ID   PHK_BIFA0               Reviewed;         825 AA.
AC   B8DUT6;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   03-MAR-2009, sequence version 1.
DT   03-AUG-2022, entry version 63.
DE   RecName: Full=Probable phosphoketolase {ECO:0000255|HAMAP-Rule:MF_01403};
DE            EC=4.1.2.- {ECO:0000255|HAMAP-Rule:MF_01403};
GN   OrderedLocusNames=BLA_1483;
OS   Bifidobacterium animalis subsp. lactis (strain AD011).
OC   Bacteria; Actinobacteria; Bifidobacteriales; Bifidobacteriaceae;
OC   Bifidobacterium.
OX   NCBI_TaxID=442563;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AD011;
RX   PubMed=19011029; DOI=10.1128/jb.01515-08;
RA   Kim J.F., Jeong H., Yu D.S., Choi S.-H., Hur C.-G., Park M.-S., Yoon S.H.,
RA   Kim D.-W., Ji G.E., Park H.-S., Oh T.K.;
RT   "Genome sequence of the probiotic bacterium Bifidobacterium animalis subsp.
RT   lactis AD011.";
RL   J. Bacteriol. 191:678-679(2009).
CC   -!- COFACTOR:
CC       Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01403};
CC   -!- SIMILARITY: Belongs to the XFP family. {ECO:0000255|HAMAP-
CC       Rule:MF_01403}.
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DR   EMBL; CP001213; ACL29765.1; -; Genomic_DNA.
DR   RefSeq; WP_004217768.1; NC_011835.1.
DR   AlphaFoldDB; B8DUT6; -.
DR   SMR; B8DUT6; -.
DR   STRING; 442563.BLA_1483; -.
DR   EnsemblBacteria; ACL29765; ACL29765; BLA_1483.
DR   GeneID; 66533313; -.
DR   KEGG; bla:BLA_1483; -.
DR   HOGENOM; CLU_013954_2_0_11; -.
DR   OMA; LSTMDHC; -.
DR   Proteomes; UP000002456; Chromosome.
DR   GO; GO:0016832; F:aldehyde-lyase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.920; -; 1.
DR   HAMAP; MF_01403; Phosphoketolase; 1.
DR   InterPro; IPR023962; Phosphoketolase.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   InterPro; IPR005593; Xul5P/Fru6P_PKetolase.
DR   InterPro; IPR018969; Xul5P/Fru6P_PKetolase_C.
DR   InterPro; IPR019790; Xul5P/Fru6P_PKetolase_CS.
DR   InterPro; IPR018970; Xul5P/Fru6P_PKetolase_N.
DR   InterPro; IPR019789; Xul5P/Fru6P_PKetolase_ThDP_BS.
DR   PANTHER; PTHR31273; PTHR31273; 1.
DR   Pfam; PF03894; XFP; 1.
DR   Pfam; PF09363; XFP_C; 1.
DR   Pfam; PF09364; XFP_N; 1.
DR   PIRSF; PIRSF017245; Phosphoketolase; 1.
DR   SUPFAM; SSF52518; SSF52518; 2.
DR   PROSITE; PS60002; PHOSPHOKETOLASE_1; 1.
DR   PROSITE; PS60003; PHOSPHOKETOLASE_2; 1.
PE   3: Inferred from homology;
KW   Lyase; Reference proteome; Thiamine pyrophosphate.
FT   CHAIN           1..825
FT                   /note="Probable phosphoketolase"
FT                   /id="PRO_1000184576"
SQ   SEQUENCE   825 AA;  92502 MW;  0E1D963806C61797 CRC64;
     MTNPVIGTPW QKLDRPVSEE AIEGMDKYWR VANYMSIGQI YLRSNPLMKE PFTRDDVKHR
     LVGHWGTTPG LNFLLAHINR LIADHQQNTV FIMGPGHGGP AGTAQSYIDG TYTEYYPNIT
     KDEAGLQKFF RQFSYPGGIP SHFAPETPGS IHEGGELGYA LSHAYGAIMD NPSLFVPCII
     GDGEAETGPL ATGWQSNKLV NPRTDGIVLP ILHLNGYKIA NPTILARISD EELHDFFRGM
     GYHPYEFVAG FDNEDHLSIH RRFAELFETI FDEICDIKAA AQTDDMTRPF YPMLIFRTPK
     GWTCPKFIDG KKTEGSWRAH QVPLASARDT EAHFEVLKGW MESYKPEELF NADGSIKEDV
     TAFMPKGELR IGANPNANGG RIREDLKLPE LDQYEITGVK EYGHGWGQVE APRSLGAYCR
     DIIKNNPDSF RVFGPDETAS NRLNATYEVT KKQWDNGYLS ALVDENMAVT GQVVEQLSEH
     QCEGFLEAYL LTGRHGIWSS YESFVHVIDS MLNQHAKWLE ATVREIPWRK PISSVNLLVS
     SHVWRQDHNG FSHQDPGVTS VLLNKTFNND HVTNIYFATD ANMLLAIAEK CFKSTNKINA
     IFAGKQPAAT WITLDEARAE LEAGAAEWKW ASNAKSNDEV QVVLAAAGDV PTQEIMAASD
     ALNKMGIKFK VVNVVDLIKL QSSKENDEAM SDEDFADLFT ADKPVLFAYH SYAQDVRGLI
     YDRPNHDNFT VVGYKEQGST TTPFDMVRVN DMDRYALQAK ALELIDADKY ADKINELNEF
     RKTAFQFAVD NGYDIPEFTD WVYPDVKVDE TSMLSATAAT AGDNE