS.
DR   PANTHER; PTHR31273; PTHR31273; 1.
DR   Pfam; PF03894; XFP; 1.
DR   Pfam; PF09363; XFP_C; 1.
DR   Pfam; PF09364; XFP_N; 1.
DR   PIRSF; PIRSF017245; Phosphoketolase; 1.
DR   SUPFAM; SSF52518; SSF52518; 2.
DR   SUPFAM; SSF52922; SSF52922; 1.
DR   PROSITE; PS60002; PHOSPHOKETOLASE_1; 1.
DR   PROSITE; PS60003; PHOSPHOKETOLASE_2; 1.
PE   3: Inferred from homology;
KW   Lyase; Plasmid; Reference proteome; Thiamine pyrophosphate.
FT   CHAIN           1..779
FT                   /note="Probable phosphoketolase 2"
FT                   /id="PRO_0000193887"
SQ   SEQUENCE   779 AA;  87068 MW;  1F857C17673A11D6 CRC64;
     MDAYWRAANY LSVGQIYLRD NPLLKQKLTL ADVKPRLLGH WGTTPGLNFL YVHLNRLIQT
     HDLNMIYVTG PGHGGPGLVA NTYLEGTYSE LYPEVSQDEA GIKRLFTQFS YPGGIPSHVA
     AEVPGSINEG GELGYCLMHA YGAVFDNPDL IAACVVGDGE AETGALATSW HSNKFLNPAR
     DGAVLPILHL NGYKIANPTV LARISHDELE ALFMGYGYEP LFVEGADPRQ MHQLMASALD
     KAHGKIAEIQ RQARSRGFSD RPAWPMIIFR SPKGWTGPRE VDGKKTEGTW RSHQVPLAKL
     AEVPAHLGIL EEWLKSYRPW ELFDESGSLR PELRELAPKG ERRMGANPHA NGGLLLKDLN
     LPDFRQYAVE IGIPGTVTAE STRTAGLYLR DVMKLNAQER NFRIFGPDET ESNRLSPVFQ
     ETDRVFTGDI LASDMQLSPD GRVMEVLSEQ LCQGWLEGYL LTGRHGFFSC YEAFIHIVDS
     MFNQHAKWLK VCREVPWRKP IASLTYLLTS HVWRQDHNGF SHQDPGFIDH VANKKADIIR
     VYLPPDANTL LSVVDHCARS RDYINVIVAG KQPQLQWLDM GAAVAHCRAG LGVWEWASND
     EGDPDAVVAC AGDVPTMEAL AAVMIVREAF PSLRLRVVNV VDLMALQAPS QHPHGIADDA
     FDRMFTTDKP VIFAYHGYPG LIHRLTYRRT NHANFHVHGY QEEGTTTTPF DMAVLNKLDR
     FHLAKAVVER VPSLASPREG FAHFVESKLA EHDAYIRENG EDLPEIRNWR WLASAVDAQ